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Hydrogen sulfide ameliorates abdominal aorta coarctationinduced myocardial fibrosis by inhibiting pyroptosis through regulating eukaryotic translation initiation factor 2αα phosphorylation and activating PI3K/AKT1 pathway

Li Y, Wu Z, Hu J, Liu G, Hu H, Ouyang F, Yang J

This study aimed to assess the effects of exogenous hydrogen sulfide (H2S) on abdominal aorta coarctation (AAC) induced myocardial fibrosis (MF) and autophagy in rats. Forty-four Sprague–Dawley rats were randomly...
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Tracheal Membrane Rupture as the Cause of Pneumomediastinum in a Patient with COVID-19

Fu B, Hu J, Chen T, Fu X

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PIK3R3 regulates PPARα expression to stimulate fatty acid β-oxidation and decrease hepatosteatosis

Yang X, Fu Y, Hu F, Luo X, Hu J, Wang G

Phosphatidylinositol 3-kinase (PI3K) signaling plays an important role in the regulation of cellular lipid metabolism and non-alcoholic fatty liver disease (NAFLD). However, little is known about the role of the...
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MicroRNA-186 targets SKP2 to induce p27(Kip1)-mediated pituitary tumor cell cycle deregulation and modulate cell proliferation

He Z, Chen L, Wang Q, Yin C, Hu J, Hu X, Fei F, Tang J

Pituitary tumors are usually benign but can occasionally exhibit hormonal and proliferative behaviors. Dysregulation of the G1/S restriction point largely contributes to the over-proliferation of pituitary tumor cells. F-box protein...
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Colonic Hypersensitivity and Sensitization of Voltage-gated Sodium Channels in Primary Sensory Neurons in Rats with Diabetes

Hu J, Song ZY, Zhang HH, Qin X, Hu S, Jiang X, Xu GY

  • KMID: 2379712
  • J Neurogastroenterol Motil.
  • 2016 Jan;22(1):129-140.
  • doi: 10.5056/jnm15091
BACKGROUND/AIMS: Patients with long-standing diabetes often demonstrate intestinal dysfunction and abdominal pain. However, the pathophysiology of abdominal pain in diabetic patients remains elusive. The purpose of study was to determine...
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Macrophage and Adipocyte Mitochondrial Dysfunction in Obesity-Induced Metabolic Diseases

Wang L, Hu J, Zhou H

Obesity is one of major health burdens of modern society as it contributes to the growing prevalence of its related comorbidities, such as diabetes, cardiovascular diseases, and some cancers. A...
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A Case of Tuberculous Otitis Media Combined with Cholesteatoma

Kim JH, Hu J, Kim MY, Kim HJ

  • KMID: 2141455
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 Oct;40(10):1487-1490.
As tuberculous otitis media is nowadays not common, young physicians are not good at the disease. Accordingly, the correct diagnosis can be delayed causing complications, for instances, irreversible hearing loss,...
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The Clinical Manifestation of p.Asp50Asn Heterozygous Mutation of GJB2 Gene in 3 Members of a Family Is Similar to That of Clouston Syndrome

Xu Y, Wang M, Huang L, Hu J

Keratitis-ichthyosis-deafness (KID) syndrome has genetic heterogeneity, and the clinical manifestations of some patients may overlap with Clouston syndrome. A 34-year-old female patient came to our department with a complain of...
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Right-to-Left Displacement of an Airgun Lead Bullet after Transorbital Entry into the Skull Complicated by Posttraumatic Epilepsy : A Case Report

Wang Cb, Wang H, Zhao Js, Wu Zj, Liu Hd, Wang Cj, Li Ar, Wang D, Hu J

Penetrating head injury is a serious open cranial injury. In civilians, it is often caused by non-missile, low velocity flying objects that penetrate the skull through a weak cranial structure,...
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Continuity of Care in Chronic Diseases: A Concept Analysis by Literature Review

Hu J, Wang Y, Li X

Purpose: This study aimed to utilize concept analysis to obtain a better understanding of the concept of “continuity of care” in chronic diseases. Methods: The concept of continuity of care...
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Valproic Acid Enhance Reprogramming of Bactrian Camel Cells through Promoting the Expression of Endogenous Gene c-Myc and the Process of Angiogenesis

