- A Short Review on the Current Understanding of Autism Spectrum Disorders
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Park HR, Lee JM, Moon HE, Lee DS, Kim BN, Kim J, Kim DG, Paek SH
- KMID: 2165573
- Exp Neurobiol.
- 2016 Feb;25(1):1-13.
- doi: 10.5607/en.2016.25.1.1
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders characterized by a deficit in social behaviors and nonverbal interactions such as reduced eye contact, facial expression, and body gestures... -
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- Blood Transcriptome Profiling in Myasthenia Gravis Patients to Assess Disease Activity: A Pilot RNA-seq Study
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Park KH, Jung J, Lee JH, Hong YH
- KMID: 2165577
- Exp Neurobiol.
- 2016 Feb;25(1):40-47.
- doi: 10.5607/en.2016.25.1.40
Myasthenia gravis (MG) is an antibody-mediated autoimmune disease characterized by exertional weakness. There is no biomarker to reflect disease activity and guide treatment decision. Here, we reported a pilot blood... -
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- Agmatine Ameliorates High Glucose-Induced Neuronal Cell Senescence by Regulating the p21 and p53 Signaling
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Song J, Lee B, Kang S, Oh Y, Kim E, Kim CH, Song HT, Lee JE
- KMID: 2165575
- Exp Neurobiol.
- 2016 Feb;25(1):24-32.
- doi: 10.5607/en.2016.25.1.24
Neuronal senescence caused by diabetic neuropathy is considered a common complication of diabetes mellitus. Neuronal senescence leads to the secretion of pro-inflammatory cytokines, the production of reactive oxygen species, and... -
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- Drosophila Homolog of Human KIF22 at the Autism-Linked 16p11.2 Loci Influences Synaptic Connectivity at Larval Neuromuscular Junctions
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Park SM, Littleton , Park HR, Lee JH
- KMID: 2165576
- Exp Neurobiol.
- 2016 Feb;25(1):33-39.
- doi: 10.5607/en.2016.25.1.33
Copy number variations at multiple chromosomal loci, including 16p11.2, have recently been implicated in the pathogenesis of autism spectrum disorder (ASD), a neurodevelopmental disease that affects 1~3% of children worldwide.... -
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- Differential Cellular Tropism of Lentivirus and Adeno-Associated Virus in the Brain of Cynomolgus Monkey
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An H, Cho DW, Lee SE, Yang YS, Han SC, Lee CJ
- KMID: 2165578
- Exp Neurobiol.
- 2016 Feb;25(1):48-54.
- doi: 10.5607/en.2016.25.1.48
Many researchers are using viruses to deliver genes of interest into the brains of laboratory animals. However, certain target brain cells are not easily infected by viruses. Moreover, the differential... -
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- PINK1 Deficiency Decreases Expression Levels of mir-326, mir-330, and mir-3099 during Brain Development and Neural Stem Cell Differentiation
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Choi I, Woo JH, Jou I, Joe EH
- KMID: 2165574
- Exp Neurobiol.
- 2016 Feb;25(1):14-23.
- doi: 10.5607/en.2016.25.1.14
PTEN-induced putative kinase 1 (PINK1) is a Parkinson's disease (PD) gene. We examined miRNAs regulated by PINK1 during brain development and neural stem cell (NSC) differentiation, and found that lvels... -
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