- Comparison of the efficacy of a combination of high dose metoclopramide and dexamethasone, with that of haloperidol, midazolam and dexamethasone, for the prevention of postoperative nausea and vomiting in laparoscopic gynecologic surgery
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Jee YS, Yoon HJ, Park YS, Kim DW
- KMID: 2436035
- Anesth Pain Med.
- 2018 Jul;13(3):278-285.
- doi: 10.17085/apm.2018.13.3.278
BACKGROUND: This prospective randomized double-blinded study was designed to compare the efficacy of a combination of high dose metoclopramide and dexamethasone with that of haloperidol, midazolam and dexamethasone, for the... -
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- Development and validation of a HPLC-UV method for 4-(4-chlorophenyl)-4-hydroxypiperidine (CPHP), a toxic metabolite of haloperidol, in humans: providing in vivo evidence of CYP3A4-mediated CPHP formation
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Park JY, Shin JG
- KMID: 2351802
- Transl Clin Pharmacol.
- 2016 Sep;24(3):147-151.
- doi: 10.12793/tcp.2016.24.3.147
We developed a high-performance liquid chromatographic procedure for the determination of 4-(4-chlorophenyl)-4-hydroxypiperidine (CPHP), a toxic metabolite of haloperidol, in human. Chromatographic analysis was performed on a reverse-phase Câ‚₈ column with... -
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- Differential Effects of Olanzapine and Haloperidol on MK-801-induced Memory Impairment in Mice
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Song JC, Seo MK, Park SW, Lee JG, Kim YH
- KMID: 2348476
- Clin Psychopharmacol Neurosci.
- 2016 Aug;14(3):279-285.
- doi: 10.9758/cpn.2016.14.3.279
OBJECTIVE: We investigated the differential effects of the antipsychotic drugs olanzapine and haloperidol on MK-801-induced memory impairment and neurogenesis in mice. METHODS: MK-801 (0.1 mg/kg) was administered 20 minutes prior to... -
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- Effects of Clozapine, Haloperidol, and Fluoxetine on the Reversal of Cocaine-Induced Locomotor Sensitization
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Cha SK, Kang UG
- KMID: 2316373
- Psychiatry Investig.
- 2014 Oct;11(4):454-458.
- doi: 10.4306/pi.2014.11.4.454
OBJECTIVE: Repeated treatment with psychostimulants induces sensitization of the dopaminergic system in the brain. Dopaminergic sensitization has been proposed as a mechanism of psychosis. Although antipsychotics block the expression of... -
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- Comparison of the Clinical Efficacy and Safety between Intramuscular Olanzapine and Intramuscular Haloperidol Injection in the Treatment of Delirium
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Lim HK, Paik IH, Oh K, Lee CU, Lee C
- KMID: 2286703
- Korean J Psychopharmacol.
- 2007 Nov;18(6):423-428.
OBJECTIVE: The present study aimed to provide preliminary data on the effectiveness and tolerability of intramuscular (IM) olanzapine and IM haloperidol for patients with delirium. METHODS: Sixty-two patients with delirium were... -
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- Effects of Haloperidol on [Ca2+]i Change in HIT T-15 Insulinoma Cells
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Kim MH, Park KC, Jin SY, Kim DR, Kim MJ, Park KS, Kong ID
- KMID: 2287031
- Korean J Psychopharmacol.
- 2007 Sep;18(5):288-298.
OBJECTIVE: The purpose of this study was to investigate the effects of haloperidol on [Ca2+]i in hamster insulinoma cells (HIT T-15). METHODS: [Ca2+]i levels were measured by calcium imaging techniques, and... -
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- Comparison of Efficacy between Aripiprazole and Haloperidol in the Treatment of Patients with Delirium
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Lee CS, Rim GM, Hahn KH, Kim BJ
- KMID: 2287070
- Korean J Psychopharmacol.
- 2007 Jul;18(4):240-245.
OBJECTIVE: Delirium is defined as an alteration in mental status characterized by brief disturbances in consciousness and attention, cognition, and perception that tend to fluctuate during the course of the... -
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- Risperdal Sachet and Oral Lorazepam versus Intramuscular Haloperidol and Lorazepam Injection for Acute Psychotic Symptom in the Elderly Patients with Organic Mental Disorder
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Youn T
- KMID: 2249212
- Korean J Biol Psychiatry.
- 2007 May;14(2):99-105.
OBJECTIVES: The purpose of present study was to investigate the effect, safety and tolerability of risperdal sachet(oral solution) with lorazepam tablet versus intramuscular haloperidol and lorazepam injection for management of... -
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- The Influences of Risperidone and Clozapine on Body Weight and Glucose Level in Patients with Chronic Schizophrenia: Comparison Study with Haloperidol
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Nam CW, Yang BH, Lee JN
- KMID: 2248981
- Korean J Biol Psychiatry.
- 2004 Nov;11(2):127-135.
OBJECT: The goal of this study was to examine the changes in body weight and glucose levels of the patients treated with risperidone, clozapine or haloperidol in order to compare... -
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- Effects of Haloperidol and Risperidone on the Subjective Quality of Life in Stable Chronic Schizophrenic Patients
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Min SK, Park JK, Suh SY, Kim DK
- KMID: 2340643
- J Korean Neuropsychiatr Assoc.
