- Treatment with low-energy shock wave alleviates pain in an animal model of uroplakin 3A-induced autoimmune interstitial cystitis/painful bladder syndrome
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Li H, Zhang Z, Peng J, Xin Z, Li M, Yang B, Fang D, Tang Y, Guo Y
- KMID: 2455963
- Investig Clin Urol.
- 2019 Sep;60(5):359-366.
- doi: 10.4111/icu.2019.60.5.359
PURPOSE: To investigate whether treatment with low-energy shock wave (LESW) alleviates pain and bladder dysfunction in a mouse model of uroplakin 3A (UPK3A)-induced interstitial cystitis/painful bladder syndrome (IC/PBS). MATERIALS AND METHODS:... -
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- Anti-inflammatory, Anti-arthritic and Analgesic Effect of the Herbal Extract Made from Bacopa monnieriis, Cassia fistula and Phyllanthus polyphyllus
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Yoon WH, Lee KH
- KMID: 2387060
- Nat Prod Sci.
- 2017 Jun;23(2):108-112.
- doi: 10.20307/nps.2017.23.2.108
Anti-inflammatory, anti-arthritic and analgesic activity of each herbal extract, which is extracted from Bacopa monnieriis, Cassia fistula and Phyllanthus polyphyllus, respectively. The treatment of herbal extract exhibited anti-inflammatory effect as... -
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- Antinociceptive Effects of Prim-O-Glucosylcimifugin in Inflammatory Nociception via Reducing Spinal COX-2
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Wu LQ, Li Y, Li YY, Xu SH, Yang ZY, Lin Z, Li J
- KMID: 2351691
- Biomol Ther.
- 2016 Jul;24(4):418-425.
- doi: 10.4062/biomolther.2015.168
We measured anti-nociceptive activity of prim-o-glucosylcimifugin (POG), a molecule from Saposhnikovia divaricate (Turcz) Schischk. Anti-nociceptive or anti-inflammatory effects of POG on a formalin-induced tonic nociceptive response and a complete Freund's... -
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- Differential Role of Central GABA Receptors in Nociception of Orofacial Area in Rats
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Lee AR, Lim NH, Kim HJ, Kim MJ, Ju JS, Park MK, Lee MK, Yang KY, Ahn DK
- KMID: 2068541
- Int J Oral Biol.
- 2015 Sep;40(3):117-125.
- doi: 10.11620/IJOB.2015.40.3.117
The present study investigated the role of central GABA(A) and GABA(B) receptors in orofacial pain in rats. Experiments were conducted on Sprague-Dawley rats weighing between 230 and 280 g. Intracisternal... -
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- Antinociceptive Effects of Transcytosed Botulinum Neurotoxin Type A on Trigeminal Nociception in Rats
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Kim HJ, Lee GW, Kim MJ, Yang KY, Kim ST, Bae YC, Ahn DK
- KMID: 2285578
- Korean J Physiol Pharmacol.
- 2015 Jul;19(4):349-355.
- doi: 10.4196/kjpp.2015.19.4.349
We examined the effects of peripherally or centrally administered botulinum neurotoxin type A (BoNT-A) on orofacial inflammatory pain to evaluate the antinociceptive effect of BoNT-A and its underlying mechanisms. The... -
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- Botulinum Toxin Type A Attenuates Activation of Glial Cells in Rat Medullary Dorsal Horn with CFA-induced Inflammatory Pain
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Kim MJ, Cho JH, Kim HJ, Yang KY, Ju JS, Lee MK, Park MK, Ahn DK
- KMID: 1827455
- Int J Oral Biol.
- 2015 Jun;40(2):71-77.
- doi: 10.11620/IJOB.2015.40.2.071
The activation of glial cells in the spinal cord has been contribute to the initiation and maintenance of pain facilitation induced by peripheral inflammation and nerve injury. The present study... -
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- Infliximab Partially Alleviates the Bite Force Reduction in a Mouse Model of Temporomandibular Joint Pain
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Kim SH, Son CN, Lee HJ, Cho HC, Jung SW, Hur JA, Baek WK, Jung HR, Hong JH
- KMID: 2155467
- J Korean Med Sci.
- 2015 May;30(5):552-558.
- doi: 10.3346/jkms.2015.30.5.552
Temporomandibular joint (TMJ) disorder is clinically important because of its prevalence, chronicity, and therapy-refractoriness of the pain. In this study, we investigated the effect of infliximab in a mouse model... -
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- Principles and Application of Mouse Model of Allergic Rhinitis
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Mo JH
- KMID: 2277831
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2015 Mar;58(3):159-165.
- doi: 10.3342/kjorl-hns.2015.58.3.159
Allergic rhinitis is a one of the most prevalent disease and its prevalence has been increasing these days. Many researchers have used the mouse models to study the mechanism of... -
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- Involvement of Endoplasmic Reticulum Stress Response in Orofacial Inflammatory Pain
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Yang ES, Bae JY, Kim TH, Kim YS, Suk K, Bae YC
- KMID: 2165542
- Exp Neurobiol.
- 2014 Dec;23(4):372-380.
- doi: 10.5607/en.2014.23.4.372
Endoplasmic reticulum (ER) stress is involved in many neurological diseases and inflammatory responses. Inflammatory mediators induce neuronal damage and trigger the neuropathic or inflammatory pain. But there is very little... -
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- Participation of Central P2X7 Receptors in CFA-induced Inflammatory Pain in the Orofacial Area of Rats
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Yang KY, Kim MD, Ju JS, Kim MJ, Ahn DK
- KMID: 1703491
- Int J Oral Biol.
