- A Case of Cutaneous Leukocytoclastic Vasculitis Associated with Granulocyte Colony-Stimulating Factor: An Unusual Presentation
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Yoon D, Byun HJ, Oh SJ, Park JH, Lee DY
- KMID: 2471345
- Ann Dermatol.
- 2020 Apr;32(2):164-167.
- doi: 10.5021/ad.2020.32.2.164
Drug-induced vasculitis is an inflammation of small-sized blood vessel caused by the use of drugs. It accounts for approximately 10% of acute cutaneous vasculitis. Propylthiouracil, hydralazine, and allopurinol have been... -
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- Delta Neutrophil Index as an Early Marker of Sepsis in Burn Patients
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Kim CM, Ha CM
- KMID: 2469247
- J Korean Burn Soc.
- 2019 Dec;22(2):38-44.
- doi: 10.0000/jkbs.2019.22.2.38
PURPOSE: The immature granulocyte count has been reported to be a marker of infection and sepsis. The difference in leukocyte subfractions (delta neutrophil index, DNI) in ADVIA 2120 reflects the... -
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- Clonal Cell Proliferation in Paroxysmal Nocturnal Hemoglobinuria: Evaluation of PIGA Mutations and T-cell Receptor Clonality
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Park J, Kim M, Kim Y, Han K, Chung NG, Cho B, Lee SE, Lee JW
- KMID: 2450966
- Ann Lab Med.
- 2019 Sep;39(5):438-446.
- doi: 10.3343/alm.2019.39.5.438
BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired pluripotent hematopoietic stem cell disorder associated with an increase in the number of glycosyl-phosphatidyl inositol (GPI)-deficient blood cells. We investigated PNH clonal... -
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- Comparison of the virulence of Streptococcus pneumoniae in ICR mouse stocks of three different origins
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Kim JY, Seo SM, Lee HK, Kim HW, Choi YK
- KMID: 2456057
- Lab Anim Res.
- 2019 Jun;35(1):23-29.
- doi: 10.1186/s42826-019-0002-4
Streptococcus pneumoniae causes many people to suffer from pneumonia, septicemia, and other diseases worldwide. To identify the difference in susceptibility of and treatment efficacy against S. pneumoniae in three ICR... -
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- Evaluation of Time and Temperature Stability of Paroxysmal Nocturnal Hemoglobinuria Cells by Flow Cytometry
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Lee SH, Bang HI, Shin YJ, Shin WY, Kim J, Park R, Shin JW, Choi TY
- KMID: 2441824
- Lab Med Online.
- 2019 Apr;9(2):57-62.
- doi: 10.3343/lmo.2019.9.2.57
BACKGROUND: Flow cytometry analysis of paroxysmal nocturnal hemoglobinuria (PNH) is significantly affected by the methodology used. The lack of data on the effect of age and refrigeration on PNH clone... -
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- Analysis of hematologic parameters of donors, patients, and granulocyte concentrates to predict successful granulocyte transfusion
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Lee JM, Choi SJ, Kim HS, Yang M, Kim Y, Lee JW, Lim J
- KMID: 2451056
- Blood Res.
- 2019 Mar;54(1):52-56.
- doi: 10.5045/br.2019.54.1.52
BACKGROUND: Granulocyte transfusion (GTx) is performed as a supportive therapy in severe neutropenic patients caused by various conditions. The study aimed to analyze the hematologic parameters of donors, patients, and... -
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- Hematopoiesis Activity of Sambucus javanica on Chloramphenicol-induced Aplastic Anemia Mouse Model
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Putra WE, Rifa'i M
- KMID: 2443105
- Nat Prod Sci.
- 2019 Mar;25(1):59-63.
