- Generation of Induced Pluripotent Stem Cells from Lymphoblastoid Cell Lines by Electroporation of Episomal Vectors
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Kim M, Park J, Kim S, Han DW, Shin B, Schöler HR, Kim J, Kim KP
- KMID: 2539619
- Int J Stem Cells.
- 2023 Feb;16(1):36-43.
- doi: 10.15283/ijsc22177
Background and Objectives: Lymphoblastoid cell lines (LCLs) deposited from disease-affected individuals could be a valuable donor cell source for generating disease-specific induced pluripotent stem cells (iPSCs). However, generation of iPSCs... -
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- Dexmedetomidine attenuates subarachnoid hemorrhage-induced acute lung injury through regulating autophagy and TLR/NFκB signaling pathway
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Han DW, Oh JE, Lim BJ, Han Y, Song Y
- KMID: 2536123
- Korean J Anesthesiol.
- 2022 Dec;75(6):518-529.
- doi: 10.4097/kja.22165
Background: Acute lung injury (ALI) is the most serious complication of subarachnoid hemorrhage (SAH). We investigated role of autophagy and inflammatory signaling pathways in lung damage and therapeutic effects of... -
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- Robust and Reproducible Generation of Induced Neural Stem Cells from Human Somatic Cells by Defined Factors
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Kwak TH, Hali S, Kim S, Kim J, La H, Kim KP, Hong KH, Shin CY, Kim NH, Han DW
- KMID: 2500568
- Int J Stem Cells.
- 2020 Mar;13(1):80-92.
- doi: 10.15283/ijsc19097
Background and Objectives: Recent studies have described direct reprogramming of mouse and human somatic cells into induced neural stem cells (iNSCs) using various combinations of transcription factors. Although iNSC technology... -
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- Autumn olive (Elaeagnus umbellata Thunb.) berry reduces fasting and postprandial glucose levels in mice
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Kim JI, Baek HJ, Han DW, Yun JA
- KMID: 2434071
- Nutr Res Pract.
- 2019 Feb;13(1):11-16.
- doi: 10.4162/nrp.2019.13.1.11
BACKGROUND/OBJECTIVES: Fasting and postprandial hyperglycemia should be controlled to avoid complications of diabetes mellitus. This study investigated the effects of autumn olive (Elaeagnus umbellata Thunb.) berry (AOB) on fasting and... -
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- Do you believe that processed EEG helps to prevent intraoperative awareness?
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Han DW
- KMID: 2428073
- Korean J Anesthesiol.
- 2018 Dec;71(6):427-429.
- doi: 10.4097/kja.d.18.00309
No abstract available. -
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- A Simulation Study of Propofol Effect-Site Concentration for Appropriate Sedation in Pediatric Patients Undergoing Brain MRI: Pharmacodynamic Analysis
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Na SH, Song Y, Kim SY, Byon HJ, Jung HH, Han DW
- KMID: 2418905
- Yonsei Med J.
- 2017 Nov;58(6):1216-1221.
- doi: 10.3349/ymj.2017.58.6.1216
PURPOSE: We aimed to establish the propofol effect-site concentration (Ce) for appropriate sedation by pharmacodynamic analysis and to determine the propofol Ce during occurrence of sedation-related side effects in pediatric... -
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- Brain and lung: dangerous crosstalk
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Han DW
- KMID: 2377409
- Korean J Anesthesiol.
- 2017 Apr;70(2):116-117.
- doi: 10.4097/kjae.2017.70.2.116
No abstract available. -
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- Pharmacodynamic Estimate of Propofol-Induced Sedation and Airway Obstruction Effects in Obstructive Sleep Apnea-Hypopnea Syndrome
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Koo BN, Shin S, Kim SY, Kang YR, Jeong KH, Han DW
- KMID: 2163637
- Yonsei Med J.
- 2015 Sep;56(5):1408-1414.
- doi: 10.3349/ymj.2015.56.5.1408
PURPOSE: Sedatives must be carefully titrated for patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) as oversedation may lead to disastrous respiratory outcomes. This study aimed to investigate the relations between... -
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- Modeling of Recovery Profiles in Mentally Disabled and Intact Patients after Sevoflurane Anesthesia; A Pharmacodynamic Analysis
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Shin TJ, Noh GJ, Koo YS, Han DW
- KMID: 2070212
- Yonsei Med J.
- 2014 Nov;55(6):1624-1630.
- doi: 10.3349/ymj.2014.55.6.1624
PURPOSE: Mentally disabled patients show different recovery profiles compared to normal patients after general anesthesia. However, the relationship of dose-recovery profiles of mentally disabled patients has never been compared to... -
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- Pharmacokinetic and pharmacodynamic modeling in anesthetic field
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Han DW
- KMID: 1797465
- Anesth Pain Med.
- 2014 Apr;9(2):77-86.
