- Nutrient intakes and medication use in elderly individuals with and without dry mouths
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Lee KA, Park JC, Park YK
- KMID: 2471882
- Nutr Res Pract.
- 2020 Apr;14(2):143-151.
- doi: 10.4162/nrp.2020.14.2.143
BACKGROUND/OBJECTIVES: The nutrition of the elderly depends on various factors. Oral health, especially oral dryness, can be an important risk factor. In this study, we attempted to determine whether dry... -
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- Novel ABCD1 Gene Mutation in a Korean Patient with X-Linked Adrenoleukodystrophy Presenting with Addison's Disease
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Cho YK, Lee SY, Kim SW
- KMID: 2471735
- Endocrinol Metab.
- 2020 Mar;35(1):188-191.
- doi: 10.3803/EnM.2020.35.1.188
X-linked adrenoleukodystrophy (X-ALD) occurs due to mutations in the ABCD1 gene that encodes the peroxisomal membrane protein peroxisomal transporter ATP-binding cassette sub-family D member 1 (ABCD1). Degradation of very long-chain... -
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- Imbalance of Gut Streptococcus, Clostridium, and Akkermansia Determines the Natural Course of Atopic Dermatitis in Infant
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Park YM, Lee SY, Kang MJ, Kim BS, Lee MJ, Jung SS, Yoon JS, Cho HJ, Lee E, Yang SI, Seo JH, Kim HB, Suh DI, Shin YH, Kim KW, Ahn K, Hong SJ
- KMID: 2468465
- Allergy Asthma Immunol Res.
- 2020 Mar;12(2):322-337.
- doi: 10.4168/aair.2020.12.2.322
PURPOSE: The roles of gut microbiota on the natural course of atopic dermatitis (AD) are not yet fully understood. We investigated whether the composition and function of gut microbiota and... -
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- Efficacy and Safety of Omega-3 Fatty Acids in Patients Treated with Statins for Residual Hypertriglyceridemia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
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Jun JE, Jeong IK, Yu JM, Kim SR, Lee IK, Han KA, Choi SH, Kim SK, Park HK, Mok JO, Lee YH, Kwon HS, Kim SH, Kang HC, Lee SA, Lee CB, Choi KM, Her SH, Shin WY, Shin MS, Ahn HS, Kang SH, Cho JM, Jo SH, Cha TJ, Kim SY, Won KH, Kim DB, Lee JH, Lee MK
- KMID: 2470957
- Diabetes Metab J.
- 2020 Feb;44(1):78-90.
- doi: 10.4093/dmj.2018.0265
BACKGROUND: Cardiovascular risk remains increased despite optimal low density lipoprotein cholesterol (LDL-C) level induced by intensive statin therapy. Therefore, recent guidelines recommend non-high density lipoprotein cholesterol (non-HDL-C) as a secondary... -
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- Quantifications of Lipid Kinetics In Vivo Using Stable Isotope Tracer Methodology
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Kim IY, Park S, Jang J, Wolfe RR
- KMID: 2470804
- J Lipid Atheroscler.
- 2020 Jan;9(1):110-123.
- doi: 10.12997/jla.2020.9.1.110
Like other bodily materials, lipids such as plasma triacylglycerol, cholesterols, and free fatty acids are in a dynamic state of constant turnover (i.e., synthesis, breakdown, oxidation, and/or conversion to other... -
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- Ceramides: Nutrient Signals that Drive Hepatosteatosis
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Summers SA
- KMID: 2470800
- J Lipid Atheroscler.
- 2020 Jan;9(1):50-65.
- doi: 10.12997/jla.2020.9.1.50
Ceramides are minor components of the hepatic lipidome that have major effects on liver function. These products of lipid and protein metabolism accumulate when the energy needs of the hepatocyte... -
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- Impact of Intravenous Omega-3-Enriched Lipid Emulsion on Liver Enzyme and Triglyceride Serum Levels of Children Undergoing Gastrointestinal Surgery
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Hanindita , Widjaja NA, Irawan R, Hidayat B, Hariastawa IA
- KMID: 2467898
- Pediatr Gastroenterol Hepatol Nutr.
