- Alterations in lung and gut microbiota reduce diversity in patients with nontuberculous mycobacterial pulmonary disease
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Choi JY, Shim B, Park Y, Kang YA
- KMID: 2547646
- Korean J Intern Med.
- 2023 Nov;38(6):879-892.
- doi: 10.3904/kjim.2023.097
Background/Aims: Although the incidence of nontuberculous mycobacteria pulmonary disease (NTM-PD), a chronic infectious disease, is increasing, lung and gut microbiota dysbiosis in NTM patients has rarely been studied and was... -
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- Human Immunodeficiency Virus Infection and Gut Microbiota: A Review on Gut Microbiome Associated with Immune Activation and Metabolic Diseases
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Joo EJ
- KMID: 2546478
- Korean J Med.
- 2023 Oct;98(5):208-211.
- doi: 10.3904/kjm.2023.98.5.208
This review provides the complex interaction between human immunodeficiency virus (HIV) infection and gut microbiota. HIV infection exerts chronic effects by impairing the immune system, closely linked with alterations in... -
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- Updates on ankylosing spondylitis: pathogenesis and therapeutic agents
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Kim SH, Lee SH
- KMID: 2546238
- J Rheum Dis.
- 2023 Oct;30(4):220-233.
- doi: 10.4078/jrd.2023.0041
Ankylosing spondylitis (AS) is an autoinflammatory disease that manifests with the unique feature of enthesitis. Gut microbiota, HLA-B*27, and biomechanical stress mutually influence and interact resulting in setting off a... -
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- Dissecting Causal Relationships Between Gut Microbiota, Blood Metabolites, and Stroke: A Mendelian Randomization Study
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Wang Q, Dai H, Hou T, Hou Y, Wang T, Lin H, Zhao Z, Li M, Zheng R, Wang S, Lu J, Xu Y, Liu R, Ning G, Wang W, Bi Y, Zheng J, Xu M
- KMID: 2546436
- J Stroke.
- 2023 Sep;25(3):350-360.
- doi: 10.5853/jos.2023.00381
Background and Purpose We investigated the causal relationships between the gut microbiota (GM), stroke, and potential metabolite mediators using Mendelian randomization (MR). Methods We leveraged the summary statistics of GM (n=18,340... -
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- Anti–PD-L1 Antibody and/or 17β-Estradiol Treatment Induces Changes in the Gut Microbiome in MC38 Colon Tumor Model
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Song CH, Kim N, Nam RH, Choi SI, Jang JY, Choi J, Lee HN
- KMID: 2544170
- Cancer Res Treat.
- 2023 Jul;55(3):894-909.
- doi: 10.4143/crt.2022.1427
Purpose 17β-Estradiol (E2) supplementation suppresses MC38 tumor growth by downregulating the expression of programmed death-ligand 1 (PD-L1). This study aims to figure out the gut microbiota that respond to anti–PD-L1... -
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- A Pilot Study Exploring Temporal Development of Gut Microbiome/ Metabolome in Breastfed Neonates during the First Week of Life
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Awan I, Schultz E, Sterrett JD, Dawud LM, Kessler LR, Schoch D, Lowry CA, Feldman-Winter L, Phadtare S
- KMID: 2540461
- Pediatr Gastroenterol Hepatol Nutr.
- 2023 Mar;26(2):99-115.
- doi: 10.5223/pghn.2023.26.2.99
Purpose: Exclusive breastfeeding promotes gut microbial compositions associated with lower rates of metabolic and autoimmune diseases. Its cessation is implicated in increased microbiome-metabolome discordance, suggesting a vulnerability to dietary changes. Formula... -
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- Diarrhea-predominant Irritable Bowel Syndrome-like Symptoms in Patients With Quiescent Crohn’s Disease: Comprehensive Analysis of Clinical Features and Intestinal Environment Including the Gut Microbiome, Organic Acids, and Intestinal Permeability
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Tomita T, Fukui H, Morishita D, Maeda A, Makizaki Y, Tanaka Y, Ohno H, Oshima T, Miwa H
- KMID: 2537945
- J Neurogastroenterol Motil.
