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Clinical Features and Prognostic Factors of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Multicenter Retrospective Study of Data from 88 Patients

Hong JY, Chung EH, Yang NG, Kim JY, Heo NH, Lee SH, Kim JE, Lee SY

  • KMID: 2520798
  • Korean J Dermatol.
  • 2021 Sep;59(8):604-610.
Background: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are potentially fatal acute hypersensitivity reactions that involve the skin and mucous membranes. Because they are relatively rare diseases, it is...
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Prediction of Food Allergens Sensitization Based on History Taking Technique in Young Children

Lee J, Jeong K, Lee E, Lee S

Background: The diagnosis of food allergies needs to be confirmed through an oral food challenge (OFC). However, specific immunoglobulin E (sIgE) concentrations analyzed by serological tests are also helpful in...
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Immunogloboulin E-Mediated Food Sensitization in Children with Celiac Disease: A Single-Center Experience

Cudowska B, Lebensztejn DM

Purpose Celiac disease (CD) is an autoimmune disorder of the small intestine caused by an abnormal immune response to gluten proteins and is often characterized by gastrointestinal symptoms. Food allergy (FA)...
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Diagnosis and Management of Antibiotic Allergies

Kim JH

Drug allergies encompass a spectrum of immune-mediated hypersensitivity reactions with various mechanisms and clinical presentations. β-lactam drugs are common causes of drug allergies. A detailed clinical history as well as...
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Food allergies and food-induced anaphylaxis: role of cofactors

shin M

Food allergies and food-induced anaphylaxis are important health problems. Several cofactors modulating the onset of anaphylaxis have been identified. In the presence of cofactors, allergic reactions may be induced at...
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Diagnosis of Hypersensitivity Pneumonitis: 2020 Clinical Practice Guideline

Park S, Oh YW, Kang EY, Yong HS, Kim C, Lee KY, Hwang SH

Hypersensitivity pneumonitis (HP) is an interstitial lung disease (ILD) characterized by an inhaled inciting antigen that leads to the inflammation of the lung parenchyma and small airway with immunologic reactions....
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A single nonsteroidal anti-inflammatory drugs-induced anaphylaxis to diclofenac confirmed by skin testing

Lee J

Nonsteroidal anti-inflammatory drugs (NSAIDs) are a major culprit of drug-induced hypersensitivity. No reliable diagnostic tests other than a direct challenge are available. Cross-reactivity among NSAIDs that inhibit cyclooxygenase-1 is common....
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Growth in Infants with Cow's Milk Protein Allergy Fed an Amino AcidBased Formula

Vandenplas Y, Dupont C, Eigenmann P, Heine RG, Høst A, Järvi A, Kuitunen M, Mukherjee R, Ribes-Koninckx C, Szajewska H, Berg Av, Zhao ZY, on behalf of the Mosaic Study Investigator Group

Purpose: The present study assessed the role of an amino acid-based formula (AAF) in the growth of infants with cow's milk protein allergy (CMPA). Methods: Non-breastfed, term infants aged 0–6 months...
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Retrospective and Prospective Determination of the Cow's MilkRelated Symptom Score (CoMiSS™) Values in Symptomatic Infants

Kozłowska-Jalowska A, Horvath A, Vandenplas Y, Szajewska H

Purpose: The Cow's Milk-related Symptom Score (CoMiSS™) was developed as an awareness tool for evaluating cow's milk-related symptoms in otherwise healthy children. Using a convenience sample of participants, this cross-sectional...
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Role of Krebs von den Lungen-6 (KL-6) in Assessing Hypersensitivity Pneumonitis

Mostafa AI, Salem AE, Ahmed HAM, Bayoumi AI, Halim RMA, Samie RMA

Background: Hypersensitivity pneumonitis (HP) is an increasingly recognized form of diffuse parenchymal lung disease. Krebs von den Lungen-6 (KL-6) is now classified as a human MUC1 mucin protein, and regenerating...
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Growth Patterns of Indonesian Infants with Cow's Milk Allergy and Fed with Soy-Based Infant Formula

Setiabudiawan B, Sitaresmi MN, Sapartini G, S, Citraresmi E, Sekartini R, Putra AM, Jo J

Purpose: The use of soy-based infant formula has increased widely in infants with cow's milk allergy (CMA). This study aimed to provide evidence on the growth pattern of CMA infants...
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Age Differences in Pet Sensitization by Pet Ownership

Won JY, Kwon JW, Hong SN, Lee WH

Objectives. The association between pet sensitization and pet ownership remains unclear. Therefore, we aimed to elucidate the association between pet sensitization and pet ownership by age. Methods. We retrospectively reviewed 2,883...
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Tooth hypersensitivity associated with paresthesia after inferior alveolar nerve injury: case report and related neurophysiology

You TM

Inferior alveolar nerve (IAN) injury is usually caused by stretching or crushing of the neurovascular structures and postoperative intra-alveolar hematoma or edema after dental procedures. This results in paresthesia in...
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Hypersensitivity Reactions to Contrast Media Used in Computed Tomography in Korea

Kang HJ, Lee KH, Park CJ

  • KMID: 2514432
  • Korean J Dermatol.
  • 2021 Mar;59(3):212-216.
Background: Contrast media have been widely used for the diagnosis of numerous diseases. Although they are generally safe, the reported number of hypersensitivity reactions to contrast media has increased annually. Objective:...
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Current practice for diagnosing immediate drug hypersensitivity reactions in Korea

Kang SY, Yang MS, Song WJ, Cho SH

Background/Aims: Skin (STs) and drug provocation (DPTs) tests are essential for identifying the culprit drugs causing drug hypersensitivity reactions (DHRs). Several protocols have been developed for the identification of some...
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Beta-Lactam Allergy: Real Practice in a Regional Hospital

Kim H, Lee J, Kim S

Background/Aims: Beta-lactam (BL) antibiotics are widely prescribed for controlling bacterial infections and relevant culprits of adverse drug reactions (ADRs). BL allergy may vary according to prescription patterns within a given...
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Management of patients with allergy to local anesthetics: two case reports

Arya V, Arora G, Kumar S, Kaur A, Mishra S

Lidocaine is the most commonly used local anesthetic (LA) agent in various dental as well as oral and maxillofacial procedures. Although rare, adverse effects and allergic reactions to lidocaine have...
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Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome in liver transplantation

Cho A, Lee JM, Hong K, Han ES, Hong SK, Choi Y, Yi NJ, Lee KW, Suh KS

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare delayed-type hypersensitivity reaction that causes skin abnormalities and mucosal involvement of the entire body. This is a case...
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A Pathophysiological Perspective on COVID-19's Lethal Complication: From Viremia to Hypersensitivity Pneumonitis-like Immune Dysregulation

Sanchez-Gonzalez MA, Moskowitz D, Issuree PD, Yatzkan G, Rizvi SA, Day K

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the coronavirus responsible for our recent coronavirus disease 2019 pandemic, is driving a lung immunopathology that strongly resembles a severe form of hypersensitivity...
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Dasatinib Inhibits Lyn and Fyn Src-Family Kinases in Mast Cells to Suppress Type I Hypersensitivity in Mice

Lee D, Park YH, Lee JE, Kim HS, Min KY, Jo MG, Kim HS, Choi WS, Kim YM

Mast cells (MCs) are systemically distributed and secrete several allergic mediators such as histamine and leukotrienes to cause type I hypersensitivity. Dasatinib is a type of anti-cancer agent and it...
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