- Next-Generation Sequencing and Epigenomics Research: A Hammer in Search of Nails
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Sarda S, Hannenhalli S
- KMID: 1708243
- Genomics Inform.
- 2014 Mar;12(1):2-11.
- doi: 10.5808/GI.2014.12.1.2
After the initial enthusiasm of the human genome project, it became clear that without additional data pertaining to the epigenome, i.e., how the genome is marked at specific developmental periods,... -
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- Year-in-Review of Lung Cancer
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Son JW
- KMID: 1842908
- Tuberc Respir Dis.
- 2012 Sep;73(3):137-142.
- doi: 10.4046/trd.2012.73.3.137
In the last several years, we have made slow but steady progress in understanding molecular biology of lung cancer. This review is focused on advances in understanding the biology of... -
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- Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective
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Lent H, Lee KE, Park HS
- KMID: 2166531
- Genomics Inform.
- 2015 Dec;13(4):152-155.
- doi: 10.5808/GI.2015.13.4.152
Recently, the Encyclopedia of DNA Elements (ENCODE) Analysis Working Group converted data from ChIP-seq analyses from the Broad Histone track into 15 corresponding chromatic maps that label sequences with different... -
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- Genomics and proteomics in stem cell research: the road ahead
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Ahn SM, Simpson R, Lee B
- KMID: 2168892
- Anat Cell Biol.
- 2010 Mar;43(1):1-14.
- doi: 10.5115/acb.2010.43.1.1
Stem cell research has been widely studied over the last few years and has attracted increasing attention from researchers in all fields of medicine due to its potential to treat... -
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- Role of Putative Epigenetic Mechanisms in the Intergenerational Transmission of Trauma Effects in “Comfort Women†Survivor Offspring
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Park SC
- KMID: 2451944
- Psychiatry Investig.
- 2019 Jun;16(6):475-476.
- doi: 10.30773/pi.2019.05.01
No abstract available. -
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- Researches of Epigenetic Epidemiology for Infections and Radiation as Carcinogen
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Bae JM
- KMID: 2418814
- J Prev Med Public Health.
- 2018 Jul;51(4):169-172.
- doi: 10.3961/jpmph.18.070
In recent years, a number of studies have been reported on the various types of cancer arising from epigenetic alterations, including reports that these epigenetic alterations occur as a result... -
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- Potential Epigenetic Biomarkers for Prostate Cancer Screening
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Bae JM
- KMID: 2417787
- Int Neurourol J.
- 2018 Jun;22(2):142-144.
- doi: 10.5213/inj.1836096.048
No abstract available. -
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- Epigenetics of Male Fertility: Effects on Assisted Reproductive Techniques
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Giacone F, Cannarella R, Mongioì L, Alamo A, Condorelli RA, Calogero A, La Vignera S
- KMID: 2443230
- World J Mens Health.
- 2019 May;37(2):148-156.
- doi: 10.5534/wjmh.180071
During the last decades the study of male infertility and the introduction of the assisted reproductive techniques (ARTs) has allowed to understand that normal sperm parameters do not always predict... -
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- Epigenetic Regulation of RUNX3 in Thyroid Carcinoma
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Joung KH, Shong M
- KMID: 2432929
- Korean J Intern Med.
- 2012 Dec;27(4):391-393.
No abstract available. -
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- Epigenomic Hard Drive Imprinting: A Hidden Code Beyond the Biological Death of Cancer Patients
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Nilendu P, Sharma NK
- KMID: 2434282
- J Cancer Prev.
- 2017 Dec;22(4):211-218.
- doi: 10.15430/JCP.2017.22.4.211
Several genetic and epigenetic theories have been suggested to explain the intricacies of life and death. However, several questions remain unsettled regarding cellular death events, particularly of living tissue in... -
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- Epigenetic Alterations in Inflammatory Bowel Disease and Cancer
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Yi JM, Kim TO
- KMID: 2284877
- Intest Res.
- 2015 Apr;13(2):112-121.
