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Mucosal Vaccine Delivery Using Mucoadhesive Polymer Particulate Systems

Cho CS, Hwang SK, Gu MJ, Kim CG, Kim SK, Ju DB, Yun CH, Kim HJ

Vaccination has been recently attracted as one of the most successful medical treatments of the prevalence of many infectious diseases. Mucosal vaccination has been interested in many researchers because mucosal...
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Congenital Myasthenic Syndrome Related to CHRNA1 Variant

Ahn JW, Hwang SK, Kim JH, Jung H, Park JS

Congenital myasthenic syndromes are a genetically and clinically heterogeneous group of neuromuscular disorders linked by abnormal signal transmission at the motor endplate caused by various genetic defects. Major clinical symptoms...
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Fentanyl versus Remifentanil for Cough Suppression and Recovery after Video-Assisted Thoracic Surgery

Son HW, Lee JM, Park SH, Lee YJ, Oh JM, Hwang SK

Background: Various methods have been used to reduce postoperative pain after thoracic surgery. However, these methods may affect the patient’s respiratory response and delay recovery from anesthesia. We aimed to...
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A new type of oculocutaneous albinism with a novel OCA2 mutation

Lee SY, Lee EJ, Byun JC, Jang KM, Kim SY, Hwang SK

Oculocutaneous albinism (OCA) is a group of rare genetically heterogeneous disorders, characterized by hypopigmentation of the eyes, skin, and hair, which result in ocular abnormalities and a risk of developing...
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The Effect of White Noise on Sleep in Hospitalized Patients: A Randomized Controlled Trial

Cho ME, Hwang SK

Purpose: During hospitalization, sleep can be disturbed and the quality reduced. This study investigated the effect of applying white noise on hospitalized patients for improving their sleep quality. Methods: In...
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Retinal Microvascular Abnormalities in Patients with Type I Neurofibromatosis

Choi HJ, Yoon JH, Son BJ, Hwang SK, Chun BY

Purpose: To evaluate the findings and frequencies of retinal microvascular abnormalities observed in patients with type 1 neurofibromatosis. Methods: Fundus photographs of 61 patients with type 1 neurofibromatosis and 61 controls...
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Clinical Characteristics of Epilepsy and Its Risk Factors in Neurofibromatosis Type 1: A Single-Center Study

Shin A, Byun JC, Hwang SK, Kwon S, Lee YJ

Purpose: This study investigated the clinical characteristics and risk factors of epilepsy in patients with neurofibromatosis type 1 (NF1) at a tertiary center. Methods: The medical records of 103 children...
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KCNQ2 Encephalopathy Showing a Distinct Ictal Amplitude-Integrated Electroencephalographic Pattern

Kwak N, Lee YJ, Kim D, Hwang SK, Kwon S, Lee EJ

KCNQ2 mutations induce a neonatal-onset epileptic encephalopathy of widely varying severity, ranging from benign familial neonatal epilepsy to severe refractory epileptic encephalopathy. Refractory seizures with KCNQ2 mutations have a positive...
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Acute Type A Aortic Dissection in a Patient with Situs Inversus Totalis

Kim DK, Lee JM, Heo SY, Jung JP, Park CR, Lee YJ, Lee SC, Hwang SK, Kim GS

We describe the occurrence of acute type A aortic dissection in a patient with situs inversus totalis. A 37-year-old man presented to the emergency department with acute chest pain. Initial...
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A Case of Temporal Bone Cholesterol Granuloma Extending to Posterior Cranial Fossa without Middle Ear Involvement

Ko MC, Jeong JY, Hwang SK, Yoo MH

Cholesterol granulomas of the temporal bone can occur in the petrous apex, middle ear, and mastoid cavity. Although cholesterol granulomas in the petrous apex often extend to the middle cranial...
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The molecular pathophysiology of vascular anomalies: Genomic research

