- Regulation of p53 Genes by Ferritin Light Chain: Preliminary Study
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Yi SY
- KMID: 1973943
- Ewha Med J.
- 2008 Jun;31(1):9-14.
- doi: 10.12771/emj.2008.31.1.9
No abstract available in English. -
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- The Clinical Significance of Mutation in the p53, DCC and nm23 Genes in Patients with Gastric Carcinoma
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Hwang SH, Oh SH, Choi YK
- KMID: 1599423
- Korean J Gastroenterol.
- 2001 Nov;38(5):325-335.
BACKGROUND/AIMS: Multiple gene abnormalities are observed in gastric carcinogenesis. We analyzed the mutation of p53, DCC and nm23 genes in gastric carcinoma and evaluated their clinical significance. METHODS: Mutations of p53,... -
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- Expression of p73 in Null-p53 SKOV3 Ovarian Cancer Cell Line
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Whang JD, Park CS, Choi JJ, Kim JS, Bae DS, Lee JH
- KMID: 2083732
- Korean J Gynecol Oncol Colposc.
- 1999 Jun;10(2):122-129.
p73, a first p53 relative, has been identified at chromosome 1p36, a region that is deleted in variety of human cancers. This protein shares strong homology with p53 protein, suggesting... -
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- Mutation of p53 and p16 Tumor Suppressor Genes in Cancer and Precancerous Lesions of the Gallbladder
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Yoon YB, Kim CY, Kim WH, Kim SW, Kim YT, Ryu JK, Lee WJ
- KMID: 2084961
- Korean J Gastroenterol.
- 1999 Sep;34(3):390-398.
BACKGROUND/AIMS: The purpose of this study was to analyze the frequencies of p53 and p16 gene mutations in gallbladder cancer and precancerous lesions such as dysplasia or adenoma. METHODS: Tissues... -
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- p53 Gene Mutations in Transitional Cell Carcinoma of the Renal Pelvis
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Uhm SY, Kong G, Park HY
- KMID: 1764378
- Korean J Urol.
- 1997 Apr;38(4):368-377.
Inactivation or loss of suppressor genes on a specific chromosome plays an important role in the development and progression of cancer. Recent studies have shown that p53 gene acts as... -
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- In Vitro Effect of Liposome-mediated Combined p16 and p53 Gene Transfer to the Human Glioblastoma Cell Lines
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Kim CH, Kwon JT, Min BK, Hwang SN, Hwang DY, Choi DY
- KMID: 1955924
- J Korean Neurosurg Soc.
- 2002 Feb;31(2):152-160.
OBJECTIVE: To overcome the limitations of the single gene transfer, the authors present the results of wild-type p16 and p53 combined genes transfer in vitro to the U251MG and U373MG... -
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- Oncogene interaction in basal cell carcinomas of human skin
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Ro YS
- KMID: 644859
- J Korean Med Sci.
- 1995 Apr;10(2):85-92.
- doi: 10.3346/jkms.1995.10.2.85
The expression of the p53 protein (p53) was compared with those of several oncogenes including c-fos (Fos), c-jun (Jun), and epidermal growth factor receptor (EGFR1) using immunohistochemistry in frozen and... -
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- bcl-2 and p53 Gene Expression in Colonic Adenoma and Carcinoma
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Lim CY, Kim JW, Song IH, Jin YJ, Rho IW, Park DK, Cho JH, Choi SB
- KMID: 2175437
- J Korean Cancer Assoc.
- 1998 Feb;30(1):89-99.
PURPOSE: Recently, it is suggested that the inhibitian of apoptosis is associated with tumorigenesis of colon. Bcl-2 gene is an important inhibitory regulator of apoptosis, and bcl-2 acts antagonistly with... -
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- Significance of p53 Protein Overexpression in Gallbladder Carcinoma
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Park YH, Kim WH, Kim SW, Han SU, Her KH
- KMID: 2128654
- Korean J Gastroenterol.
- 1998 Mar;31(3):366-376.
BACKGROUND AND AIMS: Mutation of the p53 tumor suppressor gene appears to be an important event in tumor development and progression. Overexpression of the p53 gene product has been widely... -
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- Effect of Adenovirus-p53 to Non-Small Cell Lung Cancer Cell Lines
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Park JH, Lee CT, Kim JH
- KMID: 2288947
- Korean J Thorac Cardiovasc Surg.
- 1998 Dec;31(12):1134-1146.
