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Polydeoxyribonucleotides Improve Diabetic Wound Healing in Mouse Animal Model for Experimental Validation

Kwon TR, Han SW, Kim JH, Lee BC, Kim JM, Hong JY, Kim BJ

BACKGROUND: Wound healing mechanisms is believed to have effects similar to wound healing disorders in diabetic patients, including abnormal inflammatory cells, angiogenesis disorders, and reduced collagen synthesis. Therefore, reestablishment of...
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Combination Treatment of Stereotactic Body Radiation Therapy and Immature Dendritic Cell Vaccination for Augmentation of Local and Systemic Effects

Choi CW, Jeong MH, Park YS, Son CH, Lee HR, Koh EK

PURPOSE: The purpose of this study was to investigate the efficacy of stereotactic body radiation therapy (SBRT) as a tumor-associated antigen (TAA) presentation method for dendritic cell (DC) sensitization and...
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Machine-Learning Based Automatic and Real-time Detection of Mouse Scratching Behaviors

Park I, Lee K, Bishayee K, Jeon HJ, Lee H, Lee U

Scratching is a main behavioral response accompanied by acute and chronic itch conditions, and has been quantified as an objective correlate to assess itch in studies using laboratory animals. Scratching...
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A Pilot Study to Evaluate the Efficacy and Safety of Treatment with Botulinum Toxin in Patients with Recalcitrant and Persistent Erythematotelangiectatic Rosacea

Park KY, Kwon HJ, Kim JM, Jeong GJ, Kim BJ, Seo SJ, Kim MN

BACKGROUND: There are few pharmacologic options to reduce erythema and flushing in patients with recalcitrant erythematotelangiectatic rosacea (ETR). We previously reported two cases of refractory flushing and erythema of rosacea...
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Symmetrical Drug-Related Intertriginous and Flexural Exanthema: Two Cases and Brief Literature Review

Seok J, Kim JM, Park KY, Seo SJ

It has been reported that there are a range of causative drugs related to symmetrical drug-related intertriginous and flexural exanthema (SDRIFE). The causative drugs reported so far include the following:...
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Intradermal Injection of Botulinum Toxin: A Safer Treatment Modality for Forehead Wrinkles

Jun JY, Park JH, Youn CS, Lee JH

Intramuscular injection of botulinum toxin A (BTXA) is commonly used for the treatment of forehead wrinkles. In practice, physicians often use an intradermal injection for this purpose, as they feel...
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Analysis of Current Status of the Community Health Nursing Practice Education

Cho YH, Do EY, Kang KS, Kim YM, Kim Y, Rou F, Lee CM, Choi IH, Choi HC

PURPOSE: The purpose of this study was to provide basic evidence to improve community health nursing practice education by analyzing the current status of actual operation, program outcomes and evaluation...
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Efficacy of Topical Tranexamic Acid in Treatment of Melasma

Yoo J, Ahn H, Kim MS, Jue MS, Choi KH

  • KMID: 2386238
  • Korean J Dermatol.
  • 2017 Jun;55(5):283-289.
BACKGROUND: Tranexamic acid (TXA), a plasmin inhibitor, has been used orally or via intradermal injection to treat melasma; however, there are limited studies regarding efficacy and safety of topical application...
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Histologic Evidence of New Collagen Formulation Using Platelet Rich Plasma in Skin Rejuvenation: A Prospective Controlled Clinical Study

Abuaf OK, Yildiz H, Baloglu H, Bilgili ME, Simsek HA, Dogan B

BACKGROUND: Platelet-rich plasma (PRP) is an autologous concentration of human platelets contained in a small volume of plasma and has recently been shown to accelerate rejuvenate aging skin by various...
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Effect of a Self-Evaluation Method Using Video Recording on Competency in Nursing Skills, Self-Directed Learning Ability, and Academic Self-Efficacy

Song SR, Kim YJ

PURPOSE: The purpose of this study was to evaluate the effect of a self-evaluation method using video recording on competency in nursing skills, self-directed learning ability, and academic self-efficacy in...
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Rejuvenating Effects of Facial Hydrofilling using Restylane Vital

