- A Schematic Overview of the Current Status of Male Infertility Practice
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Agarwal A, Majzoub A, Parekh N, Henkel R
- KMID: 2502999
- World J Mens Health.
- 2020 Jul;38(3):308-322.
- doi: 10.5534/wjmh.190068
The practice of male infertility has dramatically evolved over the past few decades. This has been achieved after the realization of the important contribution the male counterpart holds in the... -
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- Editorial Commentary on Draft of World Health Organization Sixth Edition Laboratory Manual for the Examination and Processing of Human Semen
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Kandil H, Agarwal A, Saleh R, Boitrelle F, Arafa M, Vogiatzi P, Henkel R, Zini A, Shah R
- KMID: 2519900
- World J Mens Health.
- 2021 Oct;39(4):577-580.
- doi: 10.5534/wjmh.210074
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- Microtubular Dysfunction and Male Infertility
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Gunes S, Sengupta P, Henkel R, Alguraigari A, Sinigaglia MM, Kayal M, Joumah A, Agarwal A
- KMID: 2465406
- World J Mens Health.
- 2020 Jan;38(1):9-23.
- doi: 10.5534/wjmh.180066
Microtubules are the prime component of the cytoskeleton along with microfilaments. Being vital for organelle transport and cellular divisions during spermatogenesis and sperm motility process, microtubules ascertain functional capacity of... -
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- A Novel Approach to Improving the Reliability of Manual Semen Analysis: A Paradigm Shift in the Workup of Infertile Men
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Douglas C, Parekh N, Kahn LG, Henkel R, Agarwal A
- KMID: 2513969
- World J Mens Health.
- 2021 Apr;39(2):172-185.
- doi: 10.5534/wjmh.190088
Conventional semen analysis (SA) is an essential component of the male infertility workup, but requires laboratories to rigorously train and monitor technicians as well as regularly perform quality assurance assessments.... -
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- An In-Depth Bibliometric Analysis and Current Perspective on Male infertility Research
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Baskaran S, Agarwal A, Leisegang K, Pushparaj PN, Selvam MKP, Henkel R
- KMID: 2513976
- World J Mens Health.
- 2021 Apr;39(2):302-314.
- doi: 10.5534/wjmh.180114
Purpose: Male infertility is emerging as a major, escalating global health problem that imposes the need to investigate research trends in male infertility. The purpose of this study is to... -
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- Protective effects of saffron against zearalenone-induced alterations in reproductive hormones in female mice (Mus musculus)
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Ahmad B, Shrivastava VK, Saleh R, Henkel R, Agarwal A
- KMID: 2427411
- Clin Exp Reprod Med.
- 2018 Dec;45(4):163-169.
- doi: 10.5653/cerm.2018.45.4.163
OBJECTIVE: Zearalenone (ZEA) is a mycotoxin with potent estrogenic effects. Saffron is an herbal product that has antioxidant activities. The objective of this study was to investigate the protective role... -
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- Ritalinic Acid Stimulates Human Sperm Motility and Maintains Vitality In Vitro
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Harlev A, Henkel R, Samanta L, Agarwal A
- KMID: 2465410
- World J Mens Health.
- 2020 Jan;38(1):61-67.
- doi: 10.5534/wjmh.180127
PURPOSE: To evaluate the in vitro impact of ritalinic acid (RA), a major metabolite of methylphenidate (drug to treat attention-deficit hyperactivity disorder), on sperm motility, vitality and oxidative stress. MATERIALS AND... -
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- Standardized Laboratory Procedures, Quality Control and Quality Assurance Are Key Requirements for Accurate Semen Analysis in the Evaluation of Infertile Male
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Agarwal A, Sharma R, Gupta S, Finelli R, Parekh N, Selvam MKP, Pompeu CP, Madani S, Belo A, Darbandi M, Singh N, Darbandi S, Covarrubias S, Sadeghi R, Arafa M, Majzoub A, Caraballo M, Giroski A, McNulty K, Durairajanayagam D, Henkel R
- KMID: 2523636
- World J Mens Health.
- 2022 Jan;40(1):52-65.