- 2002 Jan;41(1):76-83.
OBJECTIVE: The purpose of this study is to compare the effects of haloperidol and risperidone on the quality of life in chronic schizophrenic patients and to identify how the... -
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- Effects of Coadministraion of (-)-3-PPP and Haloperidol on the c-fos Expression in the Nucleus Accumbens and Prefrontal Cortex of Rats
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Park KH, Chung YC, Eun HB, Park TW
- KMID: 1607281
- Korean J Psychopharmacol.
- 2001 Jun;12(2):133-139.
OBJECTIVE: The purpose of our study was to measure and compare the c-fos mRNA expression patterns in the nucleus accumbens (NAS) and prefrontal cortex (PFC) of rats after the administration... -
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- Prolactin Response to the Administration of Risperidone and haloperidol in Patients with Schizophrenia and Other Psychotic Disorder
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Chung YC, Park KH, Kim DJ, Park KY
- KMID: 2286939
- Korean J Psychopharmacol.
- 2000 Dec;11(4):343-349.
The purposes of this study were to compare the difference of prolactin responses to risperidone and haloperidol, the sex difference in prolactin responses to each drug and the difference of... -
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- Comparison of Therapeutic Efficacy between Haloperidol and Risperidone in Tic Disorders
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Oh EY, Shin YM, Lee MS, Chung YK, Park JH
- KMID: 2037079
- Korean J Psychopharmacol.
- 2000 Sep;11(3):270-177.
Tourette's syndrome is a heritable neuropsychiatric disorder that begins in childhood. No known medication suppresses tics completely, and the dopamine receptor antagonists-haloperidol and pimozide-for Tourette's syndrome often either produce or... -
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- Effects of Haloperidol Decanoate Treatment on the Rat Brain: Morphological and Neurochemical Study
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Chung YC, Lee KH, Eun HB, Park KY, Uhm TB, Kim HT, Han EH
- KMID: 2286946
- Korean J Psychopharmacol.
- 2000 Jun;11(2):136-144.
Using vacuous chewing movement(VCM) of rats as a possible animal model for tardive dyskinesia(TD), we tried to investigate the effects of haloperidol decanoate treatment on the rat brain: VCM(+) incidence, and morphological... -
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- The Effect of Haloperidol on Regional Cerebral Blood Flow Assessed with 99m-Tc-ECD SPECT In Schizophrenic Patients
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Cheon KA, Lee JD, Min SK, Kim SJ, Ahn SK
- KMID: 2340346
- J Korean Neuropsychiatr Assoc.
- 1999 Jul;38(4):861-872.
OBJECTIVES: Regional cerebral blood flow(rCBF)in schizophrenics is confounded by various factors including medication status. Previously, there have been numerous studies regarding the effects of antipsychotics on rCBF. However, these... -
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- Comparison of Therapeutic Effects actor Side Effects between Nemonapride and Haloperidol Treated Schizophrenic Patients
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Suh KH, Lee HS, Cheong HK, Kim KH, Kim BJ, Chang DW, Kim L
- KMID: 2287011
- Korean J Psychopharmacol.
- 1999 Apr;10(1):40-49.
OBJECTIVE: This open prospective study was performed to investigate the therapeutic efforts and side effects profiles of nemonapride in the schizophrenic patients, and was compared with one of typical anti-psychotics,... -
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- Effects of dopamine and haloperidol on morphine-induced CREB and AP-1 DNA binding activities in differentiated SH-SY5Y human neuroblastoma cells
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Kim SK, Kwon GY
- KMID: 2071825
- Korean J Physiol Pharmacol.
- 1998 Dec;2(6):671-676.
In the present study, we first examined whether the changes in the DNA binding activities of the transcription factors, cAMP response element binding protein (CREB) and activator protein-1 (AP-1) mediate the long-term effects... -
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- Therapeutic Effect of Risperidone on the Refractory Schizophrenia: a Single-Blinded Comparison with Haloperidol
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Lee KW, Yoon TH, Lee C, Jang KY, Seong KS, Song IJ
- KMID: 2340231
- J Korean Neuropsychiatr Assoc.
- 1998 Nov;37(6):1111-1120.
OBJECTIVES: We attempted to investigate clinical efficacy of risperidone a new antipsychotic agent with high safety and without life-threatening side effect such as agranulocytosis, in refractory schizophrenia compared with a... -
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- The Effects of Bethanechol on Anticholinergic Side Effects of Haloperidol
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Son SC, Kim JS, Kim SH, Joe SH, Choi YT
- KMID: 1985342
- Korean J Psychopharmacol.
- 1998 Oct;9(2):153-161.
OBJECTIVES: Haloperidol has been widely used for treating schizophrenia with somewhat limitation due to the side effects. Some of these side effects are anticholinergic side effects such as dry mouth,... -
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- Effects of Nemonapride on Cognitive and Psychomotor Performance and Sedation in Normal Adults: A Comparison with Chlorpromazine, Haloperidol and Placebo
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Yoon BH, Yoon JS, Park SW
- KMID: 1985338
- Korean J Psychopharmacol.
- 1998 Oct;9(2):119-130.
This study was done to compare the effects of nemonapride on cognitive and psychomotor performance and sedation with those of classical antipsychotics in normal adults. Single doses of three antipsychotics... -
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