- Genetic Hearing Loss and Gene Therapy
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Carpena NT, Lee MY
- KMID: 2439210
- Genomics Inform.
- 2018 Dec;16(4):e20.
- doi: 10.5808/GI.2018.16.4.e20
Genetic hearing loss crosses almost all the categories of hearing loss which includes the following: conductive, sensory, and neural; syndromic and nonsyndromic; congenital, progressive, and adult onset; high-frequency, low-frequency, or... -
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- Glaucoma, Stem Cells, and Gene Therapy: Where Are We Now?
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Daliri K, Ljubimov A, Hekmatimoghaddam S
- KMID: 2400866
- Int J Stem Cells.
- 2017 Nov;10(2):119-128.
- doi: 10.15283/ijsc17029
Glaucoma is the second most common cause of blindness, affecting 70~80 million people around the world. The death of retinal ganglion cells (RGCs) is the main cause of blindness related... -
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- Gene Therapy for Hearing Protection
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Lee MY
- KMID: 2386108
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2017 Jun;60(6):263-270.
- doi: 10.3342/kjorl-hns.2017.00514
Sensorineural hearing loss (SNHL) does not recover and only few exceptions exist. It is mostly due to the reason that hair cells in the cochlea cannot regenerate once damaged. Therefore,... -
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- Gene Therapy for Bone Tissue Engineering
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Kim YD, Pofali P, Park TE, Singh B, Cho K, Maharjan S, Dandekar P, Jain R, Choi YJ, Arote R, Cho CS
- KMID: 2360851
- Tissue Eng Regen Med.
- 2016 Apr;13(2):111-125.
- doi: 10.1007/s13770-016-9063-8
Gene therapy holds a great promise and has been extensively investigated to improve bone formation and regeneration therapies in bone tissue engineering. A variety of osteogenic genes can be delivered... -
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- Antitumor Effect of IP-10 by Using Two Different Approaches: Live Delivery System and Gene Therapy
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Taslimi Y, Zahedifard F, Habibzadeh S, Taheri T, Abbaspour , Sadeghipour A, Mohit E, Rafati S
- KMID: 2176319
- J Breast Cancer.
- 2016 Mar;19(1):34-44.
- doi: 10.4048/jbc.2016.19.1.34
PURPOSE: Immunotherapy is one of the treatment strategies for breast cancer, the most common cancer in women worldwide. In this approach, the patient's immune system is stimulated to attack microscopic... -
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- Microarray Analysis of Gene Expression Reveals that Cyclo-oxygenase-2 Gene Therapy Up-regulates Hematopoiesis and Down-regulates Inflammation During Endochondral Bone Fracture Healing
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Lau KH, Popa NL, Rundle CH
- KMID: 2286287
- J Bone Metab.
- 2014 Aug;21(3):169-188.
- doi: 10.11005/jbm.2014.21.3.169
BACKGROUND: Cyclo-oxygenase-2 (Cox-2) is an inflammatory mediator that is necessary for the tissue repair, including bone fracture healing. Although the application of Cox-2 gene therapy to a murine closed femoral... -
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- Spinal Fusion Based on Ex Vivo Gene Therapy Using Recombinant Human BMP Adenoviruses
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Kim GB, Kim JR, Ahn MH, Seo JS
- KMID: 2320138
- Yeungnam Univ J Med.
- 2007 Dec;24(2):262-274.
PURPOSE: Bone morphogenetic proteins (BMPs) play an important role in the formation of cartilage and bone, as well as regulating the growth of chondroblasts and osteoblasts. In this study, we... -
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- Development of Gene Therapy in the Inner Ear and Importance of Supporting Cells as Substrates
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Kim YH
- KMID: 2276799
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2007 Dec;50(12):1080-1086.
No abstract available. -
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- Comparison of Minicircle with Conventional Plasmid for the Non-viral Vascular Endothelial Growth Factor (VEGF) Gene Therapy
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Kwon M, Lee S, Chung H, Yoon C, Kim M, Park J
- KMID: 2177559
- J Korean Diabetes Assoc.
- 2007 Nov;31(6):465-471.
- doi: 10.4093/jkda.2007.31.6.465
BACKGROUND: Delayed wound healings in diabetic patients are related with the impairment of the expressions of various growth factors. Treatments using growth factors have been attempted on diabetic foot ulcer.... -
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- Gene therapy via adenovirus vector carrying matrix metalloproteinase-3 (MMP-3) in a rat model of liver cirrhosis
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Kim SY, Her WH, Ryu JS, Wang JS, Bae SH, Jang JW, Kim CW, Dong MS, Yoon SK
- KMID: 2256495
- Korean J Med.