- 2020 Jan;23(1):98-104.
- doi: 10.5223/pghn.2020.23.1.98
PURPOSE: To investigate the impact of omega-3-enriched lipid emulsion (LE) on liver enzyme (aspartate transaminase [AST] and alanine aminotransferase [ALT]) and triglyceride (TG) levels of children undergoing gastrointestinal surgery. METHODS: This... -
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- Medium- and long-chain triglyceride propofol reduces the activity of acetyl-coenzyme A carboxylase in hepatic lipid metabolism in HepG2 and Huh7 cells
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Wang LY, Wu J, Gao YF, Lin DM, Ma J
- KMID: 2466566
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):19-26.
- doi: 10.4196/kjpp.2020.24.1.19
Medium- and long-chain triglyceride (MCT/LCT) propofol is widely used as an intravenous anesthetic, especially in the intensive care unit. The present study aimed to assess whether MCT/LCT propofol is safe... -
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- Antibiotics-Induced Dysbiosis of Intestinal Microbiota Aggravates Atopic Dermatitis in Mice by Altered Short-Chain Fatty Acids
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Kim HJ, Lee SH, Hong SJ
- KMID: 2462578
- Allergy Asthma Immunol Res.
- 2020 Jan;12(1):137-148.
- doi: 10.4168/aair.2020.12.1.137
PURPOSE: Alterations in the intestinal microbiota in early life affects the development of atopic dermatitis (AD) in humans. This study aimed to further investigate the effects of gut dysbiosis in... -
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- Association between Omega Fatty Acid Intake and Suicidality : Sex Differences in the General Korean Population
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Hur YI, Lee JH
- KMID: 2470707
- Korean J Psychosom Med.
- 2019 Dec;27(2):181-190.
- doi: 10.22722/KJPM.2019.27.2.181
OBJECTIVES: Epidemiological studies in other countries show that a low intake of omega-3 fatty acids (FAs) increases the risk of depression or suicidality. However, no studies have investigated the associations... -
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- Effect of Diet on the Gut Microbiota Associated with Obesity
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Kim B, Choi HN, Yim JE
- KMID: 2470289
- J Obes Metab Syndr.
- 2019 Dec;28(4):216-224.
- doi: 10.7570/jomes.2019.28.4.216
Obesity is abnormal or excessive fat accumulation that is associated with progression of metabolic diseases including type 2 diabetes mellitus, cardiovascular disease, nonalcoholic fatty liver disease, and cancer. Gut microbiota... -
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- Identification of Soluble Epoxide Hydrolase Inhibitors from the Seeds of Passiflora edulis Cultivated in Vietnam
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Cuong TD, Thi Ngoc Anh H, Huong TT, Khanh PN, Ha VT, Hung TM, Kim YH, Cuong NM
- KMID: 2468069
- Nat Prod Sci.
- 2019 Dec;25(4):348-353.
- doi: 10.20307/nps.2019.25.4.348
Soluble epoxide hydrolases (sEH) are enzymes present in all living organisms, metabolize epoxy fatty acids to 1,2-diols. sEH in the metabolism of polyunsaturated fatty acids plays a key role in... -
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- Physiological Activities of Policosanol Extracted from Sugarcane Wax
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Jang YS, Kim DE, Han E, Jung J
- KMID: 2468061
- Nat Prod Sci.
- 2019 Dec;25(4):293-297.
- doi: 10.20307/nps.2019.25.4.293
Policosanol extracted from sugarcane wax is a generic term used for total fatty alcohols obtained from esterification of fatty acids. It has been approved as a health functional food by... -
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- Metformin Ameliorates Lipotoxic β-Cell Dysfunction through a Concentration-Dependent Dual Mechanism of Action
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Kim HI, Lee JS, Kwak BK, Hwang WM, Kim MJ, Kim YB, Chung SS, Park KS
- KMID: 2466506
- Diabetes Metab J.
