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Consideration of EphA2 in relation to epithelial-mesenchymal transition in uterine endometrial cancer

Hwang JY

No abstract available.
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Aberrant Expression of Epithelial-Mesenchymal Transition Markers in Early Gastric Cancer: Clinical Application

Joo MK

No abstract available.
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Membrane Proteins Involved in Epithelial-Mesenchymal Transition and Tumor Invasion: Studies on TMPRSS4 and TM4SF5

Kim S, Lee JW

The epithelial-mesenchymal transition (EMT) is one mechanism by which cells with mesenchymal features can be generated and is a fundamental event in morphogenesis. Recently, invasion and metastasis of cancer cells...
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The Potential Role of Elk-3/Egr-1 Signaling Pathway in the Epithelial-Mesenchymal Transition during Liver Fibrosis

Kim IH

No abstract available.
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Epithelial Mesenchymal Transition in Drug Resistance and Metastasis of Lung Cancer

Nurwidya F, Takahashi , Murakami A, Takahashi

  • KMID: 1972722
  • Cancer Res Treat.
  • 2012 Sep;44(3):151-156.
Among all types of cancer, incidence of lung cancer remains the highest with regard to cancer-related mortality. Problems contributing to recurrence of the disease include metastasis and drug resistance. Mounting...
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Role of Gastric Stem Cells in Gastric Carcinogenesis by Chronic Helicobacter pylori Infection

Park MI, Heo J

Gastric cancer is a disease with the second cancer-related mortality in the world. Helicobacter pylori infection that is one of major causes of gastric carcinogenesis induces a chronic inflammation in...
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The Role of Epithelial-mesenchymal Transition in the Gastroenterology

Kim SM, Han JH, Park SM

The epithelial-mesenchymal transition (EMT) plays physiologic roles in the embryogenesis, wound healing, and tissue regeneration. In terms of pathological direction, it causes organ fibrosis, cancer development, progression, metastasis, and chemoresistance....
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Role of the Epithelial-Mesenchymal Transition in Bladder Cancer: From Prognosis to Therapeutic Target

Yun SJ, Kim WJ

  • KMID: 2315980
  • Korean J Urol.
  • 2013 Oct;54(10):645-650.
Bladder cancer (BC) is the second most common malignancy of urological organs. However, patients with non-muscle-invasive BC are at high risk of recurrence and progression into muscle-invasive BC, and the...
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Phosphorylation and Reorganization of Keratin Networks: Implications for Carcinogenesis and Epithelial Mesenchymal Transition

Kim HJ, Choi WJ, Lee CH

Metastasis is one of hallmarks of cancer and a major cause of cancer death. Combatting metastasis is highly challenging. To overcome these difficulties, researchers have focused on physical properties of...
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The Epithelial-Mesenchymal Transition and E-cadherin and Vimentin Expression in Basal Cell Carcinoma and Squamous Cell Carcinoma

Kim YU, Kim KJ, Heo EP

  • KMID: 2246223
  • Korean J Dermatol.
  • 2015 Feb;53(2):96-105.
BACKGROUND: The epithelial-mesenchymal transition (EMT) in epithelial tumor cells plays a key role in tumor invasion and metastasis. The reduction or loss of E-cadherin and the acquisition of vimentin are...
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Epithelial-mesenchymal transition in keloid tissue

Yang CE, Moon SJ, Kim SJ, Lee JH, Yun CO, Lew DH, Lee WJ

No abstract available.
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Immunohistochemical Expression of Epithelial-Mesenchymal Transition Markers in Early Gastric Cancer: Cancer Tissue versus Noncancer Tissue

Jung HJ, Hong SJ, Kim SH

BACKGROUND/AIMS: Epithelial-mesenchymal transition (EMT) is a developmental process, wherein the epithelial cells show reduced intercellular adhesions and acquire migratory fibroblastic properties. EMT is associated with downregulation in epithelial marker expression,...
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Epithelial to Mesenchymal Transition of Mesothelial Cells in Tuberculous Pleurisy

Kim C, Kim DG, Park SH, Hwang YI, Jang SH, Kim CH, Jung KS, Min K, Lee JW, Jang YS

PURPOSE: Tuberculous pleurisy is the most frequent extrapulmonary manifestation of tuberculosis. In spite of adequate treatment, pleural fibrosis is a common complication, but the mechanism has not been elucidated. This...
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The Crucial Role of Cholangiocytes in Cholangiopathies

Park SM

  • KMID: 2053490
  • Gut Liver.
  • 2012 Jul;6(3):295-304.
Cholangiopathies are diseases involving the intrahepatic biliary tree. They appear to involve, chronic inflammation of the bile ducts, which can lead to the development of bile duct cholestasis, proliferation/ductopenia, biliary...
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Role of the epithelial-mesenchymal transition and its effects on embryonic stem cells

Kim YS, Yi BR, Kim NH, Choi KC

The epithelial-mesenchymal transition (EMT) is important for embryonic development and the formation of various tissues or organs. However, EMT dysfunction in normal cells leads to diseases, such as cancer or...
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Pathogenesis and New Diagnosis Guideline of Idiopathic Pulmonary Fibrosis

Uh ST

  • KMID: 2082451
  • Korean J Med.
  • 2013 Apr;84(4):481-488.
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal fibrotic lung disease in many patients. In spite of extensive research for many decades, the exact pathogenesis of IPF is unknown....
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Wheatgrass extract inhibits hypoxia-inducible factor-1-mediated epithelial-mesenchymal transition in A549 cells

Do NY, Shin HJ, Lee JE

BACKGROUND/OBJECTIVES: Epithelial-mesenchymal transition (EMT) is involved in not only cancer development and metastasis but also non-cancerous conditions. Hypoxia is one of the proposed critical factors contributing to formation of chronic...
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Loss of E-cadherin and Acquisition of Vimentin in Epithelial-Mesenchymal Transition are Noble Indicators of Uterine Cervix Cancer Progression

Myong NH

BACKGROUND: Epithelial-mesenchymal transition (EMT) has been known to play a key role in the stromal invasion of carcinoma in situ (CIS) lesion. Loss of E-cadherin and acquisition of vimentin are...
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p90RSK Activation Promotes Epithelial-Mesenchymal Transition in Cisplatin-Treated Triple-Negative Breast Cancer Cells

Jin Y, Heo KS

p90 ribosomal S6 kinase (p90RSK), one of the downstream effectors in ERK1/2 pathways, shows high expression in human breast cancer tissues. However, its role in breast cancer development and drug...
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Epithelial-mesenchymal transition in osteogenic sarcoma of the neck following oral squamous cell carcinoma

Kim HS, Kim NH, Han SH, Cha IH, Seo DJ, Park W, Yook JI, Kim HJ

Postirradiation extraosseous osteogenic sarcomas are uncommon in the head and neck, despite the extensive use of high-dose radiation. It has been described as de novo radiation-induced neoplasm. We present a...
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