- 2023 Jan;29(1):102-112.
- doi: 10.5056/jnm22027
Background/Aims Diarrhea-predominant irritable bowel syndrome (IBS-D)-like symptoms frequently occur in patients with quiescent Crohn’s disease (CD). To investigate the factors underlying IBS-D-like symptoms in patients with quiescent CD, we performed a... -
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- Changes in Gut Microbiome upon Orchiectomy and Testosterone Administration in AOM/DSS-Induced Colon Cancer Mouse Model
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Song CH, Kim N, Nam RH, Choi SI, Jang JY, Lee HN
- KMID: 2538005
- Cancer Res Treat.
- 2023 Jan;55(1):196-218.
- doi: 10.4143/crt.2022.080
Purpose Sex hormones are known to affect the gut microbiota. Previously, we reported that endogenous and exogenous testosterone are associated with colorectal cancer (CRC) development and submucosal invasion. In the... -
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- The Role of Short Chain Fatty Acids in Irritable Bowel Syndrome
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Jiang W, Wu J, Zhu S, Xin L, Yu C, Shen Z
- KMID: 2534313
- J Neurogastroenterol Motil.
- 2022 Oct;28(4):540-548.
- doi: 10.5056/jnm22093
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder that is characterized by abdominal pain and disordered bowel habits. The etiology of IBS is multifactorial, including abnormal gut-brain interactions, visceral... -
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- Enterochromaffin Cells–Gut Microbiota Crosstalk: Underpinning the Symptoms, Pathogenesis, and Pharmacotherapy in Disorders of Gut-Brain Interaction
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Wei L, Singh R, Ghoshal UC
- KMID: 2531182
- J Neurogastroenterol Motil.
- 2022 Jul;28(3):357-375.
- doi: 10.5056/jnm22008
Disorders of gut-brain interaction (DGBIs) are common conditions in community and clinical practice. As specialized enteroendocrine cells, enterochromaffin (EC) cells produce up to 95% of total body serotonin and coordinate... -
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- Gut Microbiota Alteration Influences Colorectal Cancer Metastasis to the Liver by Remodeling the Liver Immune Microenvironment
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Yuan N, Li X, Wang M, Zhang Z, Qiao L, Gao Y, Xu X, Zhi J, Li Y, Li Z, Jia Y
- KMID: 2531240
- Gut Liver.
- 2022 Jul;16(4):575-588.
- doi: 10.5009/gnl210177
Background/Aims:This study aimed to explore the effect of gut microbiota-regulated Kupffer cells (KCs) on colorectal cancer (CRC) liver metastasis. Methods: A series of in vivo and in vitro researches were showed... -
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- Firmicutes in Gut Microbiota Correlate with Blood Testosterone Levels in Elderly Men
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Matsushita M, Fujita K, Motooka D, Hatano K, Hata J, Nishimoto M, Banno E, Takezawa K, Fukuhara S, Kiuchi H, Pan Y, Takao T, Tsujimura A, Yachida S, Nakamura S, Obara W, Uemura H, Nonomura N
- KMID: 2530719
- World J Mens Health.
- 2022 Jul;40(3):517-525.
- doi: 10.5534/wjmh.210190
Purpose: In males, testosterone levels have been implicated in various diseases. Recently, the influence of gut microbialderived compounds on host metabolism has become evident, and it has been suggested that... -
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- Association between the Blautia/Bacteroides Ratio and Altered Body Mass Index after Bariatric Surgery
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Kim Y, Son D, Kim BK, Kim KH, Seo KW, Jung K, Park SJ, Lim S, Kim JH
- KMID: 2531391
- Endocrinol Metab.
- 2022 Jun;37(3):475-486.
