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Restoration of the adipogenic gene expression by naringenin and naringin in 3T3-L1 adipocytes

Dayarathne LA, Ranaweera SS, Natraj P, Rajan P, Lee YJ, Han CH

Background: Naringenin and its glycoside naringin are well known citrus flavonoids with several therapeutic benefits. Although the anti-adipogenic effects of naringenin and naringin have been reported previously, the detailed mechanism...
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Impact of Intensivist and Nursing Staff on Critically Ill Patient Mortality: A Retrospective Analysis of the Korean NHIS Cohort Data, 2011–2015

Lee SH, Hong JH, Kim YS, Park EC, Lee SM, Han CH

Purpose: Critical care medicine continues to evolve. However, critical care cases require increasing amount of medical resources. Intensive care unit (ICU) mortality significantly impacts the overall efficiency of healthcare resources within...
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Discovering hidden information in biosignals from patients using artificial intelligence

Yoon D, Jang JH, Choi BJ, Kim TY, Han CH

Biosignals such as electrocardiogram or photoplethysmogram are widely used for determining and monitoring the medical condition of patients. It was recently discovered that more information could be gathered from biosignals...
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Anti-inflammatory effect of sulforaphane on LPS-stimulated RAW 264.7 cells and ob/ob mice

Ranaweera SS, Dissanayake CY, Natraj P, Lee YJ, Han CH

Background: Sulforaphane (SFN) is an isothiocyanate compound present in cruciferous vegetables. Although the anti-inflammatory effects of SFN have been reported, the precise mechanism related to the inflammatory genes is poorly...
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Restoration of the inflammatory gene expression by horse oil in DNCB-treated mice skin

Lee JC, Park GR, Choi BS, Lee Y, Han CH

The present study evaluated the anti-inflammatory effect of horse oil in 2, 4-dinitrochlorobenzene (DNCB)-treated BALB/c mice. After the application of DNCB, the mice showed atopic dermatitis symptoms, including severe erythema,...
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A Case of a Patent Omphalomesenteric Duct Presenting with Meconium Discharge from the Umbilicus

Han CH, Son MW, Song JH

The omphalomesenteric duct is a link between the primitive midgut and the yolk sac. Normally, the duct obliterates around 6 weeks of gestation, yet varying degrees of incomplete obliteration can...
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The Association of Plasma Inflammatory Cytokines with Dementia and Mild Cognitive Impairment

Son KH, Seong SJ, Lee WJ, Hwang JY, Han JH, Jeon YJ, Han CH

OBJECTIVES: The aim of this study was to investigate the association of plasma levels of inflammatory cytokines with dementia and mild cognitive impairment. METHODS: We compared serum levels of tumor necrosis...
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Complete type persistent left cranial vena cava with patent ductus arteriosus in a Bichon Frise dog

Jung HJ, Jang A, Han CH, Bae SW, Lee JH

Persistent left cranial vena cava (PLCVC) is a remnant vessel connected with the coronary sinus and draining into the right atrium. A 3-month-old intact male Bichon Frise was evaluated for...
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Association Between Sarcopenia and Tooth Loss

Han CH, Chung JH

BACKGROUND: The aim of this study was to determine whether the prevalence and extent of periodontal disease and tooth loss are increased in participants with sarcopenia. METHODS: This cross-sectional study included...
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The effects of green tea (Camellia sinensis) flower extracton melanin synthesis in B16-F10 melanoma cells

Dissanayake CY, Moon HH, Yang KM, Lee Y, Han CH

The present study observed the effects of a green tea (Camellia sinensis) flower extract (GTFE) on melanin synthesis in B16-F10 melanoma cells. GTFE exhibited antioxidant activity on 2,2-diphenyl-1-picrylhydrazyl and inhibited...
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Association between Impulsivity and Medical Lethality of Suicide Attempts among Suicide Attempters

Park JW, Suh KH, Son KH, Han JH, Jeon YJ, Jung YJ, Lee WJ, Seong SJ, Han CH, Cho GC, Hwang JY

OBJECTIVES: Although impulsivity has long been thought as an important factor influencing suicidal behaviors, it is unknown whether impulsivity increases the risk of dying from suicidal behaviors and what specific...
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Study on the prevalence and incidence of urolithiasis in Korea over the last 10 years: An analysis of National Health Insurance Data

