- Adenosine Blockage in Tumor Microenvironment and Improvement of Cancer Immunotherapy
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Arab S, Hadjati J
- KMID: 2455933
- Immune Netw.
- 2019 Aug;19(4):e23.
- doi: 10.4110/in.2019.19.e23
Immunotherapy has been introduced into cancer treatment methods, but different problems have restricted the efficacy of these protocols in clinical trials such as the presence of various immunomodulatory factors in... -
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- Extrinsic Acquisition of CD80 by Antigen-Specific CD8⺠T Cells Regulates Their Recall Immune Responses to Acute Viral Infection
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Son J, Ha SJ
- KMID: 2455935
- Immune Netw.
- 2019 Aug;19(4):e25.
- doi: 10.4110/in.2019.19.e25
CD80 is mainly expressed on Ag-presenting cells (APCs) as a costimulatory molecule but is also detected on T cells. However, the origin and physiological role of CD80 on CD8⺠T... -
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- Emerging Themes for the Role of Antibodies in Tuberculosis
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Tran AC, Kim MY, Reljic R
- KMID: 2455934
- Immune Netw.
- 2019 Aug;19(4):e24.
- doi: 10.4110/in.2019.19.e24
The best way to debunk a scientific dogma is to throw irrefutable evidence at it. This is especially true if the dogma in question has been nurtured over many decades,... -
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- Downregulation of IL-18 Expression in the Gut by Metformin-induced Gut Microbiota Modulation
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Lee H, Kim J, An J, Lee S, Choi D, Kong H, Song Y, Park IH, Lee CK, Kim K
- KMID: 2455938
- Immune Netw.
- 2019 Aug;19(4):e28.
- doi: 10.4110/in.2019.19.e28
IL-18 is a crucial pro-inflammatory cytokine that mediates chronic intestinal inflammation. Metformin, an anti-diabetic drug, was reported to have ameliorative effects on inflammatory bowel disease. Recently, the mechanism of action... -
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- Evaluation of Protective Immunity of Peptide Vaccines Composed of a 15-mer N-terminal Matrix Protein 2 and a Helper T-Cell Epitope Derived from Influenza A Virus
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Kim JK, Cheong S, Lee MK
- KMID: 2455939
- Immune Netw.
- 2019 Aug;19(4):e29.
- doi: 10.4110/in.2019.19.e29
The matrix protein 2 of influenza A virus (IFAV) has a relatively conserved ectodomain (M2e) composed of 23 amino acids, and M2e-based vaccines have been suggested to induce broad protective... -
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- Circulating CCR7(lo)PD-1(hi) Follicular Helper T Cells Indicate Disease Activity and Glandular Inflammation in Patients with Primary Sjögren's Syndrome
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Kim JW, Lee J, Hong SM, Lee J, Cho ML, Park SH
- KMID: 2455936
- Immune Netw.
- 2019 Aug;19(4):e26.
- doi: 10.4110/in.2019.19.e26
Since primary Sjögren's syndrome (pSS) is an autoummune disease of B cell hyperactivity and pathologic autoantibody response, follicular helper T (Tfh) cells and follicular regulatory T (Tfr) cells are suggested... -
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- Intravenous Immunoglobulin Controls Th17 Cell-Mediated Osteoclastogenesis
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Kim KW, Kim HR, Kim BM, Won JY, Lee KA, Lee SH
- KMID: 2455937
- Immune Netw.
- 2019 Aug;19(4):e27.
- doi: 10.4110/in.2019.19.e27
The purpose of this study was to determine the regulatory role of intravenous Ig (IVIg) in Th17 cytokine–induced RANK ligand (RANKL) expression and osteoclast (OC) differentiation from OC precursors (pre-OC).... -
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