- Oxytocin Levels in Children with Separation Anxiety and Their Mothers before and after Treatment
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Üstün NSG, Gümüş , Soylu N
- KMID: 2545810
- Clin Psychopharmacol Neurosci.
- 2023 Aug;21(3):499-515.
- doi: 10.9758/cpn.22.1008
Objective: The purpose of this study was to compare the plasma oxytocin levels of children with separation anxiety disorder (SAD) and their mothers with those of healthy controls and to... -
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- Boophone disticha attenuates five day repeated forced swim-induced stress and adult hippocampal neurogenesis impairment in male Balb/c mice
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Khuthazelani Xhakaza N, Nkomozepi P, Mbajiorgu EF
- KMID: 2540987
- Anat Cell Biol.
- 2023 Mar;56(1):69-85.
- doi: 10.5115/acb.22.120
Depression is one of the most common neuropsychiatric disorders and is associated with dysfunction of the neuroendocrine system and alterations in specific brain proteins. Boophone disticha (BD) is an indigenous... -
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- Atomoxetine and Fluoxetine Activate AMPK-ACC-CPT1 Pathway in Human SH-SY5Y and U-87 MG Cells
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Jeon S, Park JE, Do YH, Santos R, Lee SM, Kim BN, Cheong JH, Kim Y
- KMID: 2540696
- Psychiatry Investig.
- 2023 Mar;20(3):212-219.
- doi: 10.30773/pi.2022.0255
Objective Atomoxetine and fluoxetine are psychopharmacologic agents associated with loss of appetite and weight. Adenosine monophosphate-activated protein kinase (AMPK) is the cellular energy sensor that regulate metabolism and energy, being... -
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- Fluoxetine affects cytosolic cAMP, ATP, Ca2+ responses to forskolin, and survival of human ovarian granulosa tumor COV434 cells
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Nguyen TMD, Klett D, Combarnous Y
- KMID: 2514944
- Korean J Physiol Pharmacol.
- 2021 May;25(3):189-195.
- doi: 10.4196/kjpp.2021.25.3.189
Fluoxetine (FLX), a selective serotonin reuptake inhibitor antidepressant, exhibits various other mechanisms of action in numerous cell types and has been shown to induce cell death in cancer cells, paving... -
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- Changes in the levels of comet parameters before and after fluoxetine therapy in major depression patients
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Panwar R, Sivakumar M, Menon V, Vairappan B
- KMID: 2503449
- Anat Cell Biol.
- 2020 Jun;53(2):194-200.
- doi: 10.5115/acb.19.217
Major depression belongs to mood disorders and characterized by worthlessness, no interest or happiness in any activity; lasting for atleast two weeks. Etio-pathological changes of major depression include oxidative stress... -
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- Fluoxetine Simultaneously Induces Both Apoptosis and Autophagy in Human Gastric Adenocarcinoma Cells
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Po WW, Thein W, Khin PP, Khing TM, Han KWW, Park CH, Sohn UD
- KMID: 2507833
- Biomol Ther.
- 2020 Mar;28(2):202-210.
- doi: 10.4062/biomolther.2019.103
Fluoxetine is used widely as an antidepressant for the treatment of cancer-related depression, but has been reported to also have anti-cancer activity. In this study, we investigated the cytotoxicity of... -
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- Fluoxetine Induces Apoptotic and Oxidative Neuronal Death Associated with The Influx of Copper Ions in Cultured Neuronal Cells
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Hwang S, Kim JK
- KMID: 2468142
- Chonnam Med J.
- 2020 Jan;56(1):20-26.
- doi: 10.4068/cmj.2020.56.1.20
We examined the effect of fluoxetine, a selective serotonin reuptake inhibitor antidepressant, on neuronal viability in mouse cortical near-pure neuronal cultures. Addition of fluoxetine to the media for 24 hours... -
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- Emerging Hyperprolactinemic Galactorrhea in Obsessive Compulsive Disorder with a Stable Dose of Fluoxetine
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Chatterjee SS, Mitra S, Mallik N
- KMID: 2171035
- Clin Psychopharmacol Neurosci.
- 2015 Dec;13(3):316-318.
- doi: 10.9758/cpn.2015.13.3.316
While fluoxetine (FXT) is a frequently prescribed selective serotonin reuptake inhibitor (SSRI), with few major side-effects; altered serotonergic transmissions in hypothalamic pathways might lead to a distressing, and often embarrassing,... -
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- Effects of Clozapine, Haloperidol, and Fluoxetine on the Reversal of Cocaine-Induced Locomotor Sensitization
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Cha SK, Kang UG
- KMID: 2316373
- Psychiatry Investig.
- 2014 Oct;11(4):454-458.
- doi: 10.4306/pi.2014.11.4.454
OBJECTIVE: Repeated treatment with psychostimulants induces sensitization of the dopaminergic system in the brain. Dopaminergic sensitization has been proposed as a mechanism of psychosis. Although antipsychotics block the expression of... -
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- Dehydroevodiamine.HCl Improves Stress-Induced Memory Impairments and Depression Like Behavior in Rats
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Kim HJ, Shin KY, Chang KA, Ahn S, Choi HS, Kim HS, Suh YH
- KMID: 2285491
- Korean J Physiol Pharmacol.