Jung JS, Han CH, Bae S

PURPOSE: We aimed to analyze the incidence and prevalence of urolithiasis in Korea over the last decade using the National Health Insurance (NHI) sample cohort data. MATERIALS AND METHODS: From January...
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Stress due to End-of-Life Care, Coping Strategies, and Psychological Well-being among Nurses in Neonatal Intensive Care Units

Kwon EH, Ju HO, Jeung EO, Han CH, Im JJ, Lee YR, Jung MS, Park SY

PURPOSE: This study aimed to identify stress levels due to end-of-life care, coping strategies, and psychological well-being among nurses in neonatal intensive care unit, and to investigate the effect of...
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Hangover relieving effect of Sanghwang mushroom mycelium cultured in germinated buckwheat

An YJ, Cho SM, Kim MS, Moon HH, Park DS, Jeon NG, Lee Y, Han CH

The present study was performed to evaluate the hangover relieving effect of germinated buckwheat (GB) and Sanghwang mushroom mycelium cultured in GB (SGB). Both GB and SGB showed 1,1-diphenyl-2-picrylhydrazyl radical...
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Incidence and risk factors of recurrence of overactive bladder symptoms after discontinuation of successful medical treatment

Kim A, Lee KS, Kim TB, Kim HJ, Yoo ES, Yun JH, Kim DY, Jung SG, Lee JT, Kim JM, Oh CK, Shin JH, Jeon SH, Lee SH, Han CH, Lee DH, Cho HJ, Choo MS

PURPOSE: To identify incidence and risk factors of recurrence after discontinuation of successful antimuscarinic therapy in patients with overactive bladder (OAB). MATERIALS AND METHODS: This was a prospective, multicenter trial. Patients...
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Infectious Complications after Prostate Biopsy: A Prospective Multicenter Prostate Biopsy Study

Hwang EC, Yu HS, Jung SI, Kwon DD, Lee SJ, Kim TH, Chang IH, Yoon H, Shim B, Kim KH, Lee D, Huh JS, Lim DH, Jo WJ, Min SK, Lee G, Kim KH, Kim TH, Lee SY, Yang SO, Chung JM, Lee SD, Han CH, Bae SR, Choe HS, Lee SJ, Chung H, Na YG, Yang SW, Park SW, Kim YH, Kim TH, Cho WY, Han JH, Cho YH, Ha US, Park HJ, The Korean Association of Urogenital Tract Infection and Inflammation (KAUTII)

PURPOSE: Recent studies have highlighted an increasing trend of infectious complications due to fluoroquinolone-resistant organisms among men undergoing transrectal prostate biopsy. This study evaluated the current incidence of infective complications...
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Hangover relieving effect of Sanghwang mushroom mycelium extract

Kim MS, An YJ, Lee JC, Park GR, Park DS, Jeon NG, Lee Y, Han CH

This study was conducted to evaluate the hangover relieving effect of Sanghwang mushroom mycelium extract (SME). The extract showed 1,1-diphenyl-2-picrylhydrazyl radical scavenging effect in a concentration-dependent manner and high antioxidant...
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Effects of resveratrol on the insulin signaling pathway of obese mice

Hong HJ, Kang W, Kim DG, Lee DH, Lee Y, Han CH

The present study was conducted to investigate the effects of resveratrol on the insulin signaling pathway in the liver of obese mice. To accomplish this, we administered resveratrol to high...
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Enhancement of Platelet Aggregation by Ursolic Acid and Oleanolic Acid

Kim M, Han CH, Lee MY

  • KMID: 2170644
  • Biomol Ther.
  • 2014 May;22(3):254-259.
The pentacyclic triterpenoid ursolic acid (UA) and its isomer oleanolic acid (OA) are ubiquitous in food and plant medicine, and thus are easily exposed to the population through natural contact...
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Anti-diabetic effects of benfotiamine on an animal model of type 2 diabetes mellitus

Chung KM, Kang W, Kim DG, Hong HJ, Lee Y, Han CH

  • KMID: 1700786
  • Korean J Vet Res.
  • 2014 Mar;54(1):21-26.
Although benfotiamine has various beneficial anti-diabetic effects, the detailed mechanisms underlying the impact of this compound on the insulin signaling pathway are still unclear. In the present study, we evaluated...
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