Kim JS, Hwang SK, Chung HY

Vascular anomalies are congenital localized abnormalities that result from improper development and maintenance of the vasculature. The lesions of vascular anomalies vary in location, type, and clinical severity of the...
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Gamma Knife Radiosurgery Using Co-Registration with PET-CT and MRI for Recurrent Nasopharyngeal Carcinoma with Previous Radiotherapy : A Single Center 14-Year Experience

Lee C, Park SH, Yoon SY, Park KS, Hwang JH, Hwang SK

Objective : We retrospectively evaluated the efficacy of Gamma Knife radiosurgery (GKS) for recurrent nasopharyngeal carcinoma (NPC) in patients who previously underwent radiotherapy, and analyzed the treatment outcomes over 14...
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Clinical Spectrum of Posterior Reversible Encephalopathy Syndrome in Children

Hwang SK, Lee YJ, Lee SM, Kwon S

Posterior reversible encephalopathy syndrome (PRES) is a complex neurological condition characterized by the acute onset of neurological symptoms, such as seizures and potentially reversible vasogenic edema with preferential involvement of...
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Combined treatment of surgery and sclerotherapyfor sinus pericranii

Ryu JY, Lee JH, Lee JS, Lee JW, Lee SJ, Lee JM, Lee SY, Huh S, Kim JY, Hwang SK, Chung HY

Sinus pericranii is a rare vascular anomaly characterized by abnormal venous communication between the inner and outer regions of the cranial cavity. Here, we report a case of sinus pericranii and venous...
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Variation in clinical usefulness of biomarkers of acute kidney injury in young children undergoing cardiac surgery

Baek HS, Lee Y, Jang HM, Cho J, Hyun MC, Kim YH, Hwang SK, Cho MH

Background: Acute kidney injury (AKI) is one of the most significant postoperative complications of pediatric cardiac surgery. Because serum creatinine has limitations as a diagnostic marker of AKI, new biomarkers...
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Real-Life Effectiveness and Tolerability of Perampanel in Pediatric Patients Aged 4 Years or Older with Epilepsy: A Korean National Multicenter Study

Hwang SK, Lee YJ, Nam SO, Kim WS, Kim JS, Kim SJ, Lee YJ, Kwon S

BACKGROUND AND PURPOSE: The US Food and Drug Administration approval for perampanel has only recently been expanded to patients as young as 4 years, and so there have been few...
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Propionic Acidemia with Novel Mutation Presenting as Recurrent Pancreatitis in a Child

Choe JY, Jang KM, Min SY, Hwang SK, Kang B, Choe BH

Propionic acidemia (PA) is a rare organic acidemia resulting from a deficiency of the mitochondrial enzyme propionyl-coenzyme A carboxylase. Most cases are diagnosed after the detection of metabolic abnormalities—such as...
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Spatial Learning and Motor Deficits in Vacuolar Protein Sorting-associated Protein 13b (Vps13b) Mutant Mouse

Kim MJ, Lee RU, Oh J, Choi JE, Kim H, Lee K, Hwang SK, Lee JH, Lee JA, Kaang BK, Lim CS, Lee YS

Vacuolar protein sorting-associated protein 13B (VPS13B), also known as COH1, is one of the VPS13 family members which is involved in transmembrane transport, Golgi integrity, and neuritogenesis. Mutations in the...
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Stereotactic Radiosurgery for Dural Arteriovenous Fistulas Involving the Transverse-Sigmoid Sinus: A Single Center Experience and Review of the Literatures

Baek HG, Park SH, Park KS, Kang DH, Hwang JH, Hwang SK

OBJECTIVE: We retrospectively assessed the efficacy of stereotactic radiosurgery (SRS) for dural arteriovenous fistulas (DAVFs) involving the transverse-sigmoid sinus and analyzed the angiographic and clinical results with our 8-year experience. METHODS:...
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Predictive Validity of Pressure Ulcer Risk Assessment Scales among Patients in a Trauma Intensive Care Unit

Choi JE, Hwang SK

PURPOSE: The aims of this study were to identify the incidence of pressure ulcers and to compare the predictive validities of pressure ulcer risk assessment scales among trauma patients. METHODS: This...
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