- Hydroxyurea-induced Multiple Skin Ulcers
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Byun SY, Kwon SH, Bang S, Na JI
- KMID: 2388405
- Korean J Dermatol.
- 2013 Jun;51(6):480-481.
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- Chronic Hydroxyurea-induced Dermatomyositis-like Eruption Showing Epidermal Dysmaturation
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Park JH, Kim CD, Ryoo YW, Kim BC, Lee KS
- KMID: 2362382
- Ann Dermatol.
- 2002 Mar;14(1):28-30.
- doi: 10.5021/ad.2002.14.1.28
Hydroxyurea is an effective treatment for a variety of myeloproliferative disodrers. A distinct cutaneous reaction to long-term administration of hydroxyurea has been characterized and designated hydroxyurea dermopathy. Epidermal dysmaturation refers... -
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- A Case of Hydroxyurea-induced Melanonychia with Mucocutaneous Hyperpigmentation
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Kim SY, Jung HJ, Jung JW, Hahn HJ, Lee YW, Choe YB, Ahn KJ
- KMID: 1802089
- Korean J Dermatol.
- 2014 Apr;52(4):286-287.
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- A Case of Squamous Cell Carcinoma Associated With Hydroxyurea Therapy
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Yi JA, Lee WJ, Koo DW
- KMID: 2303075
- Korean J Dermatol.
- 2002 Nov;40(11):1440-1442.
The association of skin tumors and long-term use of hydroxyurea is recently recognized. We report a case of a patient who developed squamous cell carcinoma on the face during long-term... -
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- A Case of Hydroxyurea-induced Dermatomyositis-like Eruption
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Oh ST, Lee DW, Lee JY, Cho BK
- KMID: 2303194
- Korean J Dermatol.
- 2001 Jan;39(1):94-96.
Hydroxyurea is frequently used to treat myeloproliferative syndromes such as chronic myelogenous leukemia. Cutaneous lesions mimicking those seen in dermatomyositis have been rarely reported in the course of treatment with... -
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- Hydroxyurea-induced Longitudinal Melanonychia: A Case Report and Dermoscopic Findings
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Moon J, Park JS, Yang JH, Suh DH
- KMID: 2436717
- Korean J Dermatol.
- 2018 Jun;56(5):357-359.
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- A Hydroxyurea-induced Leg Ulcer
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Hwang SW, Hong SK, Kim SH, Seo JK, Lee D, Sung HS
- KMID: 2172063
- Ann Dermatol.
- 2009 Feb;21(1):39-41.
- doi: 10.5021/ad.2009.21.1.39
Hydroxyurea is a cytostatic agent that has recently become the drug of choice in the treatment of various myeloproliferative diseases. The cutaneous side effects of hydroxyurea include xerosis, hyperpigmentation, nail... -
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- Cerebral Infarction in Essential Thrombocythemia after Discontinuation of Hydroxyurea
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Kim JM, Cho EK, Han YS, Han JH, Kim DE
- KMID: 2338255
- J Korean Geriatr Soc.
- 2003 Jun;7(2):159-163.
Abnormalities in the number and function of platelets may contribute to thromboembolic complications in patients with essential thrombocythemia(ET). Physicians often use hydroxyurea which reduces the platelet count for the initial... -
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- A case of Hydroxyurea-induced fever
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Lee G, Kang HJ, Oh HA, Choi JH, Lee JL, Lee KH, Hyun MS, Ryu HM
- KMID: 1866923
- Korean J Med.
- 2002 May;62(5):581-583.
A patient with idiopathic hypereosinophilic syndrome is reported who developed a drug fever that may be related to the administration of hydroxyurea. Typically, this form of fever develops after a... -
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- A Case of Cutaneous Manifestations Associated With Hydroxyurea Therapy
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Jang SJ, Moon YJ, Choi YH, Kim JH, Won JY
- KMID: 2086696
- Korean J Dermatol.
- 2003 Jul;41(7):965-967.
Hydroxyurea is an antitumor agent that has attained an important role in the management of myeloproliferative syndromes. Its mechanism of action is not fully understood, but it appears to affect... -
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- Occurence of 17p Deletion with Blast Transformation in Idiopathic Myelofibrosis Treated with Hydroxyurea
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Ha JS, Ryoo NH, Kim JR, Jeon DS
- KMID: 1637298
- Korean J Hematol.
- 2004 Mar;39(1):46-50.
