- A Novel Heterozygous Missense Variant (c.667G>T;p.Gly223Cys) in USH1C That Interferes With Cadherin-Related 23 and Harmonin Interaction Causes Autosomal Dominant Nonsyndromic Hearing Loss
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Song JS, Bahloul A, Petit C, Kim SJ, Moon IJ, Lee J, Ki CS
- KMID: 2466015
- Ann Lab Med.
- 2020 May;40(3):224-231.
- doi: 10.3343/alm.2020.40.3.224
BACKGROUND: Pathogenic variants of USH1C, encoding a PDZ-domain-containing protein called harmonin, have been known to cause autosomal recessive syndromic or nonsyndromic hearing loss (NSHL). We identified a causative gene in... -
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- Safety and efficacy of transcutaneous bone conduction implant surgery for hearing improvement in microtia patients with bilateral hearing impairment
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Cheon JH, Lee HC, Im GJ, Park JY, Park C
- KMID: 2465552
- Arch Plast Surg.
- 2019 Nov;46(6):525-534.
- doi: 10.5999/aps.2019.00661
BACKGROUND: In microtia patients with bilateral hearing impairment, hearing improvement is crucial for language development and performance. External auditory canal reconstruction (EACR) has been performed to improve hearing, but often... -
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- Genetics of Hearing Loss in North Iran Population: An Update of Spectrum and Frequency of GJB2 Mutations
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Koohiyan M, Azadegan-Dehkordi F, Koohian F, Hashemzadeh-Chaleshtori M
- KMID: 2460017
- J Audiol Otol.
- 2019 Oct;23(4):175-180.
- doi: 10.7874/jao.2019.00059
Diagnosis of pre-lingual hearing loss (HL) is difficult owing to the high number of genes responsible. The most frequent cause of HL is DFNB1 due to mutations in the GJB2... -
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- Asymptomatic Hearing Impairment Frequently Occurs in Early-Onset Parkinson's Disease
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Shetty K, Krishnan S, Thulaseedharan JV, Mohan M, Kishore A
- KMID: 2449679
- J Mov Disord.
- 2019 May;12(2):84-90.
- doi: 10.14802/jmd.18048
OBJECTIVE: Recent reports of hearing impairment in Parkinson's disease (PD) have suggested that auditory dysfunction could be a non-motor manifestation of PD. These reports were based on observations of elderly... -
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- Association between cadmium exposure and hearing impairment: a population-based study in Korean adults
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Jung DJ
- KMID: 2449327
- Yeungnam Univ J Med.
- 2019 May;36(2):141-147.
- doi: 10.12701/yujm.2019.00178
BACKGROUND: The present study aimed to evaluate the clinical association between cadmium exposure and hearing impairment among the Korean population. METHODS: This retrospective cross-sectional study used the data obtained from the... -
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- ROS Scavenger, Ebselen, Has No Preventive Effect in New Hearing Loss Model Using a Cholesterol-Chelating Agent
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Lee MY, Kabara LL, Swiderski , Raphael Y, Duncan RK, Kim YH
- KMID: 2447576
- J Audiol Otol.
- 2019 Apr;23(2):69-75.
- doi: 10.7874/jao.2018.00255
BACKGROUND AND OBJECTIVES: The antioxidant ebselen will be able to limit or prevent the ototoxicity arising from 2-hydroxypropyl-β-cyclodextrin (HPβCD). Niemann-Pick Type C (NPC) disease is a disorder of lysosomal storage... -
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- Hazardous Alcohol Consumption and the Risk of Hearing Impairment in Adults Based on the Korean National Health and Nutrition Survey: A Retrospective Study
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Park JA, Suh MJ
- KMID: 2447575
- J Audiol Otol.
- 2019 Apr;23(2):63-68.
- doi: 10.7874/jao.2018.00241
BACKGROUND AND OBJECTIVES: To investigate the relationship between hearing impairment and alcohol drinking patterns in South Korean adults. SUBJECTS AND METHODS: Data collection was performed by Korean National Health and Nutrition... -
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- Musical Hallucination Caused by Ceftazidime in a Woman with a Hearing Impairment
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Song CI, Jung YE
- KMID: 2456738
- Clin Psychopharmacol Neurosci.
- 2019 Mar;17(2):326-328.
- doi: 10.9758/cpn.2019.17.2.326
Musical hallucinations remain a poorly understood clinical phenomenon, possibly because these types of hallucination have multiple causes and are rarely the focus of published reports. Here, the case of a... -
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- A Case of Middle Ear Neuroendocrine Adenoma in a Patient with Hearing Loss and Facial Palsy
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Nam W, Kim TH, Kim MB
- KMID: 2442062
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2019 Mar;62(3):182-187.
- doi: 10.3342/kjorl-hns.2017.00528
Middle ear adenoma is a very rare disease which is benign and originates from the middle ear mucosa. Patients of middle ear adenoma usually come to the clinic for unilateral... -
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- Comparison of Aided and Unaided Thresholds and Selection Processes of Contralateral Routing of Signal Hearing Aids and Implantable Bone Conduction Devices in Patients with Asymmetric Hearing Loss
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Kim YH, Lee HJ, Bae MR, Ku JY, Shin CH, Park HJ
- KMID: 2442058
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2019 Mar;62(3):157-164.
- doi: 10.3342/kjorl-hns.2018.00248
BACKGROUND AND OBJECTIVES: We reviewed the selection processes of contralateral routing of signal (CROS) hearing aids (HAs) and bone-conduction (BC) Has, and compared aided and unaided hearing thresholds. SUBJECTS AND METHOD:... -
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- Losartan Prevents Maladaptive Auditory-Somatosensory Plasticity After Hearing Loss via Transforming Growth Factor-β Signaling Suppression
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Mun SK, Han KH, Baek JT, Ahn SW, Cho HS, Chang MY
- KMID: 2437489
- Clin Exp Otorhinolaryngol.
