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Effects of sevoflurane on metalloproteinase and natural killer group 2, member D (NKG2D) ligand expression and natural killer cell-mediated cytotoxicity in breast cancer: an in vitro study

Kim HJ, Jeon S, Lee HJ, Bae J, Ri HS, Hong JM, Paek SI, Kwon SK, Kim JR, Park S, Yun EJ

Background: We investigated the effects of sevoflurane exposure on the expression of matrix metalloproteinase (MMP), expression and ablation of natural killer group 2, member D (NKG2D) ligands (UL16-binding proteins 1–3...
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Whole lung lavage with granulocyte macrophage colony-stimulating factor inhalation in children with pulmonary alveolar proteinosis: A case report

Kim S, Park MJ, Song KB, Choi EJ, Paek EY, Lee D, Hong SJ

Pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by hypoxemic respiratory failure due to the accumulation of lipoproteinaceous material in alveolar macrophages and alveoli. It has been reported...
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Effect of total intravenous versus inhalation anesthesia on long-term oncological outcomes in patients undergoing curative resection for early-stage non-small cell lung cancer: a retrospective cohort study

Seo KH, Hong JH, Moon MH, Hwang W, Lee SW, Chon JY, Kwon H, Hong SH, Kim S

Background: Propofol-based total intravenous anesthesia (TIVA) improves long-term outcomes after cancer surgery compared with inhalation anesthesia. However, its effect on patients undergoing non-small cell lung cancer (NSCLC) surgery remains unclear....
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Perioperative considerations of pyruvate dehydrogenase complex deficiency: a case report of two consecutive anesthesia

Lim WY, Lee HJ, Park EJ, Jeon S, Do W, Kim HJ, Lee D, Hong JM

Background: Pyruvate dehydrogenase complex (PDHC) deficiency is a rare mitochondrial disorder caused by a genetic mutation affecting the activity of the PDHC enzyme, which plays a major role in the...
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Corticosteroid outcome may be dependent of duration of use in severe COVID-19

Kim JH, Na YS, Lee SI, Moon YY, Hwang BS, Baek AR, Kim WY, Lee BY, Seong GM, Baek MS

Background/Aims: For patients hospitalized with coronavirus disease 2019 (COVID-19) who require supplemental oxygen, the evidence of the optimal duration of corticosteroid is limited. This study aims to identify whether long-term...
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Effect of sevoflurane-remifentanil and propofol-remifentanil anesthesia on glycocalyx shedding during deep inferior epigastric perforator flap breast reconstruction: a prospective randomized, controlled trial

Lee B, Shin HJ, Kweon KH, Kim NY

Background: The endothelial glycocalyx (EG) is an important structure that regulates vascular homeostasis. Deep inferior epigastric perforator (DIEP) flap is expected to cause substantial EG breakdown owing to the long...
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Salvage of a nasal chondrocutaneous flap after a traumatic avulsion injury using a combination of treatments polydeoxyribonucleotide injection, continuous non-rebreather mask oxygen therapy, and chemical leeching: a case report

Sun H, Kim MY, Kim JW

Skin avulsions are severe traumatic injuries, in which sections of skin and subcutaneous tissue are torn off from the body, and the surgical management and salvage of these injuries are...
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High-flow nasal cannula therapy for children with complex chronic disease in the general ward: A single, tertiary center experience

Lee BR, Kim MJ, Kim JH, Choi YJ, Park JS, Suh DI

Purpose: We aimed to evaluate the usefulness and safety of high-flow nasal cannula (HFNC) oxygen therapy in children with complex chronic diseases (CCD) with impending respiratory failure in the general...
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Acute inhalation toxicity assessment of 2-{2-[2-(4-nonylphenoxy)ethoxy]ethoxy}ethan-1-ol in Sprague-Dawley rats

Cho ES, Jang JY

The surfactant, 2-{2-[2-(4-nonylphenoxy)ethoxy]ethoxy}ethan-1-ol, is used in detergents, pesticides, cosmetics, and disinfectants. Since it is found in products that can be inhaled, we evaluated its toxicity to humans upon exposure. A...
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Chronic obstructive lung disease after ammonia inhalation burns: a report of two cases