- doi: 10.5534/wjmh.210022
Semen analysis is a basic test for evaluating male fertility potential, as it plays an essential role in driving the future management and treatment of infertility in couples. Manual semen... -
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- Role of Cytocentrifugation Combined with Nuclear Fast Picroindigocarmine Staining in Detecting Cryptozoospermia in Men Diagnosed with Azoospermia
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Sharma RK, Gupta S, Agarwal A, Finelli R, Kuroda S, Saleh R, Boitrelle F, Kavoussi P, Gül M, Tadros N, Ko E, Farkouh A, Henkel R, Arafa M, Rambhatla A, Shah R
- KMID: 2537111
- World J Mens Health.
- 2022 Oct;40(4):627-635.
- doi: 10.5534/wjmh.210210
Purpose: Azoospermia is defined as the absence of spermatozoa in the pellet of a centrifuged semen sample. In fact, when a basic semen analysis fails to detect sperm in the... -
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- Male Fertility and the COVID-19 Pandemic: Systematic Review of the Literature
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Khalili MA, Leisegang K, Majzoub A, Finelli R, Panner Selvam MK, Henkel R, Mojgan M, Agarwal A
- KMID: 2506416
- World J Mens Health.
- 2020 Oct;38(4):506-520.
- doi: 10.5534/wjmh.200134
Purpose: Since its discovery in December 2019, the novel coronavirus SARS-CoV-2 has spread globally, causing the current COVID-19 (coronavirus disease-19) pandemic. As there is an increase of infections in the... -
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- Highly Cited Articles in the Field of Male Infertility and Antioxidants: A Scientometric Analysis
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Agarwal A, Selvam MKP, Baskaran S, Finelli R, Leisegang K, Barbăroșie C, Pushparaj PN, Robert KA, Ambar RF, Iovine C, Durairajanayagam D, Henkel R
- KMID: 2519917
- World J Mens Health.
- 2021 Oct;39(4):760-775.
- doi: 10.5534/wjmh.200181
Purpose: The objective of this scientometric analysis was to recognize the top 100 cited articles on ‘Male infertility and Antioxidants’ and analyze its publication characteristics. Materials and Methods: The Scopus database... -
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- Utility of Antioxidants in the Treatment of Male Infertility: Clinical Guidelines Based on a Systematic Review and Analysis of Evidence
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Agarwal A, Leisegang K, Majzoub A, Henkel R, Finelli R, Panner Selvam MK, Tadros N, Parekh N, Ko EY, Cho CL, Arafa M, Alves MG, Oliveira PF, Alvarez JG, Shah R
- KMID: 2513974
- World J Mens Health.
- 2021 Apr;39(2):233-290.
- doi: 10.5534/wjmh.200196
It is widely accepted that oxidative stress plays an important role in the pathophysiology of male infertility and that antioxidants could have a significant role in the treatment of male... -
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- Sperm DNA Fragmentation: A New Guideline for Clinicians
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Agarwal A, Majzoub A, Baskaran S, Panner Selvam MK, Cho CL, Henkel R, Finelli R, Leisegang K, Sengupta P, Barbarosie C, Parekh N, Alves MG, Ko E, Arafa M, Tadros N, Ramasamy R, Kavoussi P, Ambar R, Kuchakulla M, Robert KA, Iovine C, Durairajanayagam D, Jindal S, Shah R
- KMID: 2506412
- World J Mens Health.
- 2020 Oct;38(4):412-471.
- doi: 10.5534/wjmh.200128
Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases of spermatogenesis, which imparts compaction and... -
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- Consensus and Diversity in the Management of Varicocele for Male Infertility: Results of a Global Practice Survey and Comparison with Guidelines and Recommendations
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Shah R, Agarwal A, Kavoussi P, Rambhatla A, Saleh R, Cannarella R, Harraz AM, Boitrelle F, Kuroda S, Hamoda TAAAM, Zini A, Ko E, Calik G, Toprak T, Kandil H, Gül M, Bakırcıoğlu ME, Parekh N, Russo GI, Tadros N, Kadioglu A, Arafa M, Chung E, Rajmil O, Dimitriadis F, Malhotra V, Salvio G, Henkel R, Le TV, Sogutdelen E, Vij S, Alarbid A, Gudeloglu A, Tsujimura A, Calogero AE, Meliegy AE, Crafa A, Kalkanli A, Baser A, Hazir B, Giulioni C, Cho CL, Ho CC, Salzano C, Zylbersztejn DS, Tien DMB, Pescatori E, Borges E, Serefoglu EC, Saïs-Hamza E, Huyghe E, Ceyhan E, Caroppo E, Castiglioni F, Bahar F, Gokalp F, Lombardo F, Gadda F, Duarsa GWK, Pinggera GM, Busetto GM, Balercia G, Cito G, Blecher G, Franco G, Liguori G, Elbardisi H, Keskin H, Lin H, Taniguchi H, Park HJ, Ziouziou I, Rosette Jdl, Hotaling J, Ramsay J, Molina JMC, Lo KL, Bocu K, Khalafalla K, Bowa K, Okada K, Nagao K, Chiba K, Hakim L, Makarounis K, Hehemann M, Peña MR, Falcone M, Bendayan M, Martinez M, Timpano M
- KMID: 2537128
- World J Mens Health.