- doi: 10.5217/ir.2015.13.2.112
Overwhelming evidences supports the idea that inflammatory bowel disease (IBD) is caused by a complex interplay between genetic alterations of multiple genes and an aberrant interaction with environmental factors. There... -
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- Epigenetic Modifications: Novel Therapeutic Approach for Thyroid Cancer
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Zhu X, Cheng SY
- KMID: 2389812
- Endocrinol Metab.
- 2017 Sep;32(3):326-331.
- doi: 10.3803/EnM.2017.32.3.326
The incidence of thyroid cancer is growing the fastest among all cancers in the United States, especially in women. The number of patients with thyroid neoplasm is part of an... -
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- A Review of Three Different Studies on Hidden Markov Models for Epigenetic Problems: A Computational Perspective
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Lee KE, Park HS
- KMID: 2391489
- Genomics Inform.
- 2014 Dec;12(4):145-150.
- doi: 10.5808/GI.2014.12.4.145
Recent technical advances, such as chromatin immunoprecipitation combined with DNA microarrays (ChIp-chip) and chromatin immunoprecipitation-sequencing (ChIP-seq), have generated large quantities of high-throughput data. Considering that epigenomic datasets are arranged over... -
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- Trans-differentiation via Epigenetics: A New Paradigm in the Bone Regeneration
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Cho YD, Ryoo HM
- KMID: 2406234
- J Bone Metab.
- 2018 Feb;25(1):9-13.
- doi: 10.11005/jbm.2018.25.1.9
In regenerative medicine, growing cells or tissues in the laboratory is necessary when damaged cells can not heal by themselves. Acquisition of the required cells from the patient's own cells... -
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- Epigenetic modifications and diabetic nephropathy
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Reddy MA, Park JT, Natarajan
- KMID: 2224212
- Kidney Res Clin Pract.
- 2012 Sep;31(3):139-150.
Diabetic nephropathy (DN) is a major complication associated with both type 1 and type 2 diabetes, and a leading cause of end-stage renal disease. Conventional therapeutic strategies are not fully... -
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- Single-Cell Sequencing in Cancer: Recent Applications to Immunogenomics and Multi-omics Tools
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Sierant MC, Choi J
- KMID: 2439207
- Genomics Inform.
- 2018 Dec;16(4):e17.
- doi: 10.5808/GI.2018.16.4.e17
Tumor heterogeneity, the cellular mosaic of multiple lineages arising from the process of clonal evolution, has continued to thwart multi-omics analyses using traditional bulk sequencing methods. The application of single-cell... -
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- Influence of Polycomb Proteins and Epigenetic Transcriptional Modifiers on the Development and Activation of T Lymphocytes
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Chun T
- KMID: 2168218
- Hanyang Med Rev.
- 2013 Feb;33(1):33-38.
- doi: 10.7599/hmr.2013.33.1.33
Transcriptional regulation of a gene is not always correlated with genetic information inherited from parents because the transcription of specific genes is often governed by the modification of chromatin structure.... -
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- Epigenetic biomarkers: a step forward for understanding periodontitis
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Lindroth A, Park YJ
- KMID: 1798484
- J Periodontal Implant Sci.
- 2013 Jun;43(3):111-120.
- doi: 10.5051/jpis.2013.43.3.111
Periodontitis is a common oral disease that is characterized by infection and inflammation of the tooth supporting tissues. While its incidence is highly associated with outgrowth of the pathogenic microbiome,... -
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- Epigenetics: A key paradigm in reproductive health
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Bunkar N, Pathak N, Lohiya NK, Mishra PK
- KMID: 2308892
- Clin Exp Reprod Med.
- 2016 Jun;43(2):59-81.
- doi: 10.5653/cerm.2016.43.2.59
It is well established that there is a heritable element of susceptibility to chronic human ailments, yet there is compelling evidence that some components of such heritability are transmitted through... -
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- Classification of Colon Cancer Patients Based on the Methylation Patterns of Promoters
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Choi W, Lee J, Lee JY, Lee SM, Kim DW, Kim YJ
- KMID: 2328165
- Genomics Inform.
- 2016 Jun;14(2):46-52.
- doi: 10.5808/GI.2016.14.2.46
Diverse somatic mutations have been reported to serve as cancer drivers. Recently, it has also been reported that epigenetic regulation is closely related to cancer development. However, the effect of... -
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