- 2014 Feb;18(1):55-59.
- doi: 10.4196/kjpp.2014.18.1.55
Dehydroevodiamine.HCl (DHED) has been reported to prevent memory impairment and neuronal cell loss in a rat model with cognitive disturbance. We investigated the effect of DHED on memory impairment and... -
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- Fluoxetine Increases the Expression of NCAM140 and pCREB in Rat C6 Glioma Cells
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Choi MR, Oh DH, Kim SH, Jung KH, Das ND, Chai YG
- KMID: 2316180
- Psychiatry Investig.
- 2012 Jun;9(2):180-186.
OBJECTIVE: Dysfunction of neural plasticity in the brain is known to alter neural networks, resulting in depression. To understand how fluoxetine regulates molecules involved in neural plasticity, the expression levels... -
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- A Case of Serotonin Syndrome Induced by Fluoxetine and Duloxetine Independently in a Same Patient
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You S, Noh JS
- KMID: 2287474
- Korean J Psychopharmacol.
- 2012 Apr;23(2):74-77.
Here we report a case of serotonin syndrome caused by fluoxetine 20 mg and duloxetine 60 mg independently eight week apart. A 65-year old man developed fever, agitation and change... -
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- Fluoxetine Up-Regulates Bcl-xL Expression in Rat C6 Glioma Cells
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Choi MR, Oh DH, Kim SH, Yang BH, Lee JS, Choi J, Jeon HS, Chai YG, Park YC
- KMID: 2316048
- Psychiatry Investig.
- 2011 Jun;8(2):161-168.
OBJECTIVE: To analyze both differentially expressed genes and the Bcl-xL protein expression after acute and chronic treatment with fluoxetine in rat C6 glioma cells. METHODS: C6 glioma cells were cultured for... -
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- A Data Warehouse Based Retrospective Post-marketing Surveillance Method: A Feasibility Test with Fluoxetine
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Park MY, Lee YH, Kim EY, Kim WJ, Kam HJ, Choi JP, Han TH, Kang UG, Park RW
- KMID: 2211388
- J Korean Soc Med Inform.
- 2009 Jun;15(2):191-199.
- doi: 10.4258/jksmi.2009.15.2.191
OBJECTIVE: Post-marketing surveillance (PMS) is an adverse events monitoring practice of pharmaceutical drugs on the market. Traditional PMS methods are labor intensive and expensive to perform, because they are largely... -
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- Chronic Treatment of Fluoxetine Increases Expression of NCAM140 in the Rat Hippocampus
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Choi MR, Chai YG, Jung KH, Baik SY, Kim SH, Roh S, Choi J, Lee JS, Choi IG, Yang BH
- KMID: 2249447
- Korean J Biol Psychiatry.
- 2009 Feb;16(1):5-14.
OBJECTIVES: Most of the mechanisms reported for antidepressant drugs are the enhancement of neurite outgrowth and neuronal survival in the rat hippocampus. Neural cell adhesion molecule 140(NCAM140) has been implicated... -
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- Pharmacological Therapy of Prozac
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Lyoo IK, Lee JY, Lee JH
- KMID: 2394804
- J Korean Med Assoc.
- 2008 Mar;51(3):273-282.
Fluoxetine (Prozac(R)) has been reported to have equivalent efficacy and less side effects compared to the tricyclic antidepressants. It has become a new trend in the treatment of major depressive... -
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- Factors Associated With the Response to Fluoxetine Treatment in Child and Adolescent Patients with Major Depressive Disorder; A Naturalistic Study
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Jung YE, Moon HJ, Seo HJ, Bahk WM, Jun TY, Chae JH
- KMID: 2287432
- Korean J Psychopharmacol.
- 2008 Mar;19(2):94-100.
OBJECTIVE: We evaluated the overall efficacy of fluoxetine and explored factors associated with the response to fluoxetine treatment in child and adolescent outpatients with major depression. METHODS: Child and adolescent outpatients... -
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- A Case of Fluoxetine Induced Mania in Poststroke Depression Patient: A case report
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Cho YR, Kim HW, Lee JI, Yun JS, Lee JS, Woo YS
- KMID: 2136473
- J Korean Acad Rehabil Med.
- 2008 Feb;32(1):116-118.
Poststroke depression is very common and has been reported in as many as 40~50% of poststroke patients. The fluoxetine is one of the most frequently prescribed drugs for the treatment... -
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- The Effect of Fluoxetine on Behaviors in Transient Forebrain Ischemic Gerbil
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Li H, Kim DH, Won MH, Yan JJ
- KMID: 854048
- Korean J Psychopharmacol.
- 2006 Nov;17(6):565-572.
OBJECTIVE: This study aims to explore the effect of fluoxetine on memory, locomotor and depressive behavior in transient forebrain ischemic model of gerbil. METHODS: Doses of fluoxetine (10, 40 mg/kg)... -
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- Vaginal Bleeding Associated with Venlafaxine Add-On Therapy: A Case Report
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Jon DI
- KMID: 2287246
- Korean J Psychopharmacol.
- 2006 Mar;17(2):238-240.
Venlafaxine is often considered to be safer than established antidepressants except the risk of hypertension. In terms of vaginal bleeding associated with venlafaxine, only one case has been reported. The... -
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