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Two Types of Mouse Models for Sarcopenia Research: Senescence Acceleration and Genetic Modification Models

Baek KW, Jung YK, Park JS, Kim JS, Hah YS, Kim SJ, Yoo JI

Sarcopenia leads to loss of skeletal muscle mass, quality, and strength due to aging; it was recently given a disease code (International Classification of Diseases, Tenth Revision, Clinical Modification, M62.84)....
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Rodent Model of Muscular Atrophy for Sarcopenia Study

Baek KW, Jung YK, Kim JS, Park JS, Hah YS, Kim SJ, Yoo JI

The hallmark symptom of sarcopenia is the loss of muscle mass and strength without the loss of overall body weight. Sarcopenia patients are likely to have worse clinical outcomes and...
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Genes Expressed in Steroid-exposed Lens Epithelial Cells as Revealed by Polymerase Chain Reaction

Yoo WS, Seo JS, Cho YW, Hah YS, Chung IY, Seo SW, Kim SJ

Purpose: We investigated the expression levels of 84 genes in dexamethasone-exposed human lens epithelial cells using polymerase chain reaction (PCR) array analysis. Methods: The viability and motility of lens epithelial cells...
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The Treatment of Metastatic and Castration-Resistant Prostate Cancer Patients in Korea

Hah YS, Ha US, Jung JW, Park BH, Kim HJ, Kim KH, Yeo JK

The treatment of advanced prostate cancer has rapidly evolved. Androgen deprivation therapy is recognized as the first-line therapy for metastatic disease; however, a substantial proportion of patients will eventually progress...
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Alpha-1 Adrenergic Receptor Blockers for the Treatment of Lower Urinary Tract Symptoms in Women: A Systematic Review and Meta-Analysis

Kim DK, Lee JY, Jung JH, Kim JH, Hah YS, Hong CH, Cho KS

PURPOSE: To assess the effectiveness of alpha-1 adrenergic receptor blockers (α1-blockers) in the treatment of female lower urinary tract symptoms (LUTS). METHODS: A literature search was conducted using the PubMed/MEDLINE, Embase,...
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Role of adjuvant cisplatin-based chemotherapy following radical cystectomy in locally advanced muscle-invasive bladder cancer: Systematic review and meta-analysis of randomized trials

Kim DK, Lee JY, Jung JH, Hah YS, Cho KS

PURPOSE: We purposed to assess the effects of adjuvant chemotherapy (ACH) on survival outcomes in patients with locally advanced muscle-invasive bladder cancer (MIBC) who are treated with radical cystectomy (RC). MATERIALS...
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Time to Disease Recurrence Is a Predictor of Metastasis and Mortality in Patients with High-risk Prostate Cancer Who Achieved Undetectable Prostate-specific Antigen Following Robot-assisted Radical Prostatectomy

Kim DK, Koo KC, Lee KS, Hah YS, Rha KH, Hong SJ, Chung BH

BACKGROUND: Robot-assisted radical prostatectomy (RARP) is a feasible treatment option for high-risk prostate cancer (PCa). While patients may achieve undetectable prostate-specific antigen (PSA) levels after RARP, the risk of disease...
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Overexpression of Neuron-Specific Enolase as a Prognostic Factor in Patients with Gastric Cancer

Park T, Lee YJ, Jeong SH, Choi SK, Jung EJ, Ju YT, Jeong CY, Park M, Hah YS, Yoo J, Ha WS, Hong SC, Ko GH

PURPOSE: Enolase is a cytoplasmic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in the glycolytic pathway. The aim of this study was to investigate whether the overexpression of...
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Cytoprotective Mechanism of Cyanidin and Delphinidin against Oxidative Stress-Induced Tenofibroblast Death

Nam DC, Hah YS, Nam JB, Kim RJ, Park HB

Age-related rotator cuff tendon degeneration is related to tenofibroblast apoptosis. Anthocyanins reduce oxidative stress-induced apoptotic cell death in tenofibroblasts. The current study investigated the presence of cell protective effects in...
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Myeloid deletion of SIRT1 suppresses collagen-induced arthritis in mice by modulating dendritic cell maturation

Woo SJ, Lee SM, Lim HS, Hah YS, Jung ID, Park YM, Kim HO, Cheon YH, Jeon MG, Jang KY, Kim KM, Park BH, Lee SI

The type III histone deacetylase silent information regulator 1 (SIRT1) is an enzyme that is critical for the modulation of immune and inflammatory responses. However, the data on its role...
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Inhibitory Effects for Rheumatoid Arthritis of Dietary Supplementation with Resveratrol in Collagen-induced Arthritis