BACKGROUND: The tumor suppressor gene p53 is one of the most frequently altered genes in human tumors, including those of the lung. There is now a compelling evidence that wild-type... -
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- Expression of the mutant p53 gene in the carcinoma of the cervix uteri
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Kwon KI, Lee TS, Rhee JH, Cha SD, Lee SS, Suh YW
- KMID: 2245083
- Korean J Gynecol Oncol Colposc.
- 1994 Dec;5(4):23-28.
The nuclear accumulation of p53 protein is known to correspond with mutation of p53 tumor supressor gene. To investigate the relationsbip between clinico-pathologic features and expression of p53 mutations, 65... -
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- Patterns of p53 and H-ras Mutations related to Invasiveness and Differentiation of Transitional Cell Carcinoma in Human bladder
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Woo SH, Lee HL, Kim WJ
- KMID: 2290366
- Korean J Urol.
- 1999 Aug;40(8):963-970.
PURPOSE: To characterize the patterns of p53 & H-ras mutations related to invasiveness and differentiation of transitional cell carcinoma in human bladder. MATERIALS AND METHODS: Tissues from 52 patients diagnosed... -
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- Clinical Significance of p53 Gene Expression with Immunohistochemical Staining in Ovarian Cancer
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Kim JW, Lee YH, Kim YT, Lee CP, Kim DK, Song CH
- KMID: 1675641
- Korean J Gynecol Oncol Colposc.
- 1995 Mar;6(1):7-12.
Mutation of p53 gene is one of t.he commonest genetic changes in the development of human cancer including ovary. We intvestigated the diagnostic usefulness of the demonstration of p53 gene... -
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- Analysis of p53 Protein Overexpression in Invasive Cervical Cancer
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Kim JS, Kim SN, Sohn IS, Lee SK, Kim HG, Park TK
- KMID: 2075281
- Korean J Obstet Gynecol.
- 1997 Aug;40(8):1696-1701.
The p53 gene is a tumor suppressor gene and mutations in this gene play an import-ant role in the development of many human malignancies. The purpose of this study was... -
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- Gene Therapy of Brain Tumors:Effects of Adenovirus-mediated Wild Type p53 Gene Transfer in Human Glioma Cells
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Hong YK, Yung WK
- KMID: 2018899
- J Korean Neurosurg Soc.
- 1996 Aug;25(8):1561-1567.
The p53 tumor suppressor gene is one of the genes with greatest therapeutic potential for cancer treatment and its growth inhibitory mechanism is thought to be mediated through the activation... -
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- Distinct Mutation of p53 Gene in Bladder Cancer of Smoking and Nonsmoking Patients
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Shim HY, Heo YC, Cho YH
- KMID: 1563748
- Korean J Urol.
- 1998 Mar;39(3):247-250.
PURPOSE: It is well known that smoking is one of the most important etiologic factor in bladder cancer and mutations of p53 tumor suppressor gene are the important step... -
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- The Synergistic Cell Killing Effects by the Transduction of the w-p53 Gene and 5-FU Administration in Colon Cancer Cell Lines
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Kim HJ, Lee SC, Lee IK, Kang WK, Oh ST, Chang SK
- KMID: 2096476
- J Korean Surg Soc.
- 2007 Dec;73(6):481-489.
PURPOSE: It is known that the wild-type p53 (w-p53) gene has several functions such as suppression of tumor cell growth, control of the cell cycle, stabilization of the genes and... -
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- The Immunohistochemical Study on the Expression of p53 Tumor Suppressor Gene in the Gastric Adenocarcinoma
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Won YH, Lee OJ, Kim YC
- KMID: 1891132
- Korean J Gastroenterol.
- 1997 Jul;30(1):30-38.
BACKGROUND AND AIMS: Mutation and overexpression of the p53 gene have been noted in a wide range of human cancers and are thought to play a role in malignant transformation.... -
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- A Study of Apoptosis, and bcl-2 and p53 Expressions in Breast Cancer
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Kim DW, Jin SY, Lee DW
- KMID: 1906172
- J Korean Cancer Assoc.
- 1997 Jun;29(3):412-421.
PURPOSE: This study was undertaken for evaluation of the extent of apoptosis and expression of the bcl-2 gene and p53 gene as prognostic factors in breast cancer. MATERIALS AND METHODS:... -
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- The p53 Mutation and DNA Ploidy in Human Metastatic Breast Cancer
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Cho SJ, Kim AR, Won NH
- KMID: 1725216
- Korean J Pathol.
- 1997 Feb;31(2):135-144.
The p53 gene, one of the tumor suppressor genes, is believed to play an important role through mutation and overexpression in the progression of various human malignant tumors. To compare... -
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