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RepWeb: A Web-Based Search Tool for Repeat-Related Literatures

Woo T, Kim Y, Kwon J, Seo J

  • KMID: 2166261
  • Genomics Inform.
  • 2007 Jun;5(2):88-91.
Repetitive sequences such as SINE, LINE, and LTR elements form a major part of eukaryotic genomes. A literature search tool that summarizes the information contained within repeat elements would provide...
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Pharmacogenomics in Drug Discovery and Development

Ahn C

  • KMID: 2166254
  • Genomics Inform.
  • 2007 Jun;5(2):41-45.
Pharmacogenomics is the study that examines how genetic variations affect the ways in which people respond to drugs. The ways people respond to drugs are complex traits that are influenced...
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Molecular Imaging in the Age of Genomic Medicine

Byun J

  • KMID: 2166255
  • Genomics Inform.
  • 2007 Jun;5(2):46-55.
The convergence of molecular and genetic disciplines with non-invasive imaging technologies has provided an opportunity for earlier detection of disease processes which begin with molecular and cellular abnormalities. This emerging...
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Genetic Analysis of TGFA, MTHFR, and IFR6 in Korean Patients Affected by Nonsyndromic Cleft Lip with or without Cleft Palate (CL/P)

Park JY, Yoo HW, Kim Y

  • KMID: 2166256
  • Genomics Inform.
  • 2007 Jun;5(2):56-60.
Nonsyndromic cleft lip with or without cleft palate (CL/P) is a common craniofacial birth defect that is the result of a mixture of genetic and environmental factors. While studies have...
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A Statistical Analysis of SNPs, In-Dels, and Their Flanking Sequences in Human Genomic Regions

Shin SW, Kim YJ, Kim BD

  • KMID: 2166258
  • Genomics Inform.
  • 2007 Jun;5(2):68-76.
Due to the increasing interest in SNPs and mutational hot spots for disease traits, it is becoming more important to define and understand the relationship between SNPs and their flanking...
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Controlling Linkage Disequilibrium in Association Tests: Revisiting APOE Association in Alzheimer's Disease

Park L

  • KMID: 2166257
  • Genomics Inform.
  • 2007 Jun;5(2):61-67.
The allele frequencies of markers as well as linkage disequilibrium (LD) can be changed in cases due to the LD between markers and the disease allele, exhibiting spurious associations of...
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A DNA Microarray LIMS System for Integral Genomic Analysis of Multi-Platform Microarrays

Cho MK, Kang JJ, Park HS

  • KMID: 2166260
  • Genomics Inform.
  • 2007 Jun;5(2):83-87.
The analysis of DNA microarray data is a rapidly evolving area of bioinformatics, and various types of microarray are emerging as some of the most exciting technologies for use in...
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Serotonin (5-HT) Receptor Subtypes Mediate Regulation of Neuromodulin Secretion in Rat Hypothalamic Neurons

Chin C, Kim SI

  • KMID: 2166259
  • Genomics Inform.
  • 2007 Jun;5(2):77-82.
Serotonin (5-HT), the endogenous nonselective 5-HT receptor agonist, activates the inositol -1,4,5- triphosphate / calcium (InsP3/Ca2+) signaling pathway and exerts both stimulatory and inhibitory actions on cAMP production and neuromodulin...
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