- Heat shock protein 70 increases cell proliferation, neuroblast differentiation, and the phosphorylation of CREB in the hippocampus
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Kwon HJ, Kim W, Jung HY, Kang MS, Kim JW, Hahn KR, Yoo DY, Yoon YS, Hwang IK, Kim DW
- KMID: 2470012
- Lab Anim Res.
- 2019 Dec;35(4):154-164.
- doi: 10.1186/s42826-019-0020-2
In the present study, we investigated the effects of heat shock protein 70 (HSP70) on novel object recognition, cell proliferation, and neuroblast differentiation in the hippocampus. To facilitate penetration into... -
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- MicroRNA-16 inhibits cell proliferation and migration by targeting heat shock protein 70 in heat-denatured dermal fibroblasts
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Zhang C, Dai J, Fan Y, He X, Wei R
- KMID: 2448356
- Korean J Intern Med.
- 2019 May;34(3):634-642.
- doi: 10.3904/kjim.2016.315
BACKGROUND/AIMS: This study aimed to investigate the precise mechanism and function of miR-16 in heat-denatured primary human dermal fibroblasts. METHODS: Primary human dermal fibroblasts were separated from normal human skin samples.... -
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- S100ß, Matrix Metalloproteinase-9, D-dimer, and Heat Shock Protein 70 Are Serologic Biomarkers of Acute Cerebral Infarction in a Mouse Model of Transient MCA Occlusion
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Choi JI, Ha SK, Lim DJ, Kim SD, Kim SH
- KMID: 2420062
- J Korean Neurosurg Soc.
- 2018 Sep;61(5):548-558.
- doi: 10.3340/jkns.2017.0200
OBJECTIVE: Diagnosing acute cerebral infarction is crucial in determining prognosis of stroke patients. Although many serologic tests for prompt diagnosis are available, the clinical application of serologic tests is currently... -
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- Serial Changes of Heat Shock Protein 70 and Interleukin-8 in Burn Blister Fluid
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Yoo K, Suh KY, Choi GH, Kwak IS, Seo DK, Kym D, Yoon H, Cho YS, Kim HO
- KMID: 2394843
- Ann Dermatol.
- 2017 Apr;29(2):194-199.
- doi: 10.5021/ad.2017.29.2.194
BACKGROUND: It has been reported that heat shock protein 70 (HSP70) and interleukin-8 (IL-8) play an important role in cells during the wound healing process. However, there has been no... -
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- The Cytotoxicity of Kahweol in HT-29 Human Colorectal Cancer Cells Is Mediated by Apoptosis and Suppression of Heat Shock Protein 70 Expression
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Choi DW, Lim MS, Lee JW, Chun W, Lee SH, Nam YH, Park JM, Choi DH, Kang CD, Lee SJ, Park SC
- KMID: 2380345
- Biomol Ther.
- 2015 Mar;23(2):128-133.
- doi: 10.4062/biomolther.2014.133
Although coffee is known to have antioxidant, anti-inflammatory, and antitumor properties, there have been few reports about the effect and mechanism of coffee compounds in colorectal cancer. Heat shock proteins... -
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- The expression of FAS-associated factor 1 and heat shock protein 70 in ovarian cancer
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Kang HJ, Moon HS, Chung HW
- KMID: 1841539
- Obstet Gynecol Sci.
- 2014 Jul;57(4):281-290.
- doi: 10.5468/ogs.2014.57.4.281
OBJECTIVE: In this study, we evaluated the expression of FAS-associated factor 1 (FAF1) and heat shock protein 70 (HSP70) in normal ovary and ovarian cancer, and also analyzed the correlation... -
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- Possible Implications of Placental Expressions for Heat Shock Protein 70 and Lectin-like Oxidized Low Density Lipoprotein Receptor-1 on Postnatal Blood Pressure in Their Newborns
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Choi SY, Ahn YM, Min JW, Park HS, Kim YJ, Park EA, Ha EH, Lee HY
- KMID: 2283410
- Korean J Phys Anthropol.
- 2007 Sep;20(3):189-199.
The 'fetal origin' hypothesis propose the alteration in fetal environment result in developmental adaptation, the permanently change in structure, physiology and metabolism, thereby predisposing to cardiovascular, metabolic and endocrine disease... -
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- p53, Heat Shock Protein 70 and Topoisomerase II Expression in Gallbladder Carcinoma
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Kim DC, Roh MS, Jeong JS
- KMID: 1593780
- Korean J Pathol.
- 2006 Dec;40(6):432-438.
BACKGROUND: The present study was designed to investigate the expression of p53, Heat Shock Protein 70 (HSP70), and Topoisomerase (Topo) II alpha in the preneoplastic lesions and carcinomas of the... -
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- Effect of the Heat Shock Protein 70 on the Adjuvanticity Induced by a Bacterial Flagellin of Vibrio ulnificus
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Lee SE, Bae SJ, Kim SY, Kim YR, Rhee JH
- KMID: 1574182
- J Bacteriol Virol.
- 2005 Dec;35(4):299-306.
Recently we have shown that a bacterial flagellin, Vibrio vulnifiucs FlaB (Vv-FlaB), has a strong adjuvant activity to induce protective immune response. In order to investigate the adjuvanticity of Vv-FlaB,... -
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- Effects of Heat Shock Protein 70 (HSP70) Induction after Lipopoly?saccharide Exposure on the IL-6 Production and the Cell Viability after Subsequent Lipopolysaccharide Challenge in Murine Alveolar Epithelial Cells
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Lee JM, Kim JS, Kim YK, Kim SJ, Lee SY, Kwon SS, Park SH
- KMID: 2318550
- Tuberc Respir Dis.