- doi: 10.3803/EnM.2022.1481
Background: Current evidence support that the gut microbiota plays a potential role in obesity. Bariatric surgery can reduce excess weight and decrease the risk of life-threatening weight-related health problems and... -
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- Protocatechuic Acid, a Gut Bacterial Metabolite of Black Raspberries, Inhibits Adenoma Development and Alters Gut Microbiome Profiles in Apc Min/+ Mice
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Dong A, Lin CW, Echeveste CE, Huang YW, Oshima K, Yearsley M, Chen X, Yu J, Wang LS
- KMID: 2528091
- J Cancer Prev.
- 2022 Mar;27(1):50-57.
- doi: 10.15430/JCP.2022.27.1.50
Administration of black raspberries (BRBs) and their anthocyanin metabolites, including protocatechuic acid (PCA), has been demonstrated to exert chemopreventive effects against colorectal cancer through alteration of innate immune cell trafficking,... -
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- Distinct Gut Microbiota in Patients with Asymptomatic Hyperuricemia: A Potential Protector against Gout Development
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Kim HW, Yoon EJ, Jeong SH, Park MC
- KMID: 2526556
- Yonsei Med J.
- 2022 Mar;63(3):241-251.
- doi: 10.3349/ymj.2022.63.3.241
Purpose: Here, we aimed to elucidate the differences in microbiota composition between patients with gout and those with asymptomatic hyperuricemia (asHU) and determine the effect of uric acid-lowering therapy (ULT)... -
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- Gender-Specific Differences in Gut Microbiota Composition Associated with Microbial Metabolites for Patients with Acne Vulgaris
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Huang Y, Liu L, Chen L, Zhou L, Xiong X, Deng Y
- KMID: 2522131
- Ann Dermatol.
- 2021 Dec;33(6):531-540.
- doi: 10.5021/ad.2021.33.6.531
Background: The gut microbial dysbiosis and gender differences in the pathogenesis of acne vulgaris have long been postulated respectively. However, there was no data about a genderrelated discrepancy in gut... -
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- Proton Pump Inhibitor Use Increases Pyogenic Liver Abscess Risk: A Nationwide Cohort Study
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Oh JH, Kang D, Kang W, Guallar E, Cho J, Min YW
- KMID: 2521156
- J Neurogastroenterol Motil.
- 2021 Oct;27(4):555-564.
- doi: 10.5056/jnm20221
Background/Aims Proton pump inhibitors (PPIs) increase gastric pH and alter the gut microbiome. An increased risk for infectious diseases has been reported in PPI users. However, little is known about the... -
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- Brain to Belly: Abdominal Variants of Migraine and Functional Abdominal Pain Disorders Associated With Migraine
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LenglarT L, Caula C, Moulding T, Lyles A, Wohrer D, Titomanlio L
- KMID: 2521148
- J Neurogastroenterol Motil.
- 2021 Oct;27(4):482-494.
- doi: 10.5056/jnm20290
Migraine is one of the most frequent causes of primary headache and 9% of children suffer from migraines. Most children will continue to experience migraine attacks as adults, therefore it... -
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- Intestinal microbiota and inflammatory bowel diseases
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Eun CS
- KMID: 2520189
- J Korean Med Assoc.
- 2021 Sep;64(9):588-595.
- doi: 10.5124/jkma.2021.64.9.588
Background: The prevalence of inflammatory bowel diseases (IBD) has been rapidly increasing over the past several decades in Korea. IBD appears to be resulted from inappropriate and chronic activation of... -
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- Helicobacter pylori Eradication Therapy-associated Diarrhea
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Jo HG, Kim YS
- KMID: 2520224
- Korean J Helicobacter Up Gastrointest Res.
- 2021 Sep;21(3):203-214.
- doi: 10.7704/kjhugr.2021.0037
Eradication of Helicobacter pylori has contributed to the treatment of peptic ulcers and mucosa-associated lymphoid tissue lymphoma. Moreover, it has possibly decreased the prevalence of gastric cancer. However, eradication therapy... -
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