Models are simplified descriptions of true biological processes. Pharmacokinetic/pharmacodynamic (PK/PD) modeling is a mathematical description on the relationship between pharmacokinetics and pharmacodynamics. The PK/PD modeling allows estimation of PK/PD parameters... -
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- Effect of Dexmedetomidine on the Corrected QT and Tp-e Intervals during Spinal Anesthesia
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Kim Y, Kim SY, Lee JS, Kong HJ, Han DW
- KMID: 2386485
- Yonsei Med J.
- 2014 Mar;55(2):517-522.
PURPOSE: The aim of this study is to evaluate the effect of dexmedetomidine on corrected QT (QTc) and Tp-e intervals in patients undergoing spinal anesthesia. MATERIALS AND METHODS: We studied 50... -
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- A brief cardiac arrest due to saline irrigation during surgery for infratentorial cerebellar tumor
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Kim Y, Chang CH, Ham SY, Han DW
- KMID: 1965377
- Korean J Anesthesiol.
- 2013 Dec;65(6 Suppl):S111-S112.
- doi: 10.4097/kjae.2013.65.6S.S111
No abstract available. -
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- Neurobiology, pharmacokinetics and pharmacodynamics of drug abuse
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Kim SY, Lee JS, Han DW
- KMID: 2015672
- J Korean Med Assoc.
- 2013 Sep;56(9):762-770.
- doi: 10.5124/jkma.2013.56.9.762
All drugs of abuse, like neural rewarding behaviors such as sex and eating, increase extra-cellular dopamine (DA) levels in the nucleus accumbens (NA), which is a part of the common... -
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- Conversion of orotracheal to nasotracheal intubation using a fiberoptic bronchoscope in a patient with intraoral hematoma
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Lee HJ, Nam SB, Han DW, Chang CH
- KMID: 2299382
- Korean J Anesthesiol.
- 2013 Apr;64(4):384-385.
- doi: 10.4097/kjae.2013.64.4.384
No abstract available. -
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- Association between opioid receptor gene polymorphism and postoperative pain response in Koreans
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Lee WK, Lee JR, Han DW, Kim KH, Choi SH
- KMID: 1742027
- Anesth Pain Med.
- 2012 Oct;7(4):343-347.
BACKGROUND: The objective of this study was to investigate the association between A118G single nucleotide polymorphism (SNP) of human micro-opioid receptor (OPRM1) gene and the postoperative pain response in Korean... -
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- Heart rate variability predicts the extent of corrected QT interval prolongation after tracheal intubation
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Kim JY, Shim YH, Choi SH, Ham SY, Han DW
- KMID: 2169147
- Anesth Pain Med.
- 2012 Jan;7(1):45-50.
BACKGROUND: Corrected QT (QTc) interval can be modulated by sympathetic and parasympathetic balance. Tracheal intubation causes significant prolongation of the QTc interval due to sympathetic stimulation. This study was designed... -
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- Current status of infertility counseling in Korea
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Kim RH, Lee WM, Kim YJ, Sung YM, Hoh JK, Han DW, Choi YM, Hwang JH
- KMID: 1836747
- Korean J Obstet Gynecol.
- 2011 Oct;54(10):611-617.
- doi: 10.5468/KJOG.2011.54.10.611
OBJECTIVE: The recent fertility decline deepened concern about the emotional side of infertility problems as well as social, ethical, legal and psychological aspect and increased awareness of the importance of... -
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- The effect of beta1-adrenergic receptor gene polymorphism on prolongation of corrected QT interval during endotracheal intubation under sevoflurane anesthesia
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Park K, Jang SB, Kweon TD, Kim JH, Han DW
- KMID: 1766704
- Korean J Anesthesiol.
- 2011 Aug;61(2):117-121.
- doi: 10.4097/kjae.2011.61.2.117
BACKGROUND: The hemodynamic responses to endotracheal intubation are associated with sympathoadrenal activity. Polymorphisms in the beta1-adrenergic receptor (beta1AR) gene can alter the pathophysiology of specific diseases. The aim of this... -
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- Biomechanical Factors Associated with Plantar Fasciitis in Non-obese Patients
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Lee JH, Kim SB, Lee KW, Han DW
- KMID: 2054002
- Korean J Sports Med.
- 2011 Jun;29(1):9-14.
- doi: 10.5763/kjsm.2011.29.1.9
The purpose of this study was to identify the biomechanical factors that correlate with plantar fasciitis in non-obese patients whose body mass index were below 25 kg/m2. The subjects were... -
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- Evaluating the Clinical Symptoms of Neonates with Suspected Dysphagia
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Lee KW, Kim SB, Lee JH, Kim TH, Han DW, Kim MJ
- KMID: 2327342
- J Korean Acad Rehabil Med.
- 2011 Apr;35(2):265-271.
OBJECTIVE: To evaluate the prevalence of dysphagia in neonates who showed abnormal findings on videofluoroscopic swallowing studies (VFSSs), and to compare the accuracy of the clinical evaluation with the VFSS... -
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