- 2023 Jan;41(1):164-197.
- doi: 10.5534/wjmh.220048
Purpose: Varicocele is a common problem among infertile men. Varicocele repair (VR) is frequently performed to improve semen parameters and the chances of pregnancy. However, there is a lack of... -
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- A Web-Based Global Educational Model for Training in Semen Analysis during the COVID-19 Pandemic
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Agarwal A, Finelli R, Durairajanayagam D, Leisegang K, Sharma R, Gupta S, Singh N, Belo A, Darbandi M, Madani S, Covarrubias S, Darbandi S, Sadeghi R, Pompeu C, Boitrelle F, Kandil H, Saleh R, Arafa M, Vogiatzi P, Rosas IM, Anagnostopoulou C, Chockalingam A, Wirka KA, Sallam HN, Shah R, Henkel R
- KMID: 2519920
- World J Mens Health.
- 2021 Oct;39(4):804-817.
- doi: 10.5534/wjmh.210075
Purpose: In response to the COVID-19 pandemic, the American Center for Reproductive Medicine (ACRM) transitioned its annual training in assisted reproductive technology (ART) from a hands-on, laboratory-based training course to... -
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- Sperm Morphology Assessment in the Era of Intracytoplasmic Sperm Injection: Reliable Results Require Focus on Standardization, Quality Control, and Training
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Agarwal A, Sharma R, Gupta S, Finelli R, Parekh N, Selvam MKP, Henkel R, Durairajanayagam D, Pompeu C, Madani S, Belo A, Singh N, Covarrubias S, Darbandi S, Sadeghi R, Darbandi M, Vogiatzi P, Boitrelle F, Simopoulou M, Saleh R, Arafa M, Majzoub A, Kandil H, Zini A, Ko E, Alvarez JG, Martinez M, Ramsay J, Jindal S, Busetto GM, Sallam H, Maldonado I, Anagnostopoulou C, Alves MG, Sengupta P, Gilany K, Evenson DP, Lewis SE, Gosalvez J, Ambar RF, Shah R
- KMID: 2530704
- World J Mens Health.
- 2022 Jul;40(3):347-360.
- doi: 10.5534/wjmh.210054
Semen analysis is the first, and frequently, the only step in the evaluation of male fertility. Although the laboratory procedures are conducted according to the World Health Organization (WHO) guidelines,... -
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- Comprehensive Analysis of Global Research on Human Varicocele: A Scientometric Approach
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Agarwal A, Finelli R, Durairajanayagam D, Leisegang K, Henkel R, Salvio G, Aghamajidi A, Sengupta P, Crisóstomo L, Tsioulou PA, Roychoudhury S, Finocchi F, Darbandi M, Mottola F, Darbandi S, Iovine C, Santonastaso M, Zaker H, Kesari KK, Nomanzadeh A, Gugnani N, Rambhatla A, Duran MB, Ceyhan E, Kandil H, Arafa M, Saleh R, Shah R, Ko E, Boitrelle F
- KMID: 2537112
- World J Mens Health.
- 2022 Oct;40(4):636-652.