The recently described '17p deletion syndrome' is a clonal hematologic disease which has characteristic dysgranulopoietic features, such as pseudo-Pelger-Huet hypogranulation and small vacuoles in neutrophils and is strongly associated with... -
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- A Case of Hydroxyurea-Induced Cutaneous Ulceration and Squamous Cell Carcinoma
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Yun SJ, Lee JB, Kim SJ, Lee SC, Won YH
- KMID: 1604675
- Korean J Dermatol.
- 2002 Apr;40(4):433-436.
Hydroxyurea, one of conventional chemotherapies in chronic myelogenous leukemia(CML) and polycythemia vera, inhibits ribonucleotide reductase, which catalyzes the rate-limiting step in the de novo synthesis of deoxynucleotide triphosphates required for... -
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- A Case of Leukemic Transformation in Essential Thrombocythemia Treated with Hydroxyurea
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Lee JH, Kim TI, Kim GT, Lee YH, Jeong SD, Jang MH, Kim HK, Kim BC
- KMID: 2038499
- Korean J Hematol.
- 1997 Nov;32(3):433-439.
Essential thrombocythemia is a myeloproliferative disorder, characterized by marked thrombocytosis and marrow megakaryocytic hyperplasia. Although the major causes of morbidity and mortality are bleeding and thromboembolic events, the long-term prognosis... -
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- The Efficacy and Adverse Effect of Hydroxyurea as Compared with Anagrelide in Essential Thrombocythemia
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Seol YM, Kwon BR, Choi YJ, Lee KW, Shin HJ, Chung JS, Lee EY, Lee WS, Joo YD, Cho GJ
- KMID: 2252200
- Korean J Hematol.
- 2008 Jun;43(2):83-88.
- doi: 10.5045/kjh.2008.43.2.83
BACKGROUND: Although the platelet count may not always correlate with the risk of thrombosis, there is evidence that a strict control of the platelet count decreases the incidence of thrombotic... -
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- Hydroxyurea Therapy in Hemoglobin Madrid Patients
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Seo YK, Lee EH, Kim TW, Yang JH, Jung HL, Shim JY, Park MS, Keum DH
- KMID: 2252435
- Korean J Hematol.
- 2002 Feb;37(1):54-59.
Unstable hemoglobins (Hb) are variants of adult Hb that tend to precipitate and form insoluble inclusions (Heinz bodies) within red blood cells (RBC) and RBC precursors. More than 100 structurally... -
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- A Case of Idiopathic Hypereosinophihc Syndrome Assoclated with Pulmonary Infiltration
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Ryoo HM, Kweon YS, Chung JH, Lee KH, Lee HW, Kim DS, Lee SB
- KMID: 2352253
- Yeungnam Univ J Med.
- 1994 Dec;11(2):375-380.
- doi: 10.12701/yujm.1994.11.2.375
The idiopathic hypereosinophilic syndrome consists of peripheral blood eosinophilia of 1500/mm3 or more without a known cause, plus signs and symptoms of organ eosinophilia. The prognosis of HES without treatment is... -
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- A Case of Amyopathic Dermatomyositis
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Moon DG, Lee CW
- KMID: 2086456
- Korean J Dermatol.
- 2001 Jul;39(7):827-828.
Amyopathic dermatomyositis is diagnosed when the biopsy-confirmed cutaneous lesions of dermatomyositis are present for longer than 2 years in the absence of muscle weakness, elevated muscle enzymes, and the history... -
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- A Case of Childhood Essential Thrombocythemia
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Lee JE, Lee YJ, Huh JH, Lee KS
- KMID: 2072486
- Korean J Pediatr Hematol Oncol.
- 1999 Apr;6(1):141-145.
Essential thrombocythemia in childhood is a rare clonal myeloproliferative disorder in the multipotent stem cell origin and is associated with an increased risk of thrombohemorrhagic complications. The one of... -
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- Clinical management of suspected intracranial meningioma in three dogs with pulsed high-dose hydroxyurea
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Cho JG, Song KH, Seo KW
- KMID: 2414720
- Korean J Vet Res.
- 2018 Jun;58(2):103-106.
- doi: 10.14405/kjvr.2018.58.2.103
Three aged dogs, all over 15 years old, with multiple seizure events and various neurologic signs such as head turn and ataxia were brought to the referring hospital. Two cases... -
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- Hydroxyurea with Radiation Therapy of the Carcinoma of the Cervix IIA, IIB
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Kim JH, Youn SM, Kim OB
- KMID: 2097521
- J Korean Soc Ther Radiol.
- 1995 Dec;13(4):369-376.
PURPOSE: To evaluate the efficacy of hydroxyurea with radiation in carcinoma of the cervix, huge exophytic or endophytic stage IIa and Iib. MATERIALS AND METHODS: Sixty four patients with carcinoma of... -
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