- Role of Innate Immunity in Diabetes and Metabolism: Recent Progress in the Study of Inflammasomes
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Lee MS
- KMID: 2150696
- Immune Netw.
- 2011 Apr;11(2):95-99.
- doi: 10.4110/in.2011.11.2.95
Type 1 diabetes is one of the classical examples of organ- specific autoimmune diseases characterized by lymphocytic infiltration or inflammation in pancreatic islets called 'insulitis'. In contrast, type 2 diabetes... -
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- Mycobacterial Heparin-binding Hemagglutinin Antigen Activates Inflammatory Responses through PI3-K/Akt, NF-kappaB, and MAPK Pathways
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Kim KH, Yang CS, Shin AR, Jeon SR, Park JK, Kim HJ, Jo EK
- KMID: 2150700
- Immune Netw.
- 2011 Apr;11(2):123-133.
- doi: 10.4110/in.2011.11.2.123
BACKGROUND: Mycobacterium tuberculosis (Mtb) heparin binding hemagglutinin (HBHA) is an Ag known to evoke effective host immune responses during tuberculosis infection. However, the molecular basis of the host immune response... -
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- Characterization of Monoclonal Antibodies against Human Leukocyte Common Antigen (CD45)
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Shin HM, Cho WD, Lee GK, Lee SH, Lee KM, Ji GY, Yoon SS, Koo JH, Lee HC, Lee KH, Song HG
- KMID: 2150699
- Immune Netw.
- 2011 Apr;11(2):114-122.
- doi: 10.4110/in.2011.11.2.114
BACKGROUND: The leukocyte common antigen (CD45) is a transmembrane-type protein tyrosine phosphatase that has five isoforms. METHODS: We generated seven murine mAbs against human CD45 by injecting cells from different origins,... -
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- Characterization of CTL Clones Specific for Single Antigen, H60 Minor Histocompatibility Antigen
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Jeon JY, Jung KM, Chang J, Choi EY
- KMID: 2150697
- Immune Netw.
- 2011 Apr;11(2):100-106.
- doi: 10.4110/in.2011.11.2.100
BACKGROUND: Disparities of Minor H antigens can induce graft rejection after MHC-matched transplantation. H60 has been characterized as a dominant antigen expressed on hematopoietic cells and considered to be an... -
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- Dietary Aloe Reduces Adipogenesis via the Activation of AMPK and Suppresses Obesity-related Inflammation in Obese Mice
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Shin E, Shin S, Kong H, Lee S, Do SG, Jo TH, Park YI, Lee CK, Hwang IK, Kim K
- KMID: 2150698
- Immune Netw.
- 2011 Apr;11(2):107-113.
- doi: 10.4110/in.2011.11.2.107
BACKGROUND: Metabolic disorders, including type II diabetes and obesity, present major health risks in industrialized countries. AMP-activated protein kinase (AMPK) has become the focus of a great deal of attention... -
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