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Cystic Neck Mass in an Adult: Unusual Manifestation of a Mediastinal Mature Teratoma

Lee YJ, Jeong YJ, Suh HB, Kim HJ, Lee BJ, I HS, Roh J, Yeom JA

Anterior mediastinal teratomas are congenital tumors containing derivatives of all three germ layers. They usually grow slowly and are often detected incidentally by imaging studies. We describe the case of...
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A Case of Teratoma of Thyroid Gland in Adolescence

Lee YC, Jeong SJ, Lee SJ, Kim CH, Lee YH, Lee JE, Seo HJ

Benign teratomas of the thyroid are very rare in adolescence and adults. In this review, we report a case of 14-year-old Korean girl with huge neck mass. She presented with...
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Spatial Allocation and Specification of Cardiomyocytes during Zebrafish Embryogenesis

Fukui H, Chiba A, Miyazaki T, Takano H, Ishikawa H, Omori T, Mochiuzki

Incomplete development and severe malformation of the heart result in miscarriage of embryos because of its malfunction as a pump for circulation. During cardiogenesis, development of the heart is precisely...
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Understanding of Human Embryo Development for Teratogen Counselling

Chun Y, Lee H

Human embryology is the study of development from a single cell to a baby in 9 months. Implantation occurs at the end of the first week of development. The second...
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Motor neurons derived from ALS-related mouse iPS cells recapitulate pathological features of ALS

Park JH, Park HS, Hong S, Kang S

Amyotrophic lateral sclerosis (ALS) is a late-onset progressive neurodegenerative disease characterized by the loss of motor neurons in the spinal cord and brain. Mutations in Cu/Zn superoxide dismutase 1 (SOD1)...
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Induced Pluripotent Stem (iPS) Cells in Dentistry: A Review

Malhotra N

iPS cells are derived from somatic cells via transduction and expression of selective transcription factors. Both viral-integrating (like retroviral) and non-integrating (like, mRNA or protein-based) techniques are available for the...
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A Case of Primary Mature Teratoma of the Rectum

Park HS, Hong SG, Jung SY, Kang SM, Lee K, Yu DW

  • KMID: 1910331
  • Soonchunhyang Med Sci.
  • 2014 Jun;20(1):27-30.
A mature teratoma is a tumor composed of normal derivatives of all three germ layers, and usually occurs in ovaries, testes, or mediastinum. Mature teratoma of the gastrointestinal tract occurs...
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Benign Teratoma of the Thyroid Gland

Oak CY, Kim HK, Yoon TM, Lim SC, Park HB, Park HC, Han MG, Kang HC

Although pathology reports of thyroid tissue in ovarian teratomas are abundant, benign teratomas of the thyroid are extremely rare in adolescents and adults. Therefore, their clinical characteristics are still not...
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Assessment of Developmental Toxicants using Human Embryonic Stem Cells

Hong EJ, Jeung EB

  • KMID: 2317839
  • Toxicol Res.
  • 2013 Dec;29(4):221-227.
Embryonic stem (ES) cells have potential for use in evaluation of developmental toxicity because they are generated in large numbers and differentiate into three germ layers following formation of embryoid...
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Neuronal Differentiation of a Human Induced Pluripotent Stem Cell Line (FS-1) Derived from Newborn Foreskin Fibroblasts

Kwon J, Lee N, Jeon I, Lee HJ, Do JT, Lee DR, Oh SH, Shin DA, Kim A, Song J

  • KMID: 1735408
  • Int J Stem Cells.
  • 2012 Nov;5(2):140-145.
Isolation of induced pluripotent stem cells (iPSCs) from fully differentiated somatic cells has revolutionized existing concepts of cell differentiation and stem cells. Importantly, iPSCs generated from somatic cells of patients...
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A Case of Adrenal Teratoma

Kim JY, Cho YZ, Lee KW, Lim DM, Park KY, Kim BJ

Teratoma is a congenital tumor containing tissues derived from all germ layers. Teratoma in the region of the adrenal gland is a very uncommon retroperitoneal tumor. Only 7 cases of...
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Chemical compound 31002 stimulates cardiomyogenic differentiation of embryonic stem cells

Kim EK, Son MY, Kang Y, Lee CH, Kim HR, Won Y, Yoon W, Kim HC, Nam KH

Embryonic stem cells (ESCs) are an emerging source for cell-based therapies aimed at repairing damaged organ tissues; however, the efficiency of directed differentiation is low and refinement of differentiation protocols...
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Mature Teratoma in the Adrenal Gland

Cha EJ

A teratoma is a germ-cell tumor composed of tissue components representing derivatives of three germ layers. A teratoma in the region of adrenal gland is a rare retroperitoneal tumor. We...
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Mature Cystic Teratoma of the Fallopian Tube: A Brief Case Report

Sung WJ, Kim JM, Kim MJ

Mature cystic teratomas of the fallopian tube are unusual, being almost incidentally identified. Here we describe a case of mature cystic teratoma arising in the fallopian tube, in a 44-year-old...
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Establishment and Characterization of Multipotent Germ Line Stem Cells (MGSCs) from Neonatal Mouse Testis

Han SC, Song H, Jun JH

  • KMID: 1483347
  • Korean J Reprod Med.
  • 2008 Mar;35(1):39-48.
OBJECTIVE: The aim of this study was to investigate whether multipotent germline stem cells (MGSCs) can be established from neonatal mouse testis. METHODS: Various cells containing MGSCs were collected from neonatal...
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Mature Teratoma in the Cerebellar Hemisphere of an Adult

Park KB, Park HS, Lee JI, Suh YL

Intracranial teratomas are diagnosed mostly in young population and usually involve midline structure. We report a case of mature teratoma in an adult patient with unusual location in cerebellar hemisphere....
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A Case of Trichoblastic Fibroma at the Cheek

Oh HB, Lee KH, Lee SR, Kang NH, Suh KS

  • KMID: 2098440
  • J Korean Soc Plast Reconstr Surg.
  • 2006 Jul;33(4):495-498.
PURPOSE: Trichoblastic fibroma originates from hair germ layer tumor which is a benign tumor mixture of epidermal and mesodermal factor. Trichoblastic fibroma was found only in adults and showed equal...
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Establishment of Embryonic Stem Cell Line from Isolated Blastomeres from Mouse Preimplantation Embryos

Lim CK, Sung JH, Choi HW, Cho JW, Shin MR, Jun JH

  • KMID: 1511387
  • Korean J Fertil Steril.
  • 2006 Mar;33(1):25-34.
OBJECTIVE: The aim of this study was to investigate whether embryonic stem (ES) cells can be established from isolated blastomeres of mouse embryos. METHODS: Blastomeres were separated from mouse (C57Bl/6J) 2-...
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A case of presacral teratoma in an adult female

Ha MT, Cho IM, Joung SY, Park JK, Shin JK, Choi WJ, Lee JH, Paik WY

  • KMID: 2273006
  • Korean J Obstet Gynecol.
  • 2006 Dec;49(12):2631-2635.
Presacral teratomas are rare tumors derived from embryonic germ layers. They present mostly in infancy and are extremely rare in adults. Patient with presacral teratoma in adults may be asymptomatic...
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Recent Advances in Human Embryonic Stem Cell Research

Yoon HS, Yoo SJ, Lee JE, Lee JB, Kim SJ, Roh SI

The 21st century is considered as the era of Biotechnology (BT). Recently, the regenerative medicine using stem cells has been recognized as the future medicine, especially for the devastating diseases...
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