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Intelectin-1 and Endocrinological Parameters in Women with Polycystic Ovary Syndrome: Effect of Insulin Resistance

Al-Fartosy AJM, Awad NA, Mohammed A

OBJECTIVES: We aimed to evaluate the effect of insulin resistance (IR) on serum Intelectin-1 and endocrinological hormones levels in obese and non-obese women with and without polycystic ovary syndrome (PCOS)...
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Sex Differences in Gut Microbiota

Kim YS, Unno T, Kim BY, Park MS

Humans carry numerous symbiotic microorganisms in their body, most of which are present in the gut. Although recent technological advances have produced extensive research data on gut microbiota, there are...
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Obstructive Sleep Apnea in Women

Ayub S, Won CH

Obstructive sleep apnea is known to be more prevalent in men. In women the prevalence varies throughout her life span as she goes through different stages; puberty, reproductive years, pregnancy...
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Diabetes and Cancer: Cancer Should Be Screened in Routine Diabetes Assessment

Suh S, Kim KW

Cancer incidence appears to be increased in both type 1 and type 2 diabetes mellitus (DM). DM represents a risk factor for cancer, particularly hepatocellular, hepatobiliary, pancreas, breast, ovarian, endometrial,...
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Epidemiological characteristics of breast cancer in Koreans

Park SK

In the ranking of cancer incidence in the year, female breast cancer was the highest cancer after thyroid cancer in 2004–2015, and became the most common cancer in 2016, exceeding...
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The effects of exposure to lead, cadmium and mercury on follicle-stimulating hormone levels in men and postmenopausal women: data from the Second Korean National Environmental Health Survey (2012–2014)

Lee TW, Kim DH, Ryu JY

BACKGROUND: Follicle-stimulating hormone (FSH), a gonadotropin secreted by the pituitary gland, is a representative secondary sex hormone and an important indicator of reproductive function. The effects of heavy metals such...
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Sex hormones alter the response of Toll-like receptor 3 to its specific ligand in fallopian tube epithelial cells

Zandieh Z, Amjadi F, Vakilian H, Aflatoonian K, Amirchaghmaghi E, Fazeli A, Aflatoonian R

OBJECTIVE: The fallopian tubes play a critical role in the early events of fertilization. The rapid innate immune defense is an important part of the fallopian tubes. Toll-like receptor 3...
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Sex-specific Behavioral Features of Rodent Models of Autism Spectrum Disorder

Jeon SJ, Gonzales E, Mabunga DF, Valencia S, Kim DG, Kim Y, Adil KJ, Shin D, Park D, Shin CY

Sex is an important factor in understanding the clinical presentation, management, and developmental trajectory of children with neuropsychiatric disorders. While much is known about the clinical and neurobehavioral profiles of...
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Sex-Gender Differences in Irritable Bowel Syndrome

Kim YS, Kim N

  • KMID: 2422845
  • J Neurogastroenterol Motil.
  • 2018 Oct;24(4):544-558.
  • doi: 10.5056/jnm18082
Because of the sex-gender differences that are shown in a diversity of physiological and psychological factors, it can be speculated that the clinical presentation of symptoms as well as treatment...
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Testosterone and Sarcopenia

Shin MJ, Jeon YK, Kim IJ

Aging affects metabolism, leading to physiological and functional impairments, and is also related to changes in body composition, including reduced skeletal muscle mass and increased body fat. These changes are...
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Unsettled Issues and Future Directions for Research on Cardiovascular Diseases in Women

Regitz-Zagrosek V

Biological sex (being female or male) significantly influences the course of disease. This simple fact must be considered in all cardiovascular diagnosis and therapy. However, major gaps in knowledge about...
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Sex Differences in Cancer: Epidemiology, Genetics and Therapy

Kim HI, Lim H, Moon A

The incidence and mortality of various cancers are associated with sex-specific disparities. Sex differences in cancer epidemiology are one of the most significant findings. Men are more prone to die...
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A Comparative Analysis of Pre- and Postmenopausal Females with Periodontitis and Its Response to a Non Invasive Clinical Approach

Prasanna J, Sumadhura , Karunakar

OBJECTIVES: The influence of sex steroid hormones on periodontium can be knockdown with good plaque control. The aim of the present study was to evaluate periodontal status in pre- and...
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Increased Serum G Protein-coupled Estrogen Receptor 1 Levels and Its Diagnostic Value in Drug Naïve Patients with Major Depressive Disorder

Findikli E, Kurutas EB, Camkurt MA, Karaaslan , Izci F, Fındıklı HA, Kardaş S, Dag B, Altun H

OBJECTIVE: The facts that depression is more prevalent in females than in males and females are exposed to depression more commonly during certain hormonal fluctuating periods indicate the role of...
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Sex-dependent Depot Differences in Adipose Tissue Development and Function; Role of Sex Steroids

Lee MJ, Fried SK

Men and women are different in their fat mass and distribution pattern. The gynoid-type fat distribution, accumulation in lower-body, is considered to be protective while the android-type accumulation in upper-body,...
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Sex-specific regulation of immune responses by PPARs

Park HJ, Choi JM

The prevalence of autoimmune, infectious and metabolic diseases is different for men and women owing to the respective ability of their immune systems to respond to self and foreign antigens....
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Effects of Estradiol on the Paracrine Regulator Expression of In Vitro Maturated Murine Ovarian Follicles

Kim YJ, Park KE, Kim YY, Kim H, Ku SY, Suh CS, Kim SH, Choi YM

The preservation of female germ cells is important in the individuals with ovarian dysfunction and failure. For this purpose, ovarian follicle in vitro maturation (OFIVM) is an important technology for...
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The Role of Visceral Hypersensitivity in Irritable Bowel Syndrome: Pharmacological Targets and Novel Treatments

Farzaei MH, Bahramsoltani R, Abdollahi , Rahimi R

  • KMID: 2433449
  • J Neurogastroenterol Motil.
  • 2016 Oct;22(4):558-574.
  • doi: 10.5056/jnm16001
Irritable bowel syndrome (IBS) is the most common disorder referred to gastroenterologists and is characterized by altered bowel habits, abdominal pain, and bloating. Visceral hypersensitivity (VH) is a multifactorial process...
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17α-hydroxylase Deficiency Mimicking Hyperaldosteronism by Aldosterone-producing Adrenal Adenoma

Cho YK, Oh H, Kang SM, An S, Huh JY, Lee JH, Lee WJ

17α-hydroxylase deficiency is a rare cause of congenital adrenal hyperplasia and is characterized by primary amenorrhea, delayed puberty and hypertension. Although 17α-hydroxylase deficiency mimics mineralocorticoid-induced hypertension, impaired sexual development can...
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The role of sex steroid hormones in the pathophysiology and treatment of sarcopenia

Kim YJ, Tamadon A, Park HT, Kim H, Ku SY

Sex steroids influence the maintenance and growth of muscles. Decline in androgens, estrogens and progesterone by aging leads to the loss of muscular function and mass, sarcopenia. These steroid hormones...
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