- Electroacupuncture on Visceral Hyperalgesia - What Is Its Mechanism?
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Shin JE
- KMID: 2326155
- J Neurogastroenterol Motil.
- 2010 Jul;16(3):230-231.
No abstract available. -
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- Opioid-induced hyperalgesia is a paradox for perioperative physician
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Lee H
- KMID: 2236225
- Korean J Anesthesiol.
- 2013 Jan;64(1):1-2.
- doi: 10.4097/kjae.2013.64.1.1
No abstract available. -
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- L - NAME Inhibits Hyperalgesia Induced by Freund's Complete Adjuvant in Rat Paw
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Leem JW, Choi Y, Lee C, Song MH, Lee DM, Raja SN
- KMID: 2425666
- J Korean Pain Soc.
- 1998 Oct;11(2):194-200.
BACKGROUND: Effect of nitric oxide on the hyperalgesia induced by inflammation is controversial. We attempted to find out the peripheral effects of nitric oxide (NO) on hyperalgesia induced by Freund's eomplete... -
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- The Mechanism of Contralateral Hyperalgesia in the Persistent Muscle Pain Rat Model
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Sohn MK, Kang SK, Lee SH, Han SM
- KMID: 2002646
- J Korean Acad Rehabil Med.
- 2004 Oct;28(5):477-482.
OBJECTIVE: This study was designed to investigate the mechanism of the primary afferent input to spread of contralateral hyperalgesia in the persistent muscle pain model in the rat. METHOD: Muscle... -
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- Role of Spinal Microglia in Visceral Hyperalgesia and NK1R Up-Regulation in a Rat Model of Chronic Stress (Gastroenterology 2009;136:1339-1348)
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Hong SJ
- KMID: 2326128
- J Neurogastroenterol Motil.
- 2010 Jan;16(1):101-103.
No abstract available. -
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- Steroid on Hyperalgesia in Nerve Ligation Induced Neuropathic Pain Rat Model
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Kim TK, Kim YS, Kim MG
- KMID: 2032620
- Korean J Anesthesiol.
- 2004 Dec;47(6):S14-S17.
- doi: 10.4097/kjae.2004.47.6.S14
BACKGROUND: Neuropathic pain is resistant to conventional treatments, and may seriously affect the quality of life. Insufficient has been done on drug combination for the treatment of neuropathic pain. So... -
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- Repeated Intraplantar Injection of Low-pH Saline Produce Mechanical Hyperalgesia in Rat
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Woo YC
- KMID: 2104839
- J Korean Pain Soc.
- 2004 Dec;17(2):113-118.
- doi: 10.3344/jkps.2004.17.2.113
BACKGROUND: The purpose of this study was to characterize an animal model of persistent mechanical hyperalgesia induced by repeated intraplantar injection of low pH saline. METHODS: Saline, at pHs of... -
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- Opioid-induced hyperalgesia
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Lee H
- KMID: 2194833
- J Korean Med Assoc.
- 2014 Jan;57(1):41-46.
- doi: 10.5124/jkma.2014.57.1.41
Perioperative opioid-induced hyperalgesia (OIH) can be defined as the "increased perception of pain after opioid-based anesthesia and surgery" since hyperalgesia is defined as "increased pain from a stimulus that normally... -
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- Effects of L-NAME on the Mechanical Hyperalgesia after the Development of Inflammation by Freund's Complete Adjuvant in Rat Paw
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Kim MK, Choi Y, Kong HS, Leem JW, Leem HS, Chung SJ, Lee C
- KMID: 1946736
- J Korean Pain Soc.
- 1999 Nov;12(2):171-176.
BACKGROUND: Effect of nitric oxide on the hyperalgesia induced by inflammation is controversial. From our previous experiment, NOS inhibitor, L-NAME given during the induction period decrease mechanical hyperalgesia occurred by Freund's complete... -
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- Opioid induced hyperalgesia in anesthetic settings
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Lee HJ, Yeomans DC
- KMID: 2039524
- Korean J Anesthesiol.
- 2014 Nov;67(5):299-304.
- doi: 10.4097/kjae.2014.67.5.299
Pain is difficult to investigate and difficult to treat, in part, because of problems in quantification and assessment. The use of opioids, combined with classic anesthetics to maintain hemodynamic stability... -
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- Carrageenan-Induced Hyperalgesia Is Partially Alleviated by Endomorphin-1 Locally Delivered into Inflamed Paws In Rat
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Lee SE, Shin HK
- KMID: 1607523
- Korean J Physiol Pharmacol.
- 2003 Dec;7(6):369-373.
This study was performed to test whether endomorphin-1 has analgesic effect, when locally administrated into inflamed peripheral tissue. Carrageenan suspension (0.5%) was injected intraplantarly into the right paw of Sprague-Dawley... -
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- Two Cases of Opioid-Induced Hyperalgesia in Cancer Patients Treated with Opioids for Pain Management
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Hong S, Kwon JH, Han SJ
- KMID: 2450254
- Korean J Hosp Palliat Care.
