- Diarrhea-predominant Irritable Bowel Syndrome-like Symptoms in Patients With Quiescent Crohn’s Disease: Comprehensive Analysis of Clinical Features and Intestinal Environment Including the Gut Microbiome, Organic Acids, and Intestinal Permeability
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Tomita T, Fukui H, Morishita D, Maeda A, Makizaki Y, Tanaka Y, Ohno H, Oshima T, Miwa H
- KMID: 2537945
- J Neurogastroenterol Motil.
- 2023 Jan;29(1):102-112.
- doi: 10.5056/jnm22027
Background/Aims Diarrhea-predominant irritable bowel syndrome (IBS-D)-like symptoms frequently occur in patients with quiescent Crohn’s disease (CD). To investigate the factors underlying IBS-D-like symptoms in patients with quiescent CD, we performed a... -
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- Recent Advances in ROS-Scavenging Metallic Nanozymes for Anti-Inflammatory Diseases: A Review
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Mohapatra A, Park IK
- KMID: 2538692
- Chonnam Med J.
- 2023 Jan;59(1):13-23.
- doi: 10.4068/cmj.2023.59.1.13
Oxidative stress and dysregulated inflammatory responses are the hallmarks of inflammatory disorders, which are key contributors to high mortality rates and impose a substantial economic burden on society. Reactive oxygen... -
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- Imbalance in the spinal serotonergic pathway induces aggravation of mechanical allodynia and microglial activation in carrageenan inflammation
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Jin J, Kang DH, Jeon J, Lee HG, Kim WM, Yoon MH, Choi JI
- KMID: 2537612
- Korean J Pain.
- 2023 Jan;36(1):51-59.
- doi: 10.3344/kjp.22297
Background: This study investigated the effect of an excess and a deficit of spinal 5-hydroxytryptamine (5-HT) on the mechanical allodynia and neuroglia activation in a rodent pain model of carrageenan... -
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- Loganin Prevents Hepatic Steatosis by Blocking NLRP3 Inflammasome Activation
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Jang JH, Yang G, Seok JK, Kang HC, Cho YY, Lee HS, Lee JY
- KMID: 2537579
- Biomol Ther.
- 2023 Jan;31(1):40-47.
- doi: 10.4062/biomolther.2022.077
Activation of the NLRP3 inflammasome is a necessary process to induce fibrosis in nonalcoholic fatty liver disease (NAFLD). Nonalcoholic steatohepatitis (NASH) is a kind of NAFLD that encompasses the spectrum... -
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- Effect of Activating Transcription Factor 3 on Inflammatory Response and Differentiation of Keratinocytes
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Kim K, Kim D, Shin JM, Hong D, Jung KE, Seo YJ, Lee Y, Kim CD
- KMID: 2538560
- Korean J Dermatol.
- 2022 Dec;60(10):640-646.
Background: Pathogenesis of psoriasis is related to dysregulated keratinocyte function and immune responses. Genetic background is one of the most important factors in disease pathogenesis. However, psoriasis-associated genes have not... -
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- Genetic diagnosis of systemic autoinflammatory diseases and underlying primary immunodeficiency
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Oh SH
- KMID: 2537687
- J Genet Med.
- 2022 Dec;19(2):57-62.
- doi: 10.5734/JGM.2022.19.2.57
Systemic autoinflammatory diseases (SAIDs) are characterized by unprovoked inflammatory episodes such as recurrent/periodic fever, serositis, skin lesions, abdominal symptoms, arthritis/arthralgia, and central nervous system involvement. Genetic diagnosis of SAIDs has... -
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- Stress-Induced Changes in Trophic Factor Expression in the Rodent Urinary Bladder: Possible Links With Angiogenesis
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Rijk MMd, Wolf-Johnston A, Kullmann AF, Maringer K, Sims-Lucas S, Koeveringe GAv, Rodríguez LV, Birder LA
- KMID: 2537306
- Int Neurourol J.
- 2022 Dec;26(4):299-307.
- doi: 10.5213/inj.2244118.059
Purpose: Substantive evidence supports a role of chronic stress in the development, maintenance, and even enhancement of functional bladder disorders such as interstitial cystitis/bladder pain syndrome (IC/BPS). Increased urinary frequency... -
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- Systematic Review and Meta-Analysis of Damage Associated Molecular Patterns HMGB1 and S100B in Schizophrenia
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Mackey M, Holleran L, Donohoe G, McKernan DP
- KMID: 2537380
- Psychiatry Investig.
- 2022 Dec;19(12):981-990.
- doi: 10.30773/pi.2022.0173
Objective Immune system dysregulation is hypothesised to be central to the aetiopathogenesis of schizophrenia; however, the role of sterile inflammation remains unclear. Damage associated molecular patterns are key initiators of... -
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- Effects of Perioperative Ketorolac Tromethamine on Intraocular Pressure in Glaucoma Patients Undergoing Cataract Surgery
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Joo S, Baek SU
- KMID: 2536853
- J Korean Ophthalmol Soc.
- 2022 Dec;63(12):984-993.
- doi: 10.3341/jkos.2022.63.12.984
Purpose: To identify the effects of 0.45% ketorolac tromethamine on intraocular pressure (IOP) after cataract surgery in glaucoma patients. Methods: A retrospective chart review of open angle glaucoma patients and controls... -
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- Immunologic Basis of Type 2 Biologics for Severe Asthma
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Sim S, Choi Y, Park HS
- KMID: 2538487
- Immune Netw.
- 2022 Dec;22(6):e45.