- doi: 10.20307/nps.2019.25.1.59
Hematopoiesis has a pivotal role in the maintenance of body homeostasis. Ironically, several hematological disorder caused by chemicals, drugs, and other environmental factors lead to severe bone marrow failure. Current... -
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- Comparison of High Sensitivity and Conventional Flow Cytometry for Diagnosing Overt Paroxysmal Nocturnal Hemoglobinuria and Detecting Minor Paroxysmal Nocturnal Hemoglobinuria Clones
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Park SH, Jeong J, Lee SH, Yoo DW, Choi Y, Jo JC, Lim JH
- KMID: 2425970
- Ann Lab Med.
- 2019 Mar;39(2):150-157.
- doi: 10.3343/alm.2019.39.2.150
BACKGROUND: High sensitivity flow cytometry (HS-FCM) was recently developed for diagnosing paroxysmal nocturnal hemoglobinuria (PNH). We compared its performance with conventional flow cytometry (C-FCM) for diagnosing overt PNH and detecting... -
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- Development of a Novel Flow Cytometry-Based System for White Blood Cell Differential Counts: 10-color LeukoDiff
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Park D, Chang J, Kahng J, Park H, Jo I, Kim Y, Han K
- KMID: 2425969
- Ann Lab Med.
- 2019 Mar;39(2):141-149.
- doi: 10.3343/alm.2019.39.2.141
BACKGROUND: Flow cytometry (FCM) is commonly used to identify many cell populations. We developed a white blood cell (WBC) differential counting system for detecting abnormal cells using FCM incorporating 10... -
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- Molecular Detection and Phylogenetic Analysis of Anaplasma phagocytophilum in Horses in Korea
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Seo MG, Ouh IO, Choi E, Kwon OD, Kwak D
- KMID: 2441616
- Korean J Parasitol.
- 2018 Dec;56(6):559-565.
- doi: 10.3347/kjp.2018.56.6.559
The identification and characterization of pathogenic and zoonotic tick-borne diseases like granulocytic anaplasmosis are essential for developing effective control programs. The differential diagnosis of pathogenic Anaplasma phagocytophilum and non-pathogenic A.... -
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- Antiviral and Anti-Inflammatory Activities of Pochonin D, a Heat Shock Protein 90 Inhibitor, against Rhinovirus Infection
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Song JH, Shim A, Kim YJ, Ahn JH, Kwon BE, Pham TT, Lee J, Chang SY, Ko HJ
- KMID: 2427511
- Biomol Ther.
- 2018 Nov;26(6):576-583.
- doi: 10.4062/biomolther.2017.233
Human rhinoviruses (HRV) are one of the major causes of common cold in humans and are also associated with acute asthma and bronchial illness. Heat-shock protein 90 (Hsp90), a molecular... -
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- Dapsone modulates lipopolysaccharide-activated bone marrow cells by inducing cell death and down-regulating tumor necrosis factor-α production
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Kwon MJ, Joo HG
- KMID: 2427022
- J Vet Sci.
- 2018 Nov;19(6):744-749.
- doi: 10.4142/jvs.2018.19.6.744
Dapsone, an antibiotic, has been used to cure leprosy. It has been reported that dapsone has anti-inflammatory activity in hosts; however, the anti-inflammatory mechanism of dapsone has not been fully... -
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- Delta Neutrophil Index as an Early Marker for Distinguishing Myeloid from Childhood Acute Leukemia
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Hong JP, Kim S, Kim BR, Yoon SH, Hahn SM, Kim MK
- KMID: 2435404
- Clin Pediatr Hematol Oncol.
- 2018 Oct;25(2):128-135.
- doi: 10.15264/cpho.2018.25.2.128
BACKGROUND: The accurate and early diagnosis of acute myeloid leukemia (AML) is important to choose proper treatment option depending on the risk stratification. The delta neutrophil index (DNI) is a... -
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- Serial Changes in Mannose-Binding Lectin in Patients with Sepsis
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Huh JW, Song K, Kim HJ, Yum JS, Hong SB, Lim CM, Koh Y
- KMID: 2420564
- Tuberc Respir Dis.
- 2018 Oct;81(4):305-310.
