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Fetal therapies as standard prenatal care in Japan

Sago H, Wada S

With recent advances in fetal medicine, various attempts have been made to save fetuses facing perinatal death or devastating consequences despite optimal management after birth. The concept of the fetus...
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Sirolimus therapy for fetal cardiac rhabdomyoma in a pregnant woman with tuberous sclerosis

Park H, Chang CS, Choi SJ, Oh SY, Roh CR

Rhabdomyoma is the most common fetal cardiac tumor, and its development is related to tuberous sclerosis. Fetal cardiac rhabdomyomas often spontaneously regress in utero or after birth, but large tumors...
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Ex utero intrapartum treatment procedure in two fetuses with airway obstruction

Lee J, Lee MY, Kim Y, Shim JY, Won HS, Jeong E, Lee BS, Kim KS, Choi WJ, Lee YS

The ex utero intrapartum treatment (EXIT) procedure was introduced to reduce fetal hypoxic damage while establishing an airway in fetuses with upper and lower airway obstruction. Delivery of the fetal...
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Use of Stem Cell in Fetal Therapy: Current Status and Future Perspectives

Lee SW

During the past decades, there has been a great evolution in the field of fetal therapy for congenital defects. Prenatal screening or diagnostic methods including non-invasive and invasive methods and...
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First reported case of fetal aortic valvuloplasty in Asia

Yoon SY, Won HS, Lee MY, Cho MK, Jung E, Kim KS, Kim YH

Prenatal intervention of severe fetal aortic valve stenosis by ultrasound-guided percutaneous balloon valvuloplasty has been performed to prevent the progression to hypoplastic left heart syndrome, and achieve biventricular circulation in...
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Intrauterine therapy for macrocystic congenital cystic adenomatoid malformation of the lung

Min JY, Won HS, Lee MY, Suk HJ, Shim JY, Lee PR, Kim A

  • KMID: 2313992
  • Obstet Gynecol Sci.
  • 2014 Mar;57(2):102-108.
OBJECTIVE: To report on our experiences with thoracoamniotic shunting and/or the injection of a sclerosing agent (OK-432) to treat fetuses diagnosed with macrocystic congenital cystic adenomatoid malformation (CCAM) of the...
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An unusual prenatal manifestation of a huge congenital cystic adenomatoid malformation with favorable perinatal outcome

Suk HJ, Won HS, Lee EJ, Lee MY

  • KMID: 2313986
  • Obstet Gynecol Sci.
  • 2014 Jan;57(1):73-76.
Congenital cystic adenomatoid malformation (CCAM) is a rare condition which is easily detectable by prenatal ultrasonography. Fetuses with large CCAMs associating with hydrops are predisposed to perinatal mortality, therefore prenatal...
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Perinatal outcome of twin reversed arterial perfusion sequence: A single center's experience

Lee MY, Won HS, Lee KA, Kyeong KS, Jeon EJ, Shim JY, Lee PR, Kim A

OBJECTIVE: To report our experience of using radiofrequency ablation (RFA) to treat fetuses diagnosed with twin reversed arterial perfusion (TRAP) sequence and to evaluate the perinatal outcome of pump twins. METHODS:...
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The Present of Fetal Therapy and Future Prospect

Ko HS, Shin JC

  • KMID: 2280818
  • Korean J Perinatol.
  • 2011 Jun;22(2):95-107.
Advances in prenatal diagnosis have led to the prenatal management of a variety of congenital diseases. Fetal surgery was born of clinical necessity. Observations by pediatric surgeons and neonatologists of...
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The clinical outcomes on fetal gastroschisis

Cha KH, Park SK, Hyun MK, Na SH, Kim EG, Shim JY, Won HS, Lee PR, Kim A

  • KMID: 2273778
  • Korean J Obstet Gynecol.
  • 2009 Oct;52(10):994-999.
OBJECTIVE: The aim of this study is to analyze the perinatal courses, fetal treatment and postnatal outcomes of fetal gastroschisis. METHODS: A retrospective review of the medical records of 35 cases...
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Successful antenatal treatment of early fetal chylothorax with OK-432 pleurodesis

Yim GW, Kwon JY, Park YW, Kim YH

  • KMID: 2273744
  • Korean J Obstet Gynecol.
  • 2009 Jul;52(7):752-758.
Fetal chylothorax is a rare congenital manifestation that shows variable clinical outcome ranging from complete spontaneous resolution to progression into hydrops or lung hypoplasia. There is no consensus in the...
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Fetal Therapy