Cheon YH, Kim HO, Suh YS, Hur JH, Jo W, Lim HS, Hah YS, Sung MJ, Kwon DY, Lee SI

OBJECTIVE: Resveratrol is well-known for its anti-inflammatory, anti-oxidant effects on several diseases. We investigated whether dietary supplementation with resveratrol may suppress joint inflammation and destruction in a mouse model of...
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An Evidence-Based Evaluation of Health Information on Erectile Dysfunction From 10 Nationwide Daily Newspapers in Korea

Hah YS, Lee JY, Lim SK, Cho KS, Choi YD

  • KMID: 2315960
  • Korean J Urol.
  • 2013 Nov;54(11):778-782.
PURPOSE: A rapid growth in the socioeconomic status of Koreans has triggered an unprecedented explosion of health information for the general population. Despite its obvious benefits, this increase in information...
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Role of IL-15 in Sepsis-Induced Skeletal Muscle Atrophy and Proteolysis

Kim HC, Cho HY, Hah YS

BACKGROUND: Muscle wasting in sepsis is associated with increased proteolysis. Interleukin-15 (IL-15) has been characterized as an anabolic factor for skeletal muscles. Our study aims to investigate the role of...
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In vivo Osteogenesis of Cultured Human Periosteal-derived Cells and Polydioxanone/Pluronic F127 Scaffold

Park BW, Lee JH, Oh SH, Kim SJ, Hah YS, Jeon RH, Maeng GH, Rho GJ, Kim JR, Byun JH

  • KMID: 2328038
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2012 Nov;34(6):384-390.
PURPOSE: The purpose of this study is to examine in vivo osteogenesis of cultured human periosteal-derived cells and polydioxanone/pluronic F127 scaffold. METHODS: Two one-year-old miniature pigs were used in this study....
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Induction of Melanogenesis by Rapamycin in Human MNT-1 Melanoma Cells

Hah YS, Cho HY, Lim TY, Park DH, Kim HM, Yoon J, Kim JG, Kim CY, Yoon TJ

  • KMID: 2434679
  • Ann Dermatol.
  • 2012 May;24(2):151-157.
BACKGROUND: Melanogenesis is one of the characteristic parameters of differentiation in melanocytes and melanoma cells. Specific inhibitors of phosphatidylinositol 3-kinase (PI3K), such as wortmannin and LY294002, stimulate melanin production in...
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COMP-Angiopoietin-1 Stimulates Synovial Proliferation but Suppresses Osteoclast by Enhancing Angiogenesis and Osteoblast Maturation in Collagen-Induced Arthritis

Jeong YG, Kim HO, Lim HS, Hah YS, Cho HY, Yu J, Park BH, Koh GY, Lee SI

OBJECTIVE: Angiopoietin-1 (Ang1) is a potent angiogenic factor that can increase synovial angiogenesis and also enhance osteoblast maturation and bone formation. However, its role in rheumatoid arthritis (RA) has not...
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Analysis of Trends and Contents of Nursing Doctoral Dissertations in Korea

Lee KJ, Kang Y, Gu MO, Kim K, Kim O, Suh YO, Suh E, Yang S, Lee EH, Lee JH, Choe MA, Hah YS

PURPOSE: This study aimed to identify contents and trends of Korean nursing doctoral dissertations in terms of research methodology and theoretical characteristics. METHODS: The design of the study was descriptive study...
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Types of Physical Restraint Experience in Mentally Ill Persons: Q Methodological Approach

Ko HS, Hah YS

  • KMID: 2321944
  • J Korean Acad Psychiatr Ment Health Nurs.
  • 2012 Mar;21(1):30-40.
PURPOSE: The purpose of this study was to identify the patterns of physical restraint experience in mentally ill persons. METHODS: Q-methodology, an approach designed to discover patterns in various subjective experiences,...
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Use of Peristeum as a Source of Endothelial-like Cells

Park BW, Kim SW, Kim UK, Hah YS, Kim JH, Kim DR, Sung IY, Cho YC, Son JH, Kim JR, Byun JH

  • KMID: 1722534
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2011 Sep;33(5):385-391.
PURPOSE: The periosteum is a well-known source of osteogenic precursor cells for tissue-engineered bone formation. However, cultured endothelial or endothelial-like cells derived from periosteum have not yet been investigated. This...
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Perceived Stress, Stress Symptoms, and Ways of Coping in Korean College Students

Hah YS, Lee JY

PURPOSE: The purpose of this study was to identify perceived stress level, stress symptoms, and ways of coping and to examine the influences of perceived stress level and ways of...
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