- Expression of adhesion molecules on CD34+ cells from steady-state bone marrow before and after mobilization and their association with the yield of CD34+ cells
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Cecyn KZ, Kimura EY, Lima DM, Yamamoto M, Bordin JO, de Oliveira JSR
- KMID: 2414366
- Blood Res.
- 2018 Mar;53(1):61-70.
- doi: 10.5045/br.2018.53.1.61
BACKGROUND: Cell adhesion molecules (CAMs) expressed on hematopoietic progenitor cells (HPCs), endothelial cells, and stromal cells play a pivotal role in the mobilization of CD34+ cells. Herein, we conducted a... -
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- Simultaneous Inhibition of CXCR4 and VLA-4 Exhibits Combinatorial Effect in Overcoming Stroma-Mediated Chemotherapy Resistance in Mantle Cell Lymphoma Cells
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Kim YR, Eom KS
- KMID: 2150820
- Immune Netw.
- 2014 Dec;14(6):296-306.
- doi: 10.4110/in.2014.14.6.296
There is growing evidence that crosstalk between mantle cell lymphoma (MCL) cells and stromal microenvironments, such as bone marrow and secondary lymphoid tissues, promotes tumor progression by enhancing survival and... -
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- Multiple sclerosis
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Kim KK
- KMID: 1847872
- J Korean Med Assoc.
- 2013 Aug;56(8):702-708.
- doi: 10.5124/jkma.2013.56.8.702
Multiple sclerosis (MS) is the most common demyelinating disease affecting the central nervous system of young adults living in the western world. MS should be strongly suspected when a young... -
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- The role of the alpha4 integrin-paxillin interaction in regulating leukocyte trafficking
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Rose DM
- KMID: 1094143
- Exp Mol Med.
- 2006 Jun;38(3):191-195.
The movement of leukocytes from the blood into peripheral tissues is a central feature of immune surveillance, but also contributes to the pathogenesis of inflammatory and autoimmune diseases. Integrins are... -
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- Stem Cells Expressing Homing Receptors Could be Expanded From Cryopreserved and Unselected Cord Blood
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Lee YH, Han JY, Seo SY, Kim KH, Lee YA, Lee YS, Lee HS, Hur WJ, Han H, Kwon HC, Kim JS, Kim HJ
- KMID: 1733500
- J Korean Med Sci.
- 2004 Oct;19(5):635-639.
- doi: 10.3346/jkms.2004.19.5.635
We assessed the cytokine combinations that are best for ex vivo expansion of cord blood (CB) and the increment for cell numbers of nucleated cells, as well as stem cells... -
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- Regulation of Adhesion Molecule Expression and Stromal Cell-Derived Factor-1 Production in Human Bone Marrow Cells by Interferon-gamma, Tumor Necrosis Factor-alpha, and Transforming Growth Factor-beta1: Implications in Bone Marrow Homing of Hematopoietic Cells
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Jo DY, Hwang JH, Chung HK, Park SE, Park SJ, Kwak SK, Yun HJ, Seong CM, Kim S
- KMID: 2014031
- Korean J Hematol.
- 2003 May;38(2):91-99.
BACKGROUND: It is well known that harmonious interactions among adhesion molecules and stromal cell-derived factor-1 (SDF-1)-mediated chemoattraction signalling via CXCR4 are needed for bone marrow homing of hematopoietic stem cells... -
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- Effects of Short-Term Incubation of Hematopoietic Cells with Hematopoietic Growth Factors on CXCR4 Expression and Stromal Cell-Derived Factor-1-Mediated Transendothelial Migration
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Jo DY, Hwang JH, Kwak SK, Shin HY, Kim SE, Yun HJ, Seong CM, Kim SY
- KMID: 2143334
- Korean J Hematol.
- 2001 Nov;36(4):324-334.
BACKGROUND: There has been contradictory reports regarding the homing potential of hematopoietic cells briefly exposed to hematopoietic growth factors in vitro. To get a resolution to this controversy, we... -
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- The Effect of Dexamethasone and Transforming Growth Factor-beta1 on the Cytokine Induced Expression of VCAM-1 in Glomerular Endothelial Cells
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Park SK, Jung YO, Lee JS, Chang YH, Yang WS, Chang HS, Ahn H, Lee JD
- KMID: 2079019
- Korean J Nephrol.
- 1998 Sep;17(5):661-666.
Endothelial cell have been shown to play an active role in many phases of immunologic process, including binding of T lymphocytes, neutrophils, platelets, and monocytes to the endothelium, as well... -
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