- 2019 Dec;43(6):854-866.
- doi: 10.4093/dmj.2018.0179
BACKGROUND: Chronic exposure to elevated levels of free fatty acids contributes to pancreatic β-cell dysfunction. Although it is well known that metformin induces cellular energy depletion and a concomitant activation... -
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- A Novel Effect of Lipids Extracted from Vernix Caseosa on Regulation of Filaggrin Expression in Human Epidermal Keratinocytes
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Qiao W, Jia T, Gu H, Guo R, Kaku K, Wu W
- KMID: 2461983
- Ann Dermatol.
- 2019 Dec;31(6):611-620.
- doi: 10.5021/ad.2019.31.6.611
BACKGROUND: Vernix caseosa (VC), which is known as a unique human substance, is a biofilm that covers the skin of most human newborns. VC has many biological functions including anti-infective,... -
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- Nutritional issues in patients with cancer
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Kim DH
- KMID: 2465811
- Intest Res.
- 2019 Oct;17(4):455-462.
- doi: 10.5217/ir.2019.00076
Cancer is a catabolic inflammatory disease that causes patients to often experience weight loss, or even cachexia in severe cases. Undernourishment in patients with cancer impairs the quality of life... -
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- Effect of immune-enhancing enteral nutrition formula enriched with plant-derived n-3 fatty acids on natural killer cell activity in rehabilitation patients
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Cho JM, Choi HS, Cho YS, Park SY, Kim DY, Lee JH
- KMID: 2464117
- Nutr Res Pract.
- 2019 Oct;13(5):384-392.
- doi: 10.4162/nrp.2019.13.5.384
BACKGROUND/OBJECTIVES: Enteral nutrition formulas with immune-enhancing nutrients, such as n-3 fatty acids, may manage patients' nutritional status and pathophysiological processes. The aim of our study was to investigate natural killer... -
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- PF-04620110, a Potent Antidiabetic Agent, Suppresses Fatty Acid-Induced NLRP3 Inflammasome Activation in Macrophages
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Jo SI, Bae JH, Kim SJ, Lee JM, Jeong JH, Moon JS
- KMID: 2460961
- Diabetes Metab J.
- 2019 Oct;43(5):683-699.
- doi: 10.4093/dmj.2019.0112
BACKGROUND: Chronic inflammation has been linked to insulin resistance and type 2 diabetes mellitus (T2DM). High-fat diet (HFD)-derived fatty acid is associated with the activation of chronic inflammation in T2DM.... -
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- Comparison of the Efficacy of Rosuvastatin Monotherapy 20 mg with Rosuvastatin 5 mg and Ezetimibe 10 mg Combination Therapy on Lipid Parameters in Patients with Type 2 Diabetes Mellitus
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Hwang YC, Jun JE, Jeong IK, Ahn KJ, Chung HY
- KMID: 2460952
- Diabetes Metab J.
- 2019 Oct;43(5):582-589.
- doi: 10.4093/dmj.2018.0124
BACKGROUND: The apolipoprotein B/A1 (apoB/A1) ratio is a stronger predictor of future cardiovascular disease than is the level of conventional lipids. Statin and ezetimibe combination therapy have shown additional cardioprotective... -
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- Efficacy and Safety of Prescription Omega-3 Fatty Acids Added to Stable Statin Therapy in Korean Patients with Type 2 Diabetes and Hypertriglyceridemia: a Randomized Controlled Trial
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Son JW, Kim CH, Nam MS, Park IB, Yoo SJ
- KMID: 2458387
- J Lipid Atheroscler.
- 2019 Sep;8(2):221-231.
- doi: 10.12997/jla.2019.8.2.221
OBJECTIVE: The aim of this study was to investigate the effects of omega-3 fatty acids added to statin monotherapy in Korean patients with type 2 diabetes who have persistent hypertriglyceridemia... -
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