- Spike Frequency Adaptation in Neurons of the Central Nervous System
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Ha GE, Cheong E
- KMID: 2389004
- Exp Neurobiol.
- 2017 Aug;26(4):179-185.
- doi: 10.5607/en.2017.26.4.179
Neuronal firing patterns and frequencies determine the nature of encoded information of the neurons. Here we discuss the molecular identity and cellular mechanisms of spike-frequency adaptation in central nervous system... -
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- Toll-like Receptor 2: A Novel Therapeutic Target for Ischemic White Matter Injury and Oligodendrocyte Death
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Choi JY, Kim BG
- KMID: 2389005
- Exp Neurobiol.
- 2017 Aug;26(4):186-194.
- doi: 10.5607/en.2017.26.4.186
Despite paramount clinical significance of white matter stroke, there is a paucity of researches on the pathomechanism of ischemic white matter damage and accompanying oligodendrocyte (OL) death. Therefore, a large... -
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- TLR5 Activation through NF-κB Is a Neuroprotective Mechanism of Postconditioning after Cerebral Ischemia in Mice
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Jeong J, Kim S, Lim DS, Kim SH, Doh H, Kim SD, Song YS
- KMID: 2389008
- Exp Neurobiol.
- 2017 Aug;26(4):213-226.
- doi: 10.5607/en.2017.26.4.213
Postconditioning has been shown to protect the mouse brain from ischemic injury. However, the neuroprotective mechanisms of postconditioning remain elusive. We have found that toll-like receptor 5 (TLR5) plays an... -
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- Decreased Glial GABA and Tonic Inhibition in Cerebellum of Mouse Model for Attention-Deficit/Hyperactivity Disorder (ADHD)
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Kim YS, Woo J, Lee CJ, Yoon BE
- KMID: 2389007
- Exp Neurobiol.
- 2017 Aug;26(4):206-212.
- doi: 10.5607/en.2017.26.4.206
About 5~12% of school-aged children suffer from the Attention-Deficit/Hyperactivity Disorder (ADHD). However, the core mechanism of ADHD remains unclear. G protein-coupled receptor kinase-interacting protein-1 (GIT1) has recently been reported to... -
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- NOX Inhibitors - A Promising Avenue for Ischemic Stroke
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Kim JY, Park J, Lee JE, Yenari MA
- KMID: 2389006
- Exp Neurobiol.
- 2017 Aug;26(4):195-205.
- doi: 10.5607/en.2017.26.4.195
NADPH-oxidase (NOX) mediated superoxide originally found on leukocytes, but now recognized in several types of cells in the brain. It has been shown to play an important role in the... -
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- Anti-inflammatory Effect of Glucagon Like Peptide-1 Receptor Agonist, Exendin-4, through Modulation of IB1/JIP1 Expression and JNK Signaling in Stroke
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Kim S, Jeong J, Jung HS, Kim B, Kim YE, Lim DS, Kim SD, Song YS
- KMID: 2389009
- Exp Neurobiol.
- 2017 Aug;26(4):227-239.
- doi: 10.5607/en.2017.26.4.227
Glucagon like peptide-1 (GLP-1) stimulates glucose-dependent insulin secretion. Dipeptidyl peptidase-4 (DPP-4) inhibitors, which block inactivation of GLP-1, are currently in clinical use for type 2 diabetes mellitus. Recently, GLP-1 has... -
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