Lee BM, Han DG, Choi WS

BACKGROUND: Morphological changes that accompany aging, such as wrinkles and skin laxity, are particularly prominent on facial skin. Recently, facial rejuvenation using the hydrofilling effect of hyaluronic acid (HA) filler...
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Systemic antibody response to nano-size calcium phospate biocompatible adjuvant adsorbed HEV-71 killed vaccine

Saeed MI, Omar AR, Hussein MZ, Elkhidir I, Sekawi Z

PURPOSE: Since 1980s, human enterovirus-71 virus (HEV-71) is one of the common infectious disease in Asian Pacific region since late 1970s without effective commercial antiviral or protective vaccine is unavailable...
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Effect of Botulinum Toxin A on Acute and Chronic Pain in Herpes Zoster Patients

Han G, Kim SH, Lee KS, Cho JW

  • KMID: 2301526
  • Korean J Dermatol.
  • 2014 Dec;52(12):845-850.
BACKGROUND: Many strategies are currently used to reduce herpes zoster pain, such as opioid analgesic administration and transcutaneous electrical nerve stimulation. However, a more effective and convenient method to reduce...
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Efficacy and Safety of Porcine Collagen Filler for Nasolabial Fold Correction in Asians: A Prospective Multicenter, 12 Months Follow-up Study

Lee JH, Choi YS, Kim SM, Kim YJ, Rhie JW, Jun YJ

Recently, injectable dermal fillers have become important alternatives to surgical procedures for the correction of facial wrinkles. Bovine collagen is the first approved material for filler injection, and several studies...
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A Phase III, Randomized, Double-Blind, Matched-Pairs, Active-Controlled Clinical Trial and Preclinical Animal Study to Compare the Durability, Efficacy and Safety between Polynucleotide Filler and Hyaluronic Acid Filler in the Correction of Crow's Feet: A New Concept of Regenerative Filler

Pak CS, Lee J, Lee H, Jeong J, Kim EH, Jeong J, Choi H, Kim B, Oh S, Kim I, Heo CY

The Rejuran(R) is a new filler product made from purified polynucleotides. Here we present data from an animal study and a clinical trial to examine the durability, efficacy and safety...
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Injectable Tissue-Engineered Soft Tissue for Tissue Augmentation

Rhee SM, You HJ, Han SK

Soft tissue augmentation is a process of implanting tissues or materials to treat wrinkles or soft tissue defects in the body. Over the years, various materials have evolved to correct...
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Effects of Injection Depth and Volume of Stabilized Hyaluronic Acid in Human Dermis on Skin Texture, Hydration, and Thickness

Kim J

BACKGROUND: Stabilized hyaluronic acid (S-HA) is used for soft tissue augmentation and can also be used for dermal hydration. According to previous reports, the injection volume of each shot is...
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Intradermal Therapy (Mesotherapy) for the Treatment of Acute Pain in Carpal Tunnel Syndrome: A Preliminary Study

Conforti G, Capone L, Corra S

BACKGROUND: The carpal tunnel syndrome (CTS) is the most common cause of severe hand pain. In this study we treated acute pain in CTS patients by means of local intradermal...
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Multiple Subcutaneous Abscesses Complicating Staphylococcus aureus Bacteremia associated with BCG Vaccination

Chae SH, Kim DH, Kim JW, Kim YT, Kim JB, Choi YJ, Park JS

  • KMID: 2317718
  • Soonchunhyang Med Sci.
  • 2013 Dec;19(2):133-135.
We report a case of 42-day-old girl with multiple abscesses in soft tissue sites and osteomyelitis caused by Staphylococcus aureus after an intradermal Bacillus Calmette-Guerin (BCG) vaccination. This may be...
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Long-term immunogenicity of the influenza vaccine at reduced intradermal and full intramuscular doses among healthy young adults

Song JY, Cheong HJ, Noh JY, Yang TU, Seo YB, Hong KW, Kim IS, Choi WS, Kim WJ

PURPOSE: To prepare for vaccine shortages under an influenza pandemic, several antigen-sparing strategies have been investigated. This study was aimed to evaluate the immunogenicity of influenza vaccine at reduced intradermal...
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