- 2019 Feb;12(1):33-39.
- doi: 10.21053/ceo.2018.00542
OBJECTIVES: Hearing loss disrupts the balance of auditory-somatosensory inputs in the cochlear nucleus (CN) of the brainstem, which has been suggested to be a mechanism of tinnitus. This disruption results... -
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- Mutations in GJB2 as Major Causes of Autosomal Recessive Non-Syndromic Hearing Loss: First Report of c.299-300delAT Mutation in Kurdish Population of Iran
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Azadegan-Dehkordi F, Bahrami T, Shirzad M, Karbasi G, Yazdanpanahi N, Farrokhi E, Koohiyan M, Tabatabaiefar MA, Hashemzadeh-Chaleshtori M
- KMID: 2438178
- J Audiol Otol.
- 2019 Jan;23(1):20-26.
- doi: 10.7874/jao.2018.00185
BACKGROUND AND OBJECTIVES: Autosomal recessive non-syndromic hearing loss (ARNSHL) with genetic origin is common (1/2000 births). ARNSHL can be associated with mutations in gap junction protein beta 2 (GJB2). To... -
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- Genetic Hearing Loss and Gene Therapy
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Carpena NT, Lee MY
- KMID: 2439210
- Genomics Inform.
- 2018 Dec;16(4):e20.
- doi: 10.5808/GI.2018.16.4.e20
Genetic hearing loss crosses almost all the categories of hearing loss which includes the following: conductive, sensory, and neural; syndromic and nonsyndromic; congenital, progressive, and adult onset; high-frequency, low-frequency, or... -
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- Comparison of the Marginal Utility and Disease Burden of Hearing Loss and Other Chronic Diseases
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Kwon OD, Jung SY, Park HY, Peak SK, Cho SH, Cho SJ
- KMID: 2426830
- Korean J Fam Med.
- 2018 Nov;39(6):364-369.
- doi: 10.4082/kjfm.17.0033
BACKGROUND: Compared with other chronic diseases, hearing loss is generally overlooked from the perspective of disease burden. However, hearing loss is emerging as an important issue in the current society.... -
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- Decreased Expression of TRPV4 Channels in HEI-OC1 Cells Induced by High Glucose Is Associated with Hearing Impairment
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Xing Y, Ming J, Liu T, Zhang N, Zha D, Lin Y
- KMID: 2422499
- Yonsei Med J.
- 2018 Nov;59(9):1131-1137.
- doi: 10.3349/ymj.2018.59.9.1131
PURPOSE: Previous reports have shown that hyperglycemia-induced inhibition of transient receptor potential vanilloid sub type 4 (TRPV4), a transient receptor potential ion channel, affects the severity of hearing impairment (HI).... -
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- Outcomes of Direct-to-Consumer Hearing Devices for People with Hearing Loss: A Review
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Tran NR, Manchaiah
- KMID: 2428985
- J Audiol Otol.
- 2018 Oct;22(4):178-188.
- doi: 10.7874/jao.2018.00248
As the population of those with mild to moderate hearing loss increases the need remains for amplification solutions. There is a trend to offer alternative amplification options beyond traditional hearing... -
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- Prognosis of Sudden Low Frequency Hearing Loss during Long-term Follow-up
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Kim JH, Kwak SH, Bae SH, Kim SH, Nam GS
- KMID: 2436254
- Res Vestib Sci.
- 2018 Sep;17(3):102-108.
- doi: 10.21790/rvs.2018.17.3.102
OBJECTIVES: The prognosis of sudden low frequency hearing loss (SLFHL) is relatively good, but recurrences of hearing loss and possible progression to Meniere's disease is still a clinically important concern.... -
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- The Acceptable Noise Level Benefit From Directionality for Listeners With Severe Hearing Loss
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Aghsoleimani M, Jalilvand , Mahdavi ME, Nazeri AR, Kamali M
- KMID: 2429005
- Clin Exp Otorhinolaryngol.
- 2018 Sep;11(3):166-173.
- doi: 10.21053/ceo.2017.01375
OBJECTIVES: Directional microphone technology can enhance the speech intelligibility and listening comfort of listeners with hearing impairment. The main aim of this study is to investigate and compare the benefit... -
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- Clinical Safety and Efficacy of Autologous Bone Marrow-Derived Mesenchymal Stem Cell Transplantation in Sensorineural Hearing Loss Patients
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Lee HS, Kim WJ, Gong JS, Park KH
- KMID: 2415950
- J Audiol Otol.
- 2018 Apr;22(2):105-109.
- doi: 10.7874/jao.2017.00150
Stem cell transplantation represents a promising therapy for several degenerating and necrotic diseases. In several animal studies, we could find hearing restoration after inoculation of the mesenchymal stem cells' as... -
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- The Protective Effect of Egb 761 Against 3-Nitropropionic Acid-Induced Hearing Loss: The Role of Sirtuin 1
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Chang MY, Rhee J, Kim SH, Kim YH
- KMID: 2407786
- Clin Exp Otorhinolaryngol.
- 2018 Mar;11(1):9-16.
- doi: 10.21053/ceo.2017.00626
OBJECTIVES: Local administration of 3-nitropropionic acid (3-NP) to the inner ear induces sensorineural hearing loss. Several studies have shown the otoprotective effects of ginkgo biloba extract EGb 761. Moreover, EGb... -
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