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Imbalance of Gut Streptococcus, Clostridium, and Akkermansia Determines the Natural Course of Atopic Dermatitis in Infant

Park YM, Lee SY, Kang MJ, Kim BS, Lee MJ, Jung SS, Yoon JS, Cho HJ, Lee E, Yang SI, Seo JH, Kim HB, Suh DI, Shin YH, Kim KW, Ahn K, Hong SJ

PURPOSE: The roles of gut microbiota on the natural course of atopic dermatitis (AD) are not yet fully understood. We investigated whether the composition and function of gut microbiota and...
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Architectural Changes in the Medial Gastrocnemius on Sonography after Nerve Ablation in Healthy Adults

Park JE, Seong YJ, Kim ES, Park D, Lee Y, Park H, Rha DW

Architectural changes in healthy muscle after denervation have not yet been reported. This study aimed to investigate architectural changes in the medial head of the gastrocnemius muscle (GCM) after aesthetic...
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A Multiplex Phytosterol Assay Utilizing Gas Chromatography-Mass Spectrometry for Diagnosis of Inherited Lipid Storage Disorders

Lee JH, Lee K, Jun SH, Song SH, Shin CH, Song J

No abstract available.
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Metabolic Profiling of Plasma from Pancreatic Cancer Patients in Korea

Gwon MR, Yoon YR, Seol YM, Choi YJ, Kim DU, Choe S, Lee SH, Hwang SY, Kim H

BACKGROUND/AIMS: Pancreatic cancer (PC) patients have poor prognoses because this cancer is typically diagnosed at an advanced stage and the therapeutic options are limited. We examined the potential of metabolic...
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Chemical Composition and Antimicrobial Efficiency of Swietenia macrophylla Seed Extract on Clinical Wound Pathogens

Gopalan HK, Md Hanafiah NF, Chean Ring L, Tan WN, Wahidin S, Hway TS, Yenn TW

Microbial wound infection prolonged the hospitalization and increase the cost for wound management. Silver is commonly used as antimicrobial wound dressing. However, it causes several adverse side effects. Hence, this...
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Comparison of volatile organic compounds between cigarette smoke condensate (CSC) and extract (CSE) samples

Kim YH, An YJ, Jo S, Lee SH, Lee SJ, Choi SJ, Lee K

Cigarette smoke is a major risk factor for several diseases, including chronic obstructive pulmonary and cardiovascular diseases. The toxicity of the cigarette smoke can be determined in vitro. The cytotoxicity...
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Chemical Composition and Antimicrobial Efficacy of Helminthostachys zeylanica against Foodborne Bacillus cereus

Yenn TW, Ring LC, Zahan KA, Abdul Rahman MS, Tan WN, Shaik Alaudin BJ

Helminthostachys zeylanica is a rare plant grows in lightly shaded areas. The fern was traditionally used as antipyretic and antiphlogistic agents. This study was aimed to evaluate the antibacterial potential...
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Sageretia thea fruit extracts rich in methyl linoleate and methyl linolenate downregulate melanogenesis via the Akt/GSK3β signaling pathway

Ko GA, Shrestha S, Kim Cho S

BACKGROUND/OBJECTIVES: Sageretia thea is traditionally used as a medicinal herb to treat various diseases, including skin disorders, in China and Korea. This study evaluated the inhibitory effect of Sageretia thea...
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Chemical Constituents of Essential Oils Possessing Anti-Influenza A/WS/33 Virus Activity

Choi HJ

OBJECTIVES: This study was conducted to determine whether essential oils had anti-influenza A/WS/33 virus activity and whether there were specific compounds associated with this activity. METHODS: There were 63 essential oils...
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Assessment of Hepatic Cytochrome P450 3A Activity Using Metabolic Markers in Patients with Renal Impairment

Kim AH, Yoon S, Lee Y, Lee J, Bae E, Lee H, Kim DK, Lee S, Yu KS, Jang IJ, Cho JY

BACKGROUND: The renal function of individuals is one of the reasons for the variations in therapeutic response to various drugs. Patients with renal impairment are often exposed to drug toxicity,...
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Antimicrobial Efficacy of Penicillium amestolkiae elv609 Extract Treated Cotton Fabric for Diabetic Wound Care

