- Construction of an RNase P Ribozyme Library System for Functional Genomics Applications
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Hong SW, Choi HJ, Lee YH, Lee DK
- KMID: 2166248
- Genomics Inform.
- 2007 Mar;5(1):6-9.
An RNase P ribozyme library has been developed as a tool for functional genomics studies. Each clone of this library contains a random 18-mer and the sequence of M1 RNA,... -
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- ChroView: A Trace Viewer for Browsing and Editing Chromatogram files
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Tae HS, Kong EB, Park KJ
- KMID: 2166252
- Genomics Inform.
- 2007 Mar;5(1):30-31.
Many visualization tools have been designed to aid information processing during whole genome projects. We have developed a trace viewer program, ChroView, which can read a chromatogram file and display... -
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- Regression Models for Haplotype-Based Association Studies
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Oh SH, Namkung JH, Park TS
- KMID: 2166250
- Genomics Inform.
- 2007 Mar;5(1):19-23.
In this paper, we provide an overview of statistical models for haplotype-based association studies, and summarize their features based on the design matrix. We classify the design matrix into the... -
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- Evaluation of Advanced Structure-Based Virtual Screening Methods for Computer-Aided Drug Discovery
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Lee HS, Choi JW, Yoon SJ
- KMID: 2166251
- Genomics Inform.
- 2007 Mar;5(1):24-29.
Computational virtual screening has become an essential platform of drug discovery for the efficient identification of active candidates. Moleculardocking, a key technology of receptor-centric virtual screening, is commonly used to... -
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- An RNA Mapping Strategy to Identify Ribozyme-Accessible Sites on the Catalytic Subunit of Mouse Telomerase
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Song MS, Lee SW
- KMID: 2166253
- Genomics Inform.
- 2007 Mar;5(1):32-35.
Telomerase reverse transcriptase (TERT) is an enzymatic ribonucleoprotein that prolongs the replicative life span of cells by maintaining protective structures at the ends of eukaryotic chromosomes. Telomerase activity is highly... -
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- Detection of Neural Fates from Random Differentiation: Application of Support Vector MachineMin
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Lee MS, Ahn JH, Park WY
- KMID: 2166247
- Genomics Inform.
- 2007 Mar;5(1):1-5.
Embryonic stem cells can be differentiated into various types of cells, requiring a tight regulation of transcription. Biomarkers related to each lineage of cells are used to guide the differentiation... -
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- FCAnalyzer: A Functional Clustering Analysis Tool for Predicted Transcription Regulatory Elements and Gene Ontology Terms
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Kim SB, Ryu GM, Kim YJ, Heo JY, Park C, Oh BS, Kim HL, Kimm KC, Kim KW, Kim YY
- KMID: 2166249
- Genomics Inform.
- 2007 Mar;5(1):10-18.
Numerous studies have reported that genes with similar expression patterns are co-regulated. From gene expression data, we have assumed that genes having similar expression pattern would share similar transcription factor... -
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