- New Therapeutic Options for Autism Spectrum Disorder: Experimental Evidences
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Penagarikano O
- KMID: 2165566
- Exp Neurobiol.
- 2015 Dec;24(4):301-311.
- doi: 10.5607/en.2015.24.4.301
Autism spectrum disorder (ASD) is characterized by impairment in two behavioral domains: social interaction/communication together with the presence of stereotyped behaviors and restricted interests. The heterogeneity in the phenotype among... -
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- Genetics of Autism Spectrum Disorder: Current Status and Possible Clinical Applications
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Yoo H
- KMID: 2165563
- Exp Neurobiol.
- 2015 Dec;24(4):257-272.
- doi: 10.5607/en.2015.24.4.257
Autism spectrum disorder (ASD) is one of the most complex behavioral disorders with a strong genetic influence. The objectives of this article are to review the current status of genetic... -
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- Exploring the Validity of Valproic Acid Animal Model of Autism
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Mabunga DF, Gonzales E, Kim JW, Kim KC, Shin CY
- KMID: 2165565
- Exp Neurobiol.
- 2015 Dec;24(4):285-300.
- doi: 10.5607/en.2015.24.4.285
The valproic acid (VPA) animal model of autism spectrum disorder (ASD) is one of the most widely used animal model in the field. Like any other disease models, it can't... -
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- The Role of Oxidative Stress in Neurodegenerative Diseases
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Kim GH, Kim JE, Rhie SJ, Yoon S
- KMID: 2165568
- Exp Neurobiol.
- 2015 Dec;24(4):325-340.
- doi: 10.5607/en.2015.24.4.325
Oxidative stress is induced by an imbalanced redox states, involving either excessive generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system. The brain is one of organs... -
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- Intracranial Vasospasm without Intracranial Hemorrhage due to Acute Spontaneous Spinal Subdural Hematoma
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Oh JH, Jwa SJ, Yang TK, Lee CS, Oh K, Kang JH
- KMID: 2165572
- Exp Neurobiol.
- 2015 Dec;24(4):366-370.
- doi: 10.5607/en.2015.24.4.366
Spontaneous spinal subdural hematoma (SDH) is very rare. Furthermore, intracranial vasospasm (ICVS) associated with spinal hemorrhage has been very rarely reported. We present an ICVS case without intracranial hemorrhage following... -
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- Characteristics of Brains in Autism Spectrum Disorder: Structure, Function and Connectivity across the Lifespan
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Ha S, Sohn IJ, Kim N, Sim HJ, Cheon KA
- KMID: 2165564
- Exp Neurobiol.
- 2015 Dec;24(4):273-284.
- doi: 10.5607/en.2015.24.4.273
Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental disorder characterized by impaired social communication and restricted and repetitive behaviors (RRBs). Over the past decade, neuroimaging studies have provided considerable... -
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- Is Oxytocin Application for Autism Spectrum Disorder Evidence-Based?
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Lee SY, Lee AR, Hwangbo R, Han J, Hong M, Bahn GH
- KMID: 2165567
- Exp Neurobiol.
- 2015 Dec;24(4):312-324.
- doi: 10.5607/en.2015.24.4.312
Autism spectrum disorder (ASD) is characterized by persistent deficits within two core symptom domains: social communication and restricted, repetitive behaviors. Although numerous studies have reported psychopharmacological treatment outcomes for the... -
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- Rosmarinic Acid Alleviates Neurological Symptoms in the G93A-SOD1 Transgenic Mouse Model of Amyotrophic Lateral Sclerosis
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Seo JS, Choi J, Leem YH, Han PL
- KMID: 2165569
- Exp Neurobiol.
- 2015 Dec;24(4):341-350.
- doi: 10.5607/en.2015.24.4.341
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects motor neurons in the brain and spinal cord, resulting in paralysis of voluntary skeletal muscles and eventually death, usually within... -
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- Pattern of Respiratory Deterioration in Sporadic Amyotrophic Lateral Sclerosis According to Onset Lesion by Using Respiratory Function Tests
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Kim DG, Hong YH, Shin JY, Lee KW, Park KS, Seong SY, Sung JJ
- KMID: 2165570
- Exp Neurobiol.
- 2015 Dec;24(4):351-357.
- doi: 10.5607/en.2015.24.4.351
Most amyotrophic lateral sclerosis (ALS) patients show focal onset of upper and lower motor neuron signs and spread of symptoms to other regions or the other side clinically. Progression patterns... -
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- The Effect of Donor-Dependent Administration of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells following Focal Cerebral Ischemia in Rats
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Park HW, Chang JW, Yang YS, Oh W, Hwang JH, Kim DG, Paek SH
- KMID: 2165571
- Exp Neurobiol.
- 2015 Dec;24(4):358-365.
- doi: 10.5607/en.2015.24.4.358
Stroke is an ischemic disease caused by clotted vessel-induced cell damage. It is characterized by high morbidity and mortality and is typically treated with a tissue plasminogen activator (tPA). However,... -
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