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A Rapid Assessing Method of Drug Susceptibility Using Flow Cytometry for Mycobacterium tuberculosis Isolates Resistant to Isoniazid, Rifampin, and Ethambutol

Lee SK, Baek SH, Hong MS, Lee JS, Cho EJ, Lee JI, Cho SN, Eum SY

Background: The current conventional drug susceptibility test (DST) for Mycobacterium tuberculosis (Mtb) takes several weeks of incubation to obtain results. As a rapid method, molecular DST requires only a few...
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Potential Role of Immunodiagnosis for Pulmonary Tuberculosis Using Induced Sputum Cells

Jeon D, Lee SE, Cho WH, Lee BH, Kim YS, Lee JE, Son ES, Lee YJ, Hong MS, Eum SY

PURPOSE: To evaluate the diagnostic utility and predictors for determinate results of an enzyme-linked immunospot assay using induced sputum cells (IS ELISPOT) for a rapid diagnosis of pulmonary tuberculosis (TB). MATERIALS...
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Kinetics of IFN-Gamma and TNF-Alpha Gene Expression and Their Relationship with Disease Progression after Infection with Mycobacterium Tuberculosis in Guinea Pigs

Roh IS, Cho S, Eum SY, Cho SN

PURPOSE: Guinea pig is one of the most suitable animal models for Mycobacterium tuberculosis (M. tb) infection since it shows similarities to pulmonary infection in humans. Although guinea pig shows...
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