- doi: 10.4110/in.2022.22.e45
Asthma is a chronic airway inflammatory disease characterized by reversible airway obstruction and airway hyperreactivity to various environmental stimuli, leading to recurrent cough, dyspnea, and wheezing episodes. Regarding inflammatory mechanisms,... -
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- Chlorogenic acid attenuates pro‑inflammatory response in the blood of streptozotocin‑induced diabetic rats
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Lee Y, Bae C, Ahn T
- KMID: 2537636
- Lab Anim Res.
- 2022 Dec;38(4):329-336.
- doi: 10.1186/s42826-022-00148-x
Background: Chlorogenic acid (CGA) has been shown to reduce pro-inflammation by scavenging reactive oxy‑ gen species (ROS) and reactive nitrogen species. In this study, the anti-inflammatory effect of CGA was... -
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- Updates on Intra-articular Corticosteroid Injection for the Treatment of Adhesive Capsulitis
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Oh JH, Jung IH, Park EW, Cho JH
- KMID: 2536896
- Keimyung Med J.
- 2022 Dec;41(2):51-55.
- doi: 10.46308/kmj.2022.00108
Adhesive capsulitis of the shoulder joint is a common disorder characterized by a gradual increase of pain and limitation in range of motion of the shoulder joint. The pathophysiological process... -
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- L-Theanine-Treated Adipose-Derived Mesenchymal Stem Cells Alleviate the Cytotoxicity Induced by N-Nitrosodiethylamine in Liver
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Lai YJ, Sung YT, Lai YA, Chen LN, Chen TS, Chien CT
- KMID: 2536452
- Tissue Eng Regen Med.
- 2022 Dec;19(6):1207-1221.
- doi: 10.1007/s13770-022-00472-2
BACKGROUND: Liver inflammation is the main cause of severe liver diseases, including liver fibrosis, steatohepatitis, cirrhosis and hepatocellular carcinoma. Cell therapy topics are receiving increasingly more attention. The therapeutic applications... -
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- Human Fetal Cartilage-Derived Progenitor Cells Exhibit AntiInflammatory Effect on IL-1β-Mediated Osteoarthritis Phenotypes In Vitro
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Kim J, Tran ANT, Lee JY, Park SH, Park SR, Min BH, Choi BH
- KMID: 2536455
- Tissue Eng Regen Med.
- 2022 Dec;19(6):1237-1250.
- doi: 10.1007/s13770-022-00478-w
BACKGROUND: In this study, we have investigated whether human fetal cartilage progenitor cells (hFCPCs) have antiinflammatory activity and can alleviate osteoarthritis (OA) phenotypes in vitro. METHODS: hFCPCs were stimulated with various... -
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- Dexmedetomidine attenuates subarachnoid hemorrhage-induced acute lung injury through regulating autophagy and TLR/NFκB signaling pathway
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Han DW, Oh JE, Lim BJ, Han Y, Song Y
- KMID: 2536123
- Korean J Anesthesiol.
- 2022 Dec;75(6):518-529.
- doi: 10.4097/kja.22165
Background: Acute lung injury (ALI) is the most serious complication of subarachnoid hemorrhage (SAH). We investigated role of autophagy and inflammatory signaling pathways in lung damage and therapeutic effects of... -
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- L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats
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Wang Z, Liang M, Li H, Liu B, Yang L
- KMID: 2536507
- Nutr Res Pract.
- 2022 Dec;16(6):729-744.
- doi: 10.4162/nrp.2022.16.6.729
BACKGROUND/OBJECTIVES: 4-Hydroxy-2-nonenal (HNE) is a biomarker for oxidative stress to induce inflammation. Methionine is an essential sulfur-containing amino acid with antioxidative activity. On the other hand, the evidence on whether... -
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- Differential effects of various dietary proteins on dextran sulfate sodiuminduced colitis in mice
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Ahn E, Jeong H, Kim E
- KMID: 2536505
- Nutr Res Pract.
- 2022 Dec;16(6):700-715.
- doi: 10.4162/nrp.2022.16.6.700
BACKGROUND/OBJECTIVES: Chronic colitis is a risk factor for colorectal cancer (CRC) development in both animals and humans. Previously, we reported that a diet rich in protein (with casein as the... -
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- Myricetin prevents sleep deprivation-induced cognitive impairment and neuroinflammation in rat brain via regulation of brain-derived neurotropic factor
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Sur B, Lee B
- KMID: 2534518
- Korean J Physiol Pharmacol.
- 2022 Nov;26(6):415-425.
- doi: 10.4196/kjpp.2022.26.6.415
Memory formation in the hippocampus is formed and maintained by circadian clock genes during sleep. Sleep deprivation (SD) can lead to memory impairment and neuroinflammation, and there remains no effective... -
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- A Novel Therapeutic Effect of a New Variant of CTLA4-Ig with Four Antennas That Are Terminally Capped with Sialic Acid in the CTLA4 Region
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Piao Y, Yun SY, Kim HS, Park BK, Ha HC, Fu Z, Jang JM, Back MJ, Shin IC, Won JH, Kim DK
- KMID: 2534702
- Biomol Ther.
- 2022 Nov;30(6):529-539.
- doi: 10.4062/biomolther.2022.071
Rheumatoid arthritis (RA) is a multifactorial immune-mediated disease, the pathogenesis of which involves different cell types. T-cell activation plays an important role in RA. Therefore, inhibiting T-cell activation is one... -
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- Inflammatory Polyneuropathy Associated with Myelodysplastic Syndrome
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Hong SW, Kim HR, Ahn SW
- KMID: 2535877
- J Korean Neurol Assoc.
- 2022 Oct;40(4):338-342.
- doi: 10.17340/jkna.2022.4.11
Inflammatory polyneuropathy may be associated with various tumorous diseases, including hematological malignancy. A 50-year-old man visited neurologic department complaining of bilateral lower extremities weakness, tingling sensation and weight loss. Initially... -
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