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Mitochondrial Gene Therapy

Ko KS

Mitochondrial dysfunction contributes to a large variety of human disorders, ranging from neurodegenerative and neuromuscular diseases, obesity, and diabetes to ischemia-reperfusion injury and cancer. Increasing pharmacological efforts toward therapeutic interventions...
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The Frequency of Mitochondrial Gene Point Mutations in Korean Non-syndromic Sensorineural Hearing Loss

Jeong HS, Lim MJ, Chang SO, Kim CS, Oh SH

  • KMID: 2276112
  • Korean J Otolaryngol-Head Neck Surg.
  • 2004 Mar;47(3):206-211.
BACKGROUND AND OBJECTIVES: Mitochondrial point mutations have been shown to be responsible for syndromic and non-syndromic hearing impairment. Among these mitochondrial point mutations, 1555 A-->G, 3243 A-->G, and 7445 A-->G...
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