Li Z, Ge W, Li Y, Zhang Y, Zhao X, Hu J

Background and Objectives: Induced pluripotent stem cells (iPSCs) are usually generated by reprogramming differentiated cells through the introduction of specific transcription factors, but this is a difficult and inefficient process. Valproic...
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HPV-Related Retroperitoneal Squamous Cell Carcinoma of Unknown Primary: A Case Report

Oh HJ, Park EH, Lee YB, Hu J, Lee GJ, Chun SH, Lee MY, Lee DW, Kim J, Jin JY

A 56-year-old female was referred to our hospital due to a mass measuring 5 cm in size in the left pelvic cavity, which was found incidentally during a health examination...
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The Development of Clinical Document Standards for Semantic Interoperability in China

Yang P, Pan F, Liu D, Xu Y, Wan Y, Tu H, Tang X, Hu J

OBJECTIVES: This study is aimed at developing a set of data groups (DGs) to be employed as reusable building blocks for the construction of the eight most common clinical documents...
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The Association Between Fasting C-peptide and Gastrointestinal Symptoms of Gastroparesis in Type 2 Diabetic Patients

Huang Y, Zhang H, Zhang M, Li W, Wang J, Hu J

  • KMID: 2433526
  • J Neurogastroenterol Motil.
  • 2017 Apr;23(2):254-261.
  • doi: 10.5056/jnm16091
BACKGROUND/AIMS: The relationship between C-peptide levels and gastrointestinal (GI) symptoms in type 2 diabetic patients is not clear. The purpose of this study is to examine the association between fasting...
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Increased Progastrin-Releasing Peptide Expression is Associated with Progression in Gastric Cancer Patients

Li L, Yin X, Meng H, Hu J, Yu Z, Xu J

PURPOSE: The purpose of this study was to assess the diagnostic and prognostic value of serum progastrin-releasing peptide (ProGRP) in patients with gastric cancer (GC). MATERIALS AND METHODS: A total of...
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Study of the Shoulder Function after Neck Dissection

Kim SH, Kim JH, Hu J, Rho YS, Lim HJ, Park DS

  • KMID: 1559640
  • Korean J Otolaryngol-Head Neck Surg.
  • 1998 May;41(5):647-652.
BACKGROUND AND OBJECTIVES: Radical neck dissection (RND) has been a standard treatment for the head and neck cancer with metastasis to the cervical lymphatics. The sacrifice of the spinal accessory...
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In vivo Effect of Systemic pam-idronate Disodium on bo_ne Resorption in Experimental Cholesteatoma

Kim HJ, Kim JH, Hu J, Yoon TH, Jun BH

  • KMID: 2274469
  • Korean J Otolaryngol-Head Neck Surg.
  • 1998 Sep;41(9):1111-1117.
BACKGROUND AND OBJECTIVES: Bone resorption of adjacent structures in aural cholesteatoma is mostly responsible for serious complication of the disease. Recent researches have been aimed at preventing bone resorption with...
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Complete genome and phylogenetic analysis of bovine papillomavirus type 15 in Southern Xinjiang dairy cow

Hu J, Zhang W, Chauhan SS, Shi C, Song Y, Zhao Y, Wang Z, Cheng L, Zhang Y

Background: Bovine papilloma is a neoplastic disease caused by bovine papillomaviruses (BPVs), which were recently divided into 5 genera and at least 24 genotypes. Objectives: The complete genome sequence of BPV...
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BRAF-Activated Long Noncoding RNA Modulates Papillary Thyroid Carcinoma Cell Proliferation through Regulating Thyroid Stimulating Hormone Receptor

Zheng H, Wang M, Jiang L, Chu H, Hu J, Ning J, Li B, Wang D, Xu J

PURPOSE: The importance of long noncoding RNAs (lncRNAs) in tumorigenesis has recently been demonstrated. However, the role of lncRNAs in development of thyroid cancer remains largely unknown. MATERIALS AND METHODS: Using...
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Efficacy and Safety of Pulse Magnetic Therapy System in Insomnia Disorder: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

Liao J, Wang S, Zhou B, Liang W, Ma P, Lin M, Lin W, Li C, Zhang X, Li H, Cui Y, Hu J, Qin Y, Deng Y, Fu A, Zhu T, Zhang S, Qu Y, Xing L, Li W, Feng F, Yao X, Zhang G, Pan J

Objective This study’s objective is to assess the efficacy and safety of Pulsed Magnetic Therapy System (PMTS) in improving insomnia disorder. Methods Participants with insomnia disorder were randomly assigned to receive...
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