- Exogenous rhTRX reduces lipid accumulation under LPS-induced inflammation
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Han GY, Lee EK, Park HW, Kim HJ, Kim CW
- KMID: 2155336
- Exp Mol Med.
- 2014 Jan;46(1):e71.
- doi: 10.1038/emm.2013.136
Redox-regulating molecule, recombinant human thioredoxin (rhTRX) which shows anti-inflammatory, and anti-oxidative effects against lipopolysaccharide (LPS)-stimulated inflammation and regulate protein expression levels. LPS-induced reactive oxygen intermediates (ROI) and NO production were... -
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- Regulation of anti-inflammatory cytokines IL-10 and TGF-beta in mouse dendritic cells through treatment with Clonorchis sinensis crude antigen
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Jin Y, Wi HJ, Choi MH, Hong ST, Bae YM
- KMID: 2155339
- Exp Mol Med.
- 2014 Jan;46(1):e74.
- doi: 10.1038/emm.2013.144
Dendritic cells (DCs), which are regarded as the most potent antigen-presenting cells, are involved in innate and adaptive immunity. Upon uptake of pathogens, DCs express cell surface markers and secrete... -
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- The role of adiponectin in the production of IL-6, IL-8, VEGF and MMPs in human endothelial cells and osteoblasts: implications for arthritic joints
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Lee YA, Ji HI, Lee SH, Hong SJ, Yang HI, Chul Yoo M, Kim KS
- KMID: 2155337
- Exp Mol Med.
- 2014 Jan;46(1):e72.
- doi: 10.1038/emm.2013.141
This study was performed to evaluate the contribution of adiponectin to the production of interleukin (IL)-6, IL-8, vascular endothelial growth factor (VEGF), matrix metalloproteinase (MMP)-1 and MMP-13 in human endothelial... -
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- Cilostazol inhibits insulin-stimulated expression of sterol regulatory binding protein-1c via inhibition of LXR and Sp1
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Jung YA, Kim HK, Bae KH, Seo HY, Kim HS, Jang BK, Jung GS, Lee IK, Kim MK, Park KG
- KMID: 2155338
- Exp Mol Med.
- 2014 Jan;46(1):e73.
- doi: 10.1038/emm.2013.143
Hepatic steatosis is common in obese individuals with hyperinsulinemia and is an important hepatic manifestation of metabolic syndrome. Sterol regulatory binding protein-1c (SREBP-1c) is a master regulator of lipogenic gene... -
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- Mesenchymal stem cells reciprocally regulate the M1/M2 balance in mouse bone marrow-derived macrophages
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Cho DI, Kim MR, Jeong HY, Jeong HC, Jeong MH, Yoon SH, Kim YS, Ahn Y
- KMID: 2155335
- Exp Mol Med.
- 2014 Jan;46(1):e70.
- doi: 10.1038/emm.2013.135
Mesenchymal stem cells (MSCs) have been widely studied for their applications in stem cell-based regeneration. During myocardial infarction (MI), infiltrated macrophages have pivotal roles in inflammation, angiogenesis and cardiac remodeling.... -
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