Chung IB

  • KMID: 2272814
  • Korean J Obstet Gynecol.
  • 2006 Apr;49(4):741-749.
Since fetal therapy is a newly developed field as a pioneer during the last few decades, initial activity before the year 2002 was based on successful case reports and case...
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Fetal pulmonary sequestration complicated hydrops: Successful fetal therapy by thoracoamniotic shunting

Kang EJ, Park MH, Hur SE, Kim YJ, Ahn JJ, Kim JI, Chun SH

  • KMID: 2272742
  • Korean J Obstet Gynecol.
  • 2005 Nov;48(11):2687-2693.
Pulmonary sequestration is development mass of nonfunctioning bronchopulmonary tissue that is separate from the normal tracheobroncheal tree and receives arterial blood from the systemic circulation. Pulmonary sequestration has an excellent...
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Three cases of Twin-to-Twin Transfusion Syndrome which were managed with maternal digitalization

Song GA, Choi IJ, Jun HJ, Lee YA, Cha MS, Je GH

  • KMID: 2272447
  • Korean J Obstet Gynecol.
  • 2004 Nov;47(11):2217-2223.
Twin-to-twin transfusion syndrome (TTTS) is one of the complications showing high mortality rate in monochorionic twins with vascular communication in the placenta. Clinical manifestations of TTTS are usually characterized by...
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A Case of Fetal Supraventricular Tachycardia with Fetal Ascites Treated by Antiarrhythmic Agent

Shin BS, Cho Y, Ro ES, Lee DO, Mun KS

  • KMID: 2077164
  • Korean J Obstet Gynecol.
  • 2004 Sep;47(9):1794-1799.
We experienced a case of fetal supraventricular tachycardia (SVT) with fetal ascites diagnosed at 29 weeks of gestation in 29 year-old primigravida woman. Transplacental fetal therapy with maternal oral antiarrhythmic...
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Cordocentesis for prenatal diagnosis and therapy: experience of 461 cases

Oh JY, Won HS, Kim SR, Koo BS, Kim JS, Chung JY, Lee PR, Kim A

  • KMID: 2076744
  • Korean J Obstet Gynecol.
  • 2002 Nov;45(11):1996-2000.
OBJECTIVE: We report our experience with cordocentesis for prenatal diagnosis and therapy. The clinical effect and safety of cordocentesis were evaluated. MATERIALS AND METHODS: From June 1997 to December 2001,...
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A Case of Fetal Erythroblastosis Treated by Repeated Intraumbilical Venous Transfusions

Kwon YS, Won HS, Kim SR, Chung JY, Lee PR, Lee IS, Kim A

  • KMID: 2262495
  • Korean J Obstet Gynecol.
  • 2001 Dec;44(12):2339-2343.
Fetal erythroblastosis caused by maternal Rhesus alloimmunization brings a significant clinical problem, eventually leading to fetal hydrops and intrauterine fetal death. Repeated blood transfusions into the umbilical vein are the...
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In-utero fetal therapy of posterior urethral valve syndrome: A case of vesicoamniotic shunting using a basket-shaped catheter

Cha JM, Won HS, Kim MK, Kim SR, Chung JY, Lee PR, Lee IS, Kim A

  • KMID: 2270109
  • Korean J Obstet Gynecol.
  • 2001 Feb;44(2):400-404.
We present a case of in-utero treatment of posterior urethral valve syndrome(PUVS) by vesicoamniotic shunting. The shunt was established by basket-shaped catheter at the 22 weeks' gestation. Enlarged bladder and...
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The fetal therapy of congenital cystic adenomatoid malformation of the lung in - utero : Two cases of thoracoamniotic shunting using a basket - shaped catheter

Chung JY, Won HS, Kim SR, Seo MD, Bo CH, Kim HK, Lee PR, Lee IS, Kim A

  • KMID: 1569695
  • Korean J Obstet Gynecol.
  • 2000 Oct;43(10):1894-1899.
No abstract available.
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A Case of Fetal Atrial Flutter Treated by Antiarrhythmic Agent to the Mother

Lee JY, Kim EM, Song TB, Han S, Kim YH, Ma JS

  • KMID: 2261383
  • Korean J Obstet Gynecol.
  • 1999 Mar;42(3):660-663.
The incidence of fetal cardiac arrhythmia is approximately 1-3%. Sustatined fetal tachyarrhythmia may cause fetal hydrops and rnay lead to fetal death. We experienced a case of fetal atrial flutter...
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