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A 24-Year-Old Woman Presenting with Decreased Visual Acuity and Pain on Left Eye

Hyun JW, Kim HJ

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Effect of Combined Intravenous Immunoglobulin and Mycophenolate Mofetil in a Pediatric Patient With Highly Relapsing Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease

Kim KH, Hyun JW, Kim HJ, Kim SH

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Erratum to: High Seroprevalence and Index of Anti-John-Cunningham Virus Antibodies in Korean Patients with Multiple Sclerosis

Kim SH, Kim Y, Jung JY, Park NY, Jang H, Hyun JW, Kim HJ

The authors hope to add the Acknowledgements, which have been omitted from the initial manuscript. Also, the authors hope to revise the Conflict of Interest.
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Adult Onset Still's Disease

Lee DH, Park JW, Hyun JW, Kim DH, Suh YS

  • KMID: 2294530
  • J Korean Acad Fam Med.
  • 2007 Mar;28(3):210-213.
Adult onset Still's disease (AOSD) is an uncommon acute systemic inflammatory disease of unknown origin. The clinical features include high spiking fever, arthralgia or arthritis, transient maculopapular rash, lymphadenopathy, hepatosplenomegaly,...
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The Polyphenol Chlorogenic Acid Attenuates UVB-mediated Oxidative Stress in Human HaCaT Keratinocytes

Cha JW, Piao MJ, Kim KC, Yao CW, Zheng J, Kim SM, Hyun CL, Ahn YS, Hyun JW

  • KMID: 2170653
  • Biomol Ther.
  • 2014 Mar;22(2):136-142.
We investigated the protective effects of chlorogenic acid (CGA), a polyphenol compound, on oxidative damage induced by UVB exposure on human HaCaT cells. In a cell-free system, CGA scavenged 1,1-diphenyl-2-picrylhydrazyl...
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Fusarium Fruit Rot of Citrus in Jeju Island

Hyun JW, Lee SC, Kim DH, Ko SW, Kim KS

  • KMID: 2312324
  • Mycobiology.
  • 2000 Sep;28(3):158-162.
Twenty-three isolates of Fusarium spp. were obtained from decayed citrus fruits in the fields and storages in 1998-1999. Of them, six and five isolates belonged to F. proliferatum and F....
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Shikonin Exerts Cytotoxic Effects in Human Colon Cancers by Inducing Apoptotic Cell Death via the Endoplasmic Reticulum and Mitochondria-Mediated Pathways

Han X, Kang KA, Piao MJ, Zhen AX, Hyun YJ, Kim HM, Ryu YS, Hyun JW

The apoptotic effects of shikonin (5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-enyl]naphthalene-1,4-dione) on the human colon cancer cell line SNU-407 were investigated in this study. Shikonin showed dose-dependent cytotoxic activity against SNU-407 cells, with an estimated...
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Clinical and Radiological Features of Myelin Oligodendrocyte Glycoprotein-Associated Myelitis in Adults

Kim KH, Kim SH, Hyun JW, Kim HJ

Antibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) have recently been established as a biomarker for MOG-antibody-associated disease (MOGAD), which is a distinct demyelinating disease of the central nervous system. Among the...
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Sleep Related Disorders and Inflammatory Diseases of the Central Nervous System

Hyun JW, Kim SH, Kim HJ

Multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) are inflammatory diseases of the central nervous system and inflammatory conditions involving sleep-related anatomical structures, associated with sleep-related disorders. After the...
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Two Cases of Cerebral Infarctions from Vertebral Artery Dissection Induced by Severe Coughing

Hyun JW, Cho HJ

  • KMID: 2288701
  • Korean J Stroke.
  • 2012 Dec;14(3):152-155.
Vertebral artery dissection (VAD) is a rare cause of young age stroke. This risky condition can be caused by even minor head or neck trauma. None of the previous studies...
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7,8-Dihydroxyflavone Protects High Glucose-Damaged Neuronal Cells against Oxidative Stress

Cho SJ, Kang KA, Piao MJ, Ryu YS, Fernando P, Zhen AX, Hyun YJ, Ahn MJ, Kang HK, Hyun JW

Oxidative stress is considered a major contributor in the pathogenesis of diabetic neuropathy and in diabetes complications, such as nephropathy and cardiovascular diseases. Diabetic neuropathy, which is the most frequent...
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Galangin (3,5,7-Trihydroxyflavone) Shields Human Keratinocytes from Ultraviolet B-Induced Oxidative Stress