Rozman NA, Hamin NS, Ring LC, Nee TW, Mustapha M, Yenn TW

Diabetes mellitus is a chronic disorder which affects millions of population worldwide. Global estimates published in 2010 reported the world diabetic prevalence as 6.4%, affecting 285 million adults. Foot ulceration...
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Recent advances in biochemical and molecular analysis of congenital adrenal hyperplasia due to 21-hydroxylase deficiency

Choi JH, Kim GH, Yoo HW

The term congenital adrenal hyperplasia (CAH) covers a group of autosomal recessive disorders caused by defects in one of the steroidogenic enzymes involved in the synthesis of cortisol or aldosterone...
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Urinary concentration of 3-phenoxybenzoic acid in elementary students in South Korea

Jo HM, Ha M, Lee WJ

OBJECTIVES: Pyrethroid pesticides are among the most commonly using insecticides in South Korean households and have been the subject of considerable interest among public health professionals for their potential health...
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Scolicidal Effects of Black Cumin Seed (Nigella sativa) Essential Oil on Hydatid Cysts

Mahmoudvand H, Dezaki ES, Kheirandish F, Ezatpour B, Jahanbakhsh S, Harandi MF

Surgery remains the preferred treatment for hydatid cyst (cystic echinococcosis, CE). Various scolicidal agents have been used for inactivation of protoscolices during surgery, but most of them are associated with...
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Evaluation of the T-KB-H and 3-HB Kits for the Measurement of Serum Ketone and beta-Hydroxybutyric Acid

Lee K, Jun SH, Lee KW, Han M, Song SH, Park KU, Song J

  • KMID: 2312238
  • Lab Med Online.
  • 2014 Jan;4(1):22-27.
BACKGROUND: Diabetes mellitus and alcohol consumption are the most common causes of ketoacidosis in adults. Recently, beta-hydroxybutyric acid (betaHBA) was reported to be a potential serum biomarker in the diagnosis...
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GC/MS analysis of high-performance liquid chromatography fractions from Sophora flavescens and Torilis japonica extracts and their in vitro anti-neosporal effects on Neospora caninum

Seo HS, Kim KH, Kim DY, Park BK, Shin NS, Kim JH, Youn H

We analyzed alcoholic extracts of herbs possessing anti-neosporal activity against Neospora (N.) caninum. To identify the chemical components of Sophora (S.) flavescens and Torilis (T.) japonica associated with anti-neosporal activity,...
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Screening of functional components derived from fresh water laver, Prasiola japonica, and its pharmacological properties

Seo DW, Kim HJ, Jang SK, Jun M, Joo SS

  • KMID: 1498926
  • J Biomed Res.
  • 2013 Jun;14(2):83-90.
The aim of the current study was to analyze the active ingredients and to screen the pharmacological properties of freshwater laver, Prasiola japonica, the only species grown in Korea. According...
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Serum Concentration of Estradiol and Estrone Following Oral Administration of Low-dose Hormone Therapy in Postmenopausal Korean Women

Lee EJ, Lee BS, Kang BM, Yoon BK, Choi H, Kim JG, Park HM

  • KMID: 2201112
  • J Korean Soc Menopause.
  • 2011 Aug;17(2):75-80.
OBJECTIVES: To determine the baseline serum concentrations of estradiol and estrone in postmenopausal Korean women and the serum concentrations of estradiol and estrone after 4 and 16 weeks of treatment...
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Potential of Epicoccum purpurascens Strain 5615 AUMC as a Biocontrol Agent of Pythium irregulare Root Rot in Three Leguminous Plants

Koutb M, Ali EH

  • KMID: 2312592
  • Mycobiology.
  • 2010 Dec;38(4):286-294.
Epicoccum purpurascens stain 5615 AUMC was investigated for its biocontrol activity against root rot disease caused by Pythium irregulare. E. purpurascens greenhouse pathogenicity tests using three leguminous plants indicated that...
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Lotus (Nelumbo nuficera) flower essential oil increased melanogenesis in normal human melanocytes

Jeon S, Kim NH, Koo BS, Kim JY, Lee AY

In this study, the essential oil from lotus flower extract, including petals and stamens, was assessed with regard to its effects on melanogenesis in human melanocytes. The lotus flower essential...
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