- 2006 Dec;71(6):609-619.
BACKGROUND: Liver cirrhosis is characterized by fibrous scarring and hepatocellular regeneration. Matrix metalloproteinases (MMPs) comprise a family of zinc-dependent enzymes that degrade the extracellular matrix (ECM) components. This study examined... -
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- Combination of Gene Therapy with Antioxidant Therapy in a Rat Model of Vasculogenic Erectile Dysfunction
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Park K, Song SH, Kim SW, Paick JS
- KMID: 2226618
- Korean J Androl.
- 2006 Dec;24(3):150-155.
PURPOSE: To evaluate the combined effect of type 2 dimethylarginine dimethylaminohydrolase (DDAH) gene therapy with vitamin E treatment for the treatment of erectile dysfunction in atherosclerotic rats. Our previous study... -
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- Tumor targeted gene therapy
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Kang JH
- KMID: 1512522
- Nucl Med Mol Imaging.
- 2006 Oct;40(5):237-242.
Knowledge of molecular mechanisms governing malignant transformation brings new opportunities for therapeutic intervention against cancer using novel approaches. One of them is gene therapy based on the transfer of genetic... -
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- Gene Therapy for Erectile Dysfunction
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Ryu JK, Suh JK
- KMID: 2298605
- Korean J Androl.
- 2006 Aug;24(2):55-70.
It is now well known that vascular diseases, including hypercholesterolemia, atherosclerotic vascular disease, and diabetes mellitus are major causes for erectile dysfunction(ED). Despite the introduction of oral phosphodiesterase-5 inhibitors in... -
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- RANK-Fc Gene Therapy in Mouse Model of Osteoporosis
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Chung HY
- KMID: 2200730
- J Korean Soc Endocrinol.
- 2006 Jun;21(3):189-191.
- doi: 10.3803/jkes.2006.21.3.189
No abstract available. -
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- Monitoring Gene Therapy by Radionuclide Approaches
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Min JJ
- KMID: 2313019
- Nucl Med Mol Imaging.
- 2006 Apr;40(2):96-105.
Molecular imaging has its root in nuclear medicine and gene therapy monitoring. Therefore, recent progress in the development of non-invasive imaging technologies, particularly nuclear medicine, should allow molecular imaging to... -
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- Gene Therapy for Heart Failure
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Bae JW, Cho MC
- KMID: 2227138
- Korean Circ J.
- 2005 May;35(5):345-352.
- doi: 10.4070/kcj.2005.35.5.345
Heart failure is an important public medical problem in the developed countries. Although there are numerous and fascinating medicines given by physicians for the treatment of heart failure, the general... -
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- Gene Therapy for Diabetes Mellitus
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Park JH
- KMID: 2177772
- J Korean Diabetes Assoc.
- 2005 May;29(3):173-180.
No abstract available. -
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- The Effect of an AP-1 decoy on Collagen Synthesis in Wound Healing on Rat Skin: The use of Gene Therapy to Minimise Scarring
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Park SJ, Lee KS
- KMID: 2302636
- Korean J Dermatol.
- 2005 Apr;43(4):435-441.
BACKGROUND: The wound healing process is composed of inflammation, cellular growth, migration, angiogenesis and an extracellular matrix composition. In this process, fibroblasts proliferate but leave scarring due to their excessive... -
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- Construction of recombinant HSCC-1 adenovirus vector for oral cancer gene therapy
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Kim CH, Kim JW, Kim MJ, Pyo SW
- KMID: 2183811
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2005 Mar;27(2):103-109.
In spite of the ongoing advances, standard therapies for oral cancer still has some limitations in efficacy and in ability to prolong survival rate of advanced disease and result in... -
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- Adenovirus-mediated Gene Therapy of Uteroglobin Protects the Experimental Glomerulonephritis in Mice
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Kim HL, Yang SH, Sung EY, Lee JE, Lee DS, Chung JH, Kim YS
- KMID: 2079442
- Korean J Nephrol.
- 2005 Mar;24(2):181-190.
PURPOSE: Uteroglobin (UG), steroid inducible cytokine-like protein, has potent anti-inflammatory and immunomodulatory action. It is secreted by the mucosal epithelia of virtually all mammals. The aims of this study were... -
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