- doi: 10.5534/wjmh.210202
Purpose: This study provides a comprehensive analysis of research trends on the etiology, mechanisms, potential risk factors, diagnosis, prognosis, surgical and non-surgical treatment of varicocele, and clinical outcomes before and... -
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- Relevance of Leukocytospermia and Semen Culture and Its True Place in Diagnosing and Treating Male Infertility
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Sharma R, Gupta S, Agarwal A, Henkel R, Finelli R, Parekh N, Saleh R, Arafa M, Ko E, Zini A, Tadros N, Shah R, Ambar RF, Elbardisi H, Sengupta P, Martinez M, Boitrelle F, Simopoulou M, Vogiatzi P, Gosalvez J, Kavoussi P, Kandil H, Palani A, Peña MR, Rajmil O, Busetto GM, Anagnostopoulou C, Micic S, Alves MG, Rocco L, Mostafa T, Alvarez JG, Jindal S, Sallam HN, Rosas IM, Lewis SE, AlSaid S, Altan M, Park HJ, Ramsay J, Parekattil S, Sabbaghian M, Tremellen K, Khalafalla K, Durairajanayagam D, Colpi GM
- KMID: 2527318
- World J Mens Health.
- 2022 Apr;40(2):191-207.
- doi: 10.5534/wjmh.210063
The current WHO 2010 manual for human semen analysis defines leukocytospermia as the presence of peroxidase-positive leukocytes at a concentration >1×10 6 /mL of semen. Granular leukocytes when activated are... -
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- Sperm Vitality and Necrozoospermia: Diagnosis, Management, and Results of a Global Survey of Clinical Practice
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Agarwal A, Sharma RK, Gupta S, Boitrelle F, Finelli R, Parekh N, Durairajanayagam D, Saleh R, Arafa M, Cho CL, Farkouh A, Rambhatla A, Henkel R, Vogiatzi P, Tadros N, Kavoussi P, Ko E, Leisegang K, Kandil H, Palani A, Salvio G, Mostafa T, Rajmil O, Banihani SA, Schon S, Le TV, Birowo P, Çeker G, Alvarez J, Corral Molina JM, Ho CC, Calogero AE, Khalafalla K, Duran MB, Kuroda S, Colpi GM, Zini A, Anagnostopoulou C, Pescatori E, Chung E, Caroppo E, Dimitriadis F, Pinggera GM, Busetto GM, Balercia G, Elbardisi H, Taniguchi H, Park HJ, Rosas IM, Rosette Jdl, Ramsay J, Bowa K, Simopoulou M, Rodriguez MG, Sabbaghian M, Martinez M, Sadighi Gilani MA, Al-Marhoon MS, Kosgi R, Cannarella R, Micic S, Fukuhara S, Parekattil S, Jindal S, Abdel-Meguid TAA, Morimoto Y, Shah R
- KMID: 2527321
- World J Mens Health.
- 2022 Apr;40(2):228-242.
- doi: 10.5534/wjmh.210149
Sperm vitality testing is a basic semen examination that has been described in the World Health Organization (WHO) Laboratory Manual for the Examination and Processing of Human Semen from its... -
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- Antisperm Antibody Testing: A Comprehensive Review of Its Role in the Management of Immunological Male Infertility and Results of a Global Survey of Clinical Practices
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Gupta S, Sharma R, Agarwal A, Boitrelle F, Finelli R, Farkouh A, Saleh R, Abdel-Meguid TAA, Gül M, Zilaitiene B, Ko E, Rambhatla A, Zini A, Leisegang K, Kuroda S, Henkel R, Cannarella R, Palani A, Cho CL, Ho CC, Zylbersztejn DS, Pescatori E, Chung E, Dimitriadis F, Pinggera GM, Busetto GM, Balercia G, Salvio G, Colpi GM, Çeker G, Taniguchi H, Kandil H, Park HJ, Rosas IM, Rosette Jdl, Cardoso JPG, Ramsay J, Alvarez J, Corral Molina JM, Khalafalla K, Bowa K, Tremellen K, Evgeni E, Rocco L, Rodriguez Peña MG, Sabbaghian M, Martinez M, Arafa M, Al-Marhoon MS, Tadros N, Garrido N, Rajmil O, Sengupta P, Vogiatzi P, Kavoussi P, Birowo P, Kosgi R, Bani-Hani S, Micic S, Parekattil S, Jindal S, Le TV, Mostafa T, Toprak T, Morimoto Y, Malhotra V, Aghamajidi A, Durairajanayagam D, Shah R
- KMID: 2530707
- World J Mens Health.
- 2022 Jul;40(3):380-398.
- doi: 10.5534/wjmh.210164
Antisperm antibodies (ASA), as a cause of male infertility, have been detected in infertile males as early as 1954. Multiple causes of ASA production have been identified, and they are... -
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