- 2005 Apr;58(4):375-384.
BACKGROUND AND AIMS: Pre-induction of heat shock protein 70 (HSP70) is known to effectively attenuate the lipopolysaccharide (LPS)-induced inflammatory response in lung tissue. However, it is unclear if HSP70 induction... -
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- Protective Efficacy of Recombinant Proteins Adenylate Kinase, Nucleoside Diphosphate Kinase, and Heat-Shock Protein 70 against Mycobacterium tuberculosis Infection in Mice
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Lee SH, Lee EG, Kim SY, Cho SN, Park YK, Bai GH
- KMID: 2318536
- Tuberc Respir Dis.
- 2005 Feb;58(2):142-151.
BACKGROUND: Priming and boosting vaccination strategy has been widely explored for new vaccine development against tuberculosis. As an effort to identify other vaccine candidates, this study was initiated to evaluate... -
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- The Study about Expression and Regulation Mechanism of Heat Shock Protein 70 by Arisostatins A in Caki Cell Line of Renal Cell Carcinoma
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Lee H, Kwon TK, Park JW, Lee KS
- KMID: 2293956
- Korean J Urol.
- 2005 Feb;46(2):181-189.
PURPOSE: The events of cell stress and cell death are linked, with the heat shock proteins (Hsps) induced in response to stress appearing to function at key regulatory points in... -
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- Heat-Shock Protein 70 Attenuates Caspase-3 Activation and DNA Fragmentation Following Focal Cerebral Ischemia
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Lee SH, Kwon HM, Kim YJ, Lee KM, Kim M, Yoon BW
- KMID: 2343115
- J Korean Neurol Assoc.
- 2004 Dec;22(6):623-630.
BACKGROUND: Recently, HSP70 has been shown to act as an inhibitor of apoptotic pathways in the cell culture following heat shock; however, little information is available on the mechanism of... -
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- Effect of Etomidate on the Expressions of c-JUN and Heat Shock Protein 70 Induced by Kainic Acid in Rats
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Lee JH, Lee YM, Chang BJ, Park SJ, Lee JY, Kim JU, Ku SW
- KMID: 2237538
- Korean J Anesthesiol.
- 2004 Aug;47(2):253-259.
- doi: 10.4097/kjae.2004.47.2.253
BACKGROUND: The present investigation was undertaken to evaluate the neuroprotective effect of etomidate against kainic acid (KA) induced neurotoxicity in rats by Western immunoblotting for heat shock protein 70 (HSP-70),... -
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- Fluoxetine Pretreatment Exert Time-Dependent Inhibits the Dexamethasone-Mediated Heat Shock Protein 70 Expression in Rat C6 Glioma Cells
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Lee JS, Yang BH, Kim SH, Choi MR, Chai YG
- KMID: 2286877
- Korean J Psychopharmacol.
- 2004 Mar;15(1):66-74.
OBJECTIVE: The aim of this study was to examine the effect of dexamethasone and fluoxetine on the expression of 70 kDa heat shock protein (HSP70) in C6 glioma cells. METHODS:... -
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- Effects of Temperature Change on Heat Shock Protein 70 Expression in Rat Testes
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Park SH, Park K, Park YI
- KMID: 2293759
- Korean J Urol.
- 2003 Feb;44(2):186-191.
PURPOSE: It has been reported that exposure of the testes to elevated temperatures results in decreased spermatogenesis. The aim of this study was to investigate the effects of temperature change... -
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- Expression of Heat Shock Protein 70 in Ipsilateral Rat Kidney with Unilateral Partial Ureteral Obstruction
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Jeong WJ, Song KH, Kim KJ
- KMID: 2292526
- Korean J Urol.
- 2002 Dec;43(12):1065-1069.
PURPOSE: A partial ureteral obstruction is a common clinical finding. Heat shock proteins (HSPs) maintain homeostasis, and protect cells from various injuries caused by physical and biochemical stresses. Particularly, heat... -
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- The Role of Heat Shock Protein 70 in the Pancreatic Trypsinogen Activation: Studies in Hsp70.1 Knock-out Mice
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Hwang JH, Kim YT, Yoon YB, Jeong JB, Bae CJ, Seo JS, Kim CY
- KMID: 1647238
- Korean J Gastroenterol.
- 2002 Nov;40(5):326-333.
BACKGROUND/AIMS: Heat shock proteins (Hsps) are expressed in the cell as a response to the external stimulation such as heat. There are some reports that the Hsp (i.e. Hsp70) is... -
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- Association of Heat Shock Protein 70 Gene Polymorphisms with Schizophrenia
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Kim JJ, Lee KU, Lee SJ, Kwon OJ, Lee CU, Lee C, Paik IH, Han JH
- KMID: 2340757
- J Korean Neuropsychiatr Assoc.
- 2002 Sep;41(5):814-822.
OBJECTIVES: Contemporary understanding of schizophrenia has evolved over the last century, yet its pathogenesis is not clear. Environmental stresses in early gestational period, which in turn, can cause neurodevelopmental abnormalities,... -
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- Induction of Heat Shock Protein 70 after Experimental Pulpal Exposure in Rats
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Baik JW, Baek SH, Yoon TG, Kim HJ, Yum KW
- KMID: 2032002
- Korean J Anesthesiol.
- 2002 Jun;42(6):831-836.
- doi: 10.4097/kjae.2002.42.6.831
BACKGROUND: Inducible heat shock protein 70s (iHSP70) are expressed by stressful stimuli that result in protein denaturation, and are thought to assist in the maintenance of cellular integrity and... -
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