Madduma Hewage SRK, Piao MJ, Kim KC, Cha JW, Han X, Choi YH, Chae S, Hyun JW

Most skin damage caused by ultraviolet B (UVB) radiation is owing to the generation of reactive oxygen species. Phytochemicals can act as antioxidants against UVB-induced oxidative stress. This study investigated...
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Purpurogallin Protects Keratinocytes from Damage and Apoptosis Induced by Ultraviolet B Radiation and Particulate Matter 2.5

Zhen AX, Piao MJ, Hyun YJ, Kang KA, Ryu YS, Cho SJ, Kang HK, Koh YS, Ahn MJ, Kim TH, Hyun JW

Purpurogallin, a natural phenol obtained from oak nutgalls, has been shown to possess antioxidant, anticancer, and anti-inflammatory effects. Recently, in addition to ultraviolet B (UVB) radiation that induces cell apoptosis...
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6'-O-Galloylpaeoniflorin Protects Human Keratinocytes Against Oxidative Stress-Induced Cell Damage

Yao CW, Piao MJ, Kim KC, Zheng J, Cha JW, Hyun JW

  • KMID: 2048305
  • Biomol Ther.
  • 2013 Sep;21(5):349-357.
6'-O-galloylpaeoniflorin (GPF) is a galloylated derivate of paeoniflorin and a key chemical constituent of the peony root, a perennial flowering plant that is widely used as an herbal medicine in...
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The Systemic Rheumatologic Disease and Neuromyelitis Optica

Hyun JW, Kim SH, Kim HJ

Neuromyelitis optica (NMO), an autoimmune inflammatory disease of the central nervous system (CNS), is related with autoantibodies for aquaporin-4, which is the most abundant water channel in CNS. The clinical...
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Baicalein Inhibits αα-Melanocyte-stimulating Hormonestimulated Melanogenesis via p38 Mitogen-activated Protein Kinase Pathway in B16F10 Mouse Melanoma Cells

Oh MC, Madushan Fernando PDS, Piao MJ, Kang KA, akmini Herath HMU, Hyun JW

Excessive UVB exposure causes development of both malignant and non-malignant melanoma via the secretion of α-melanocyte-stimulating hormone (α-MSH). We investigated whether baicalein (5,6,7-trihydroxyflavone) could inhibit α-MSH-stimulated melanogenesis. Baicalein prevented UVB-...
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A Benzylideneacetophenone Derivative Induces Apoptosis of Radiation-Resistant Human Breast Cancer Cells via Oxidative Stress

Park JE, Piao MJ, Kang KA, Shilnikova K, Hyun YJ, Oh SK, Jeong YJ, Chae S, Hyun JW

Benzylideneacetophenone derivative (1E)-1-(4-hydroxy-3-methoxyphenyl) hept-1-en-3-one (JC3) elicited cytotoxic effects on MDA-MB 231 human breast cancer cells-radiation resistant cells (MDA-MB 231-RR), in a dose-dependent manner, with an IC₅₀ value of 6 μM...
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Fucodiphlorethol G Purified from Ecklonia cava Suppresses Ultraviolet B Radiation-Induced Oxidative Stress and Cellular Damage

Kim KC, Piao MJ, Zheng J, Yao CW, Cha JW, Kumara MH, Han X, Kang HK, Lee NH, Hyun JW

  • KMID: 2170623
  • Biomol Ther.
  • 2014 Jul;22(4):301-307.
Fucodiphlorethol G (6'-[2,4-dihydroxy-6-(2,4,6-trihydroxyphenoxy)phenoxy]biphenyl-2,2',4,4',6-pentol) is a compound purified from Ecklonia cava, a brown alga that is widely distributed offshore of Jeju Island. This study investigated the protective effects of fucodiphlorethol G...
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Intravenous t-PA Thrombolysis in an Acute Ischemic Stroke Patient With Takayasu's Arteritis

Cho HJ, Hyun JW, Park KD, Oh JY

  • KMID: 2137917
  • J Korean Neurol Assoc.
  • 2011 May;29(2):116-119.
The usefulness of intravenous tissue plasminogen activator (IVT) in patients with acute ischemic stroke related to Takayasu's arteritis (TA) has not been documented; it is not recommended due to the...
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Aurora Kinase A Is a Prognostic Marker in Colorectal Adenocarcinoma

Koh HM, Jang BG, Hyun CL, Kim YS, Hyun JW, Chang WY, Maeng YH

BACKGROUND: Aurora kinase A (AURKA), or STK15/BTAK, is a member of the serine/threonine kinase family and plays important roles in mitosis and chromosome stability. This study investigated the clinical significance...
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