- 2019 Jun;22(2):100-104.
- doi: 10.0000/kjhpc.2019.22.2.100
Opioids are important drugs for the management of severe cancer pain without a ceiling effect. However, opioid administration leads to dose-limiting complications including drowsiness, hallucinations, delirium, respiratory depression, cognitive impairment,... -
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- Effects of Substance P Antagonist, [D-Arg, D-Phe, D-Trp, Leu]- Substance P on the Mechanical Hyperalgesia of Inflammation Induced by Freund's Complete Adjuvant in Rat Paw
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Kim MK, Choi Y, Kong HS, Leem JW, Yang HC, Chung SJ, Hwang SJ, Hwang JH
- KMID: 2091504
- Korean J Anesthesiol.
- 2000 Jan;38(1):158-163.
- doi: 10.4097/kjae.2000.38.1.158
BACKGROUND: The effect of substance P (SP) on the hyperalgesia induced by inflammation is controversial, and as SP remains in the periphery just for a short period of time after... -
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- Development and Assessment of Animal Model of Persistent Muscle Pain
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Sohn MK, Lee KY, Yang SS, Lee SH, Kim SS
- KMID: 2323919
- J Korean Acad Rehabil Med.
- 2003 Oct;27(5):757-763.
OBJECTIVE: The purposes of this study were the development and assessment of an animal model of persistent muscle pain induced by repeated intramuscular injections of low pH buffered saline. METHOD:... -
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- Mechanism of Hyperalgesia Following Cutaneous Inflammation by Complete Freund Adjuvant
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Jeong Y, Leem JW, Chung SS, Kim YS, Yoon DM, Nam TS, Paik KS
- KMID: 2335903
- J Korean Pain Soc.
- 2000 Nov;13(2):164-174.
BACKGROUND: After an injury to tissue such as the skin, hyperalgesia develops. Hyperalgesia is characterized by an increase in the magnitude of pain evoked by noxious stimuli. It has been... -
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- Effects of Ketamine on the Causalgiform Pain Produced by the Tight Ligation of L5, L6 Spinal Nerves in the Rat
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Lee WH, Han NH, kim TH
- KMID: 2104664
- J Korean Pain Soc.
- 1995 Apr;8(1):18-24.
We produced the causalgiform pain by the tight ligation of L5 and L6 spinal nerves in the adult rats. To evalute the effect of ketamine noncompetitive NMDA (N-methyl-D aspartate) antagoinst... -
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- Participation of IL-1β in temporomandibular nociception in rats with CFA-induced inflammation
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Ju JS, Choi SH, Kim HJ, Son JY, Ahn DK
- KMID: 2354200
- Int J Oral Biol.
- 2016 Sep;41(3):125-131.
- doi: 10.11620/IJOB.2016.41.3.125
The aim of the present study was to develop an animal model for evaluation of temporomandibular (TMJ) nociception under TMJ inflammation. We also investigated the participation of IL-1β in inflammation-induced... -
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- Peripheral Cellular Mechanisms of Artemin-induced Thermal Hyperalgesia in Rats
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Kim HJ, Yang KY, Lee MK, Park MK, Son JY, Ju JS, Ahn DK
- KMID: 2376780
- Int J Oral Biol.
- 2017 Mar;42(1):1-8.
- doi: 10.11620/IJOB.2017.42.1.1
In the present study, we investigated the role of peripheral ionotropic receptors in artemin-induced thermal hyperalgesia in the orofacial area. Male Sprague-Dawley rats weighting 230 to 280 g were used... -
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- Effect of oral pregabalin on opioid-induced hyperalgesia in patients undergoing laparo-endoscopic single-site urologic surgery
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Lee C, Lee HW, Kim JN
- KMID: 2236229
- Korean J Anesthesiol.
- 2013 Jan;64(1):19-24.
- doi: 10.4097/kjae.2013.64.1.19
BACKGROUND: Pregabalin is an antiepileptic drug that is effective for treating postoperative pain, neuropathic pain, anxiety, and hemodynamic instability. The aim of this study was to investigate the effect of... -
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- The Effect of Intrathecal NMDA and non-NMDA Receptor Antagonist on the Hyperalgesia Observed after Thermal Injury in the Rat
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Jun JH
- KMID: 2039879
- Korean J Anesthesiol.
- 1998 Apr;34(4):708-715.
- doi: 10.4097/kjae.1998.34.4.708
BACKGROUND: Previous reports have described NMDA antagonist reduced the nerve injury induced or inflammatory thermal hyperalgesia. This study evaluated the effects of spinally administered excitatory amino acid antagonists on the... -
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