- 2014 Mar;39(1):49-56.
We investigated the role of central P2X receptors in inflammatory pain transmission in the orofacial area in rats. Experiments were carried out using male Sprague-Dawley rats weighing 230-280g. Complete Freund's... -
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- Influence of the Adjuvants and Genetic Background on the Asthma Model Using Recombinant Der f 2 in Mice
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Chang YS, Kim YK, Jeon SG, Kim SH, Kim SS, Park HW, Min KU, Kim YY, Cho SH
- KMID: 2150791
- Immune Netw.
- 2013 Dec;13(6):295-300.
- doi: 10.4110/in.2013.13.6.295
Der f 2 is the group 2 major allergen of a house dust mite (Dermatophagoides farinae) and its function has been recently suggested. To determine the optimal condition of sensitization... -
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- Anti-inflammatory Effect of Isaria sinclairii Glycosaminoglycan in an Adjuvant-treated Arthritis Rat Model
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Ahn MY, Jee SD, Hwang JS, Yun EY, Ahn KS, Kim YS
- KMID: 2317835
- Toxicol Res.
- 2013 Sep;29(3):195-201.
The anti-inflammatory effects of glycosaminoglycan (GAG) derived from Isaria sinclairii (IS) and of IS extracts were investigated in a complete Freund's adjuvant (CFA)-treated chronic arthritis rat model. Groups of rats... -
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- Participation of Peripheral P2X Receptors in Orofacial Inflammatory Nociception in Rats
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Park MK, Song HC, Yang KY, Ju JS, Ahn DK
- KMID: 2170745
- Int J Oral Biol.
- 2011 Sep;36(3):143-148.
The present study investigated the role of peripheral P2X receptors in inflammatory pain transmission in the orofacial area in rats. Experiments were carried out on male Sprague-Dawley rats weighing 220... -
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- A Blockade of the Central MAPK Pathway Attenuates Referred Pain in Rats with Complete Freund's Adjuvant-Induced Inflammation of the Temporomandibular Joint
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Won KA, Lim NH, Lee MK, Park MK, Yang GY, Park YY, Ahn DK, Bae YC
- KMID: 1457180
- Int J Oral Biol.
- 2010 Sep;35(3):83-89.
We investigated the role of the central MAPK pathways in extra-territorial (referred) pain resulting from inflammation of the temporomandibular joint (TMJ). Experiments were carried out on male Sprague-Dawley rats weighing... -
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- The Role of Central Group I mGluRs for CFA-induced Knee Joint Pain Model in Rats
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Han MA, Chang SH
- KMID: 2236601
- Korean J Anesthesiol.
- 2007 Oct;53(4):504-512.
- doi: 10.4097/kjae.2007.53.4.504
BACKGROUND: Glutamate is the predominant excitatory neurotransmitter in the central and peripheral nervous system and has known to be involved in nociceptive transmission and central sensitization. It acts through ligand... -
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- Changes in Acetylcholine Receptors and Functional Characterization in Muscle by TOF Stimulation in Rat Experimental Autoimmune Myasthenia Gravis (EAMG) Model
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Chon JY, Lee HJ
- KMID: 1937596
- Korean J Anesthesiol.
- 2007 Mar;52(3):310-317.
- doi: 10.4097/kjae.2007.52.3.310
BACKGROUND: The aim of study is to investigate the initial functional changes of muscle in rats induced to have myasthenia gravis, experimental autoimmune myasthenia gravis (EAMG). The authors investigated the... -
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- Effects of Electroacupuncture on the Expression of Spinal Neuronal Nitric Oxide Synthase in Adjuvant-induced Arthritic Rat Model
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Ryu JW, Gil YG, Choi BT
- KMID: 1583641
- Korean J Phys Anthropol.
- 2006 Sep;19(3):215-222.
To examine the effects of electroacupuncture (EA) on central nociceptive modulation, expressional changes of spinal neuronal nitric oxide synthase (nNOS) were investigated in complete Freund's adjuvant (CFA)-injected rats. Inflammation was induced by... -
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- Vitamin E Reduces Symptoms in a CFA-induced Model of Monoarthritis
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Lee KC, Moon KH, Kim DK, Lee KS, Woo NS, Lee YC
- KMID: 1862266
- Korean J Anesthesiol.
- 2006 Jun;50(6):S61-S67.
- doi: 10.4097/kjae.2006.50.6.S61
BACKGROUND: Adjuvant arthritic animals show immunologic and inflammatory features which are also observed in patients with rheumatoid arthritis. This study investigated whether high dose vitamin E (alpha-tocopherol) has any additional... -
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- Alteration of Ionic Zinc Distribution in Rat Spinal Ganglion by Inflammatory Pain Stimulus: Autometallography
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Lee B, Jun G, Kim YS, Lee B, Lee YI, Kim DJ, Jo SM
- KMID: 2224492
- Korean J Anat.
- 2005 Dec;38(6):561-566.
This study was designed to investigate any correlation between the mechanism of pain development and changes of histochemically reactive zinc contents in the rat spinal ganglion following complete Freund's Adjuvant... -
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- Dermatophagoides Farinae-Induced Asthmatic Mouse Model of Airway Remodeling
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- KMID: 2299724
- Korean J Asthma Allergy Clin Immunol.
- 2004 Sep;24(3):310-317.
BACKGROUND: Although murine models have been useful in understanding acute airway inflammation in asthma, the ovalbumin induced murine models of asthma have significant limitations in study of airway remodeling. OBJECTIVE: We... -
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