Kim I, Lee H, Kang BH, Lee DH, Nam YH, Roh MS, Um SJ

Anhydrous ammonia is a commonly used chemical in industry. Ammonia gas inhalation causes thermal injuries and alkali burns in the airway and lung parenchyma. Previous case reports have stated that...
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Endotracheal intubation in rabbits using a video laryngoscope with a modified blade

Kim Y, Jeon HY, Yang I, Kim JH, Chung JH, Ju JH, Kim G, Park JW, Oh SY, Seong JK, Oh SH, Joo YS

Rabbits are being increasingly used as companion animals, and in research; thus, the need for proper veterinary care for rabbits has increased. Surgical access is more challenging in rabbits under...
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Inhalation injury after a landmine explosion: a case report

Kim W, Kim D, Jeong SY, Lee Y, Lee H

Blast injuries are divided into four classes, and inhalation injuries are a quaternary class of blast injuries. An inhalation injury can be critical to the patient due to the possibility...
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Foreign body aspirations in dental clinics: a narrative review

Huh JY

Foreign body aspiration can produce a medical emergency. Obstruction of the airways can be life-threatening, and complications may develop in less-severe cases if it is left untreated. Although it is...
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Oxygen Therapy in Cluster Headache, Migraine, and Other Headache Disorders

Mo H, Chung SJ, Rozen TD, Cho SJ

Oxygen therapy (OT) can relieve head pain in certain primary headache disorders, including cluster headache (CH). The exact underlying mechanism is currently uncertain, but suggested mechanisms include inhibition of the...
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Multi-Institute, Single Group, Prospective Observational Study to Evaluate the Efficacy of Mucomyst® in Relieving Symptoms of Globus Pharyngeus Refractory to Proton Pump Inhibitor

Park H, Park IS, Lee SH, Lee SW, Lee SJ, Lee BJ, Cheon YI, Park JO, Oh KH, Shin YS

Background and Objectives Globus pharyngeus is one of the most common symptoms of patients visiting otorhinolaryngology out-patient clinic, and usually long-lasting, difficult to treat, and frequently recurrent. Mucomyst®, N-acetyl cysteine...
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Review of Inhalation Health Risks Involving Chloromethylisothiazolinone (CMIT) and Methylisothiazolinone (MIT) Used as Disinfectants in Household Humidifiers

Kim J, Kim J, Park S, Park S, Zoh KE, Zoh KE, Park J, Park J, Choi S, Choi S, Hwang SH, Hwang SH, Lee SY, Lee SY, Park DU, Park DU

The association between lung injury and exposure to humidifier disinfectant (HD) containing a mixture of chloromethylisothiazolinone (CMIT) and methylisothiazolinone (MIT) has been controversial in South Korea. This study conducts a...
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Treatment of acute respiratory failure: high-flow nasal cannula

Park S

Background: High-flow nasal cannulas (HFNCs) have recently been used for several conditions, such as hypoxemic respiratory failure, hypercapnic respiratory failure, post-extubation respiratory failure, and preintubation oxygenation, in critically ill patients. Current...
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Association of Early Pubertal Onset in Female Rats With Inhalation of Lavender Oil

Kim YM, Lim HH

Background: Central precocious puberty (CPP) is caused by early activation of the hypothalamic–pituitary–gonadal axis but its major cause remains unclear. Studies have indicated an association between chronic environmental exposure to...
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In vitro acute inhalation toxicity for TiO2 (GST) using 3D human tissue model (EpiAirwayTM)

Jang SY, Park MK, Im JM, Park HS, Seo HS, Park HJ, Nah SS

The present study was performed to screen in vitro potential acute inhalation toxicity using an EpiAirwayTM tissue model (human tracheal/bronchial tissue) for the nano-sized titanium dioxide, GST manufactured as a...
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The Effect of the Timing of Dexamethasone Administration in Patients with COVID-19 Pneumonia

Lee HW, Park J, Lee JK, Park TY, Heo EY

Background: Despite the proven benefits of dexamethasone in hospitalized coronavirus disease 2019 (COVID-19) patients, the optimum time for the administration of dexamethasone is unknown. We investigated the progression of COVID-19...
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