- doi: 10.4046/trd.2017.0060
BACKGROUND: Mannose-binding lectin (MBL) deficiency leads to increased susceptibility to infection. We investigated whether serial changes in MBL levels are associated with the prognosis of patients diagnosed with septic shock,... -
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- Flow-Cytometric Analysis of HNA-2 Expression and Phenotypes Among Thai Blood Donors
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Nathalang , Siriphanthong K, Petvises S, Jeumjanya
- KMID: 2408076
- Ann Lab Med.
- 2018 Jul;38(4):362-366.
- doi: 10.3343/alm.2018.38.4.362
BACKGROUND: Antibodies specific to human neutrophil antigen (HNA), especially HNA-2, are implicated in various conditions, including neonatal alloimmune neutropenia, febrile non-hemolytic transfusion reactions, and transfusion-related acute lung injury. The distribution... -
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- Busulfan plus melphalan versus high-dose melphalan as conditioning regimens in autologous stem cell transplantation for newly diagnosed multiple myeloma
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Byun JM, Lee J, Shin SJ, Kang M, Yoon SS, Koh Y
- KMID: 2451027
- Blood Res.
- 2018 Jun;53(2):105-109.
- doi: 10.5045/br.2018.53.2.105
BACKGROUND: High-dose melphalan (HDMEL) represents the standard conditioning regimen before autologous stem cell transplant (ASCT) in multiple myeloma (MM), but recent updates have suggested combination of melphalan with bulsulfan (BUMEL)... -
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- Investigation of Immune-Regulatory Effects of Mageumsan Hot Spring via Protein Microarray In Vitro
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Hahn HJ, Kim JS, Kim YH, Lee YB, Yu DS, Kim JW
- KMID: 2419174
- Ann Dermatol.
- 2018 Jun;30(3):322-330.
- doi: 10.5021/ad.2018.30.3.322
BACKGROUND: Empirical evidences for efficacy of hot spring (HS) water in inflammatory skin disorders have not been substantiated with sufficient, immunological “hard evidenceâ€. Mageumsan HS water, characterized by its weakly-alkaline... -
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- Delta Neutrophil Index Is Associated with Vasculitis Activity and Risk of Relapse in ANCA-Associated Vasculitis
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Yoo J, Ahn SS, Jung SM, Song JJ, Park YB, Lee SW
- KMID: 2407863
- Yonsei Med J.
- 2018 May;59(3):397-405.
- doi: 10.3349/ymj.2018.59.3.397
PURPOSE: Delta neutrophil index (DNI) represents the immature granulocytes count associated with neutrophil-consumption. We investigated whether DNI might be associated with Birmingham vasculitis activity score (BVAS) at diagnosis and could... -
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- Extended Culture of Bone Marrow with Granulocyte Macrophage-Colony Stimulating Factor Generates Immunosuppressive Cells
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Na HY, Sohn M, Ryu SH, Choi W, In H, Shin HS, Park CG
- KMID: 2410160
- Immune Netw.
- 2018 Apr;18(2):e16.
- doi: 10.4110/in.2018.18.e16
Bone marrow-derived dendritic cells (BM-DCs) are generated from bone marrow (BM) cells cultured with granulocyte macrophage-colony stimulating factor (GM-CSF) for a week. In this study we investigated the effect of... -
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- A Prospective Study of Eosinophilic Esophagitis and the Expression of Tight Junction Proteins in Patients with Gastroesophageal Reflux Disease Symptoms
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Okimoto K, Arai M, Ishigami H, Saito K, Minemura S, Maruoka D, Matsumura , Nakagawa T, Katsuno T, Suzuki M, Nakatani Y, Yokosuka O
- KMID: 2404714
- Gut Liver.
- 2018 Jan;12(1):30-37.
- doi: 10.5009/gnl16600
BACKGROUND/AIMS: Eosinophilic esophagitis (EoE) is often erroneously diagnosed as gastroesophageal reflux disease (GERD). The aim of this study is to investigate the prevalence of EoE and the expression of tight... -
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