- Adipose-Derived Stem Cell Transplantation Inhibits Vascular Inflammatory Responses and Endothelial Dysfunction in Rats with Atherosclerosis
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Fan M, Bai J, Ding T, Yang X, Si Q, Nie D
- KMID: 2460220
- Yonsei Med J.
- 2019 Nov;60(11):1036-1044.
- doi: 10.3349/ymj.2019.60.11.1036
PURPOSE: This study aimed to investigate the effect of adipose-derived stem cell (ADSC) transplantation on atherosclerosis (AS) and its underlying mechanisms. MATERIALS AND METHODS: In our study, rat AS model was... -
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- Neuroendocrine Dysregulation in Irritable Bowel Syndrome Patients: A Pilot Study
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Stasi C, Bellini M, Gambaccini D, Duranti E, de Bortoli N, Fani B, Albano E, Russo S, Sudano I, Laffi G, Taddei S, Marchi S, Bruno RM
- KMID: 2387834
- J Neurogastroenterol Motil.
- 2017 Jul;23(3):428-434.
- doi: 10.5056/jnm16155
BACKGROUND/AIMS: Irritable bowel syndrome (IBS) is a multifactorial disorder, involving dysregulation of brain-gut axis. Our aim was to evaluate the neuroendocrine activity in IBS. METHODS: Thirty IBS and 30 healthy volunteers... -
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- Sulfatase 1 mediates the inhibitory effect of angiotensin II type 2 receptor inhibitor on angiotensin II-induced hypertensive mediator expression and proliferation in vascular smooth muscle cells from spontaneously hypertensive rats
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Kim HY, Cha HJ, Kim HS
- KMID: 2400328
- Yeungnam Univ J Med.
- 2017 Jun;34(1):43-54.
- doi: 10.12701/yujm.2017.34.1.43
BACKGROUND: Extracellular sulfatases (Sulfs), sulfatase 1 (Sulf1) and sulfatase 2 (Sulf2), play a pivotal role in cell signaling by remodeling the 6-O-sulfation of heparan sulfate proteoglycans on the cell surface.... -
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- Impact of high serum Immunoglobulin E levels on the risk of atherosclerosis in humans
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Unal D, Gelincik A, Elitok A, Demir S, Olgac M, Coskun R, Kocaaga M, Colakoglu , Buyukozturk S
- KMID: 2396928
- Asia Pac Allergy.
- 2017 Apr;7(2):74-81.
- doi: 10.5415/apallergy.2017.7.2.74
BACKGROUND: Epidemiological studies show that immunoglobulin E (IgE) levels were higher in subjects with acute coronary events. However, it is unknown if the increased IgE level is a marker of... -
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- Therapeutic effect of prostaglandin E1 in monocrotaline-induced pulmonary arterial hypertension rats
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Lee JC
- KMID: 2390427
- Anat Cell Biol.
- 2017 Mar;50(1):60-68.
- doi: 10.5115/acb.2017.50.1.60
Pulmonary arterial hypertension (PAH) is a severe pulmonary vascular disease characterized by sustained increase in pulmonary arterial pressure and excessive thickening and remodeling of distal small pulmonary arteries. During disease... -
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- cAMP induction by ouabain promotes endothelin-1 secretion via MAPK/ERK signaling in beating rabbit atria
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Peng LQ, Li P, Zhang QL, Hong L, Liu LP, Cui X, Cui BR
- KMID: 2150468
- Korean J Physiol Pharmacol.
- 2016 Jan;20(1):9-14.
- doi: 10.4196/kjpp.2016.20.1.9
Adenosine 3',5'-cyclic monophosphate (cAMP) participates in the regulation of numerous cellular functions, including the Na(+)-K(+)-ATPase (sodium pump). Ouabain, used in the treatment of several heart diseases, is known to increase... -
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- The Effect of Umbilical Cord Blood Derived Mesenchymal Stem Cells in Monocrotaline-induced Pulmonary Artery Hypertension Rats
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Lee H, Lee JC, Kwon JH, Kim KC, Cho MS, Yang YS, Oh W, Choi SJ, Seo ES, Lee SJ, Wang TJ, Hong YM
- KMID: 2155470
- J Korean Med Sci.
- 2015 May;30(5):576-585.
- doi: 10.3346/jkms.2015.30.5.576
Pulmonary arterial hypertension (PAH) causes right ventricular failure due to a gradual increase in pulmonary vascular resistance. The purposes of this study were to confirm the engraftment of human umbilical... -
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- Effect of Enhanced External Counterpulsation and Cardiac Rehabilitation on Quality of Life, Plasma Nitric Oxide, Endothelin 1 and High Sensitive CRP in Patients With Coronary Artery Disease: A Pilot Study
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Shakouri S, Razavi Z, Eslamian F, Sadeghi-Bazargani H, Ghaffari S, Babaei-Ghazani A
- KMID: 2273040
- Ann Rehabil Med.
- 2015 Apr;39(2):191-198.
- doi: 10.5535/arm.2015.39.2.191
OBJECTIVE: To investigate the effect of enhanced external counterpulsation (EECP) on plasma nitric oxide (NO), Endothelin 1 (ET1), high sensitive C-reactive protein (HSCRP) and quality of life (QoL) in patients... -
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- Development of an Ex Vivo Model for the Study of Cerebrovascular Function Utilizing Isolated Mouse Olfactory Artery
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Lee HJ, Dietrich H, Han BH, Zipfel GJ
- KMID: 2067083
- J Korean Neurosurg Soc.
- 2015 Jan;57(1):1-5.
- doi: 10.3340/jkns.2015.57.1.1
OBJECTIVE: Cerebral vessels, such as intracerebral perforating arterioles isolated from rat brain, have been widely used as an ex vivo model to study the cerebrovascular function associated with cerebrovascular disorders... -
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- Role of Urinary Levels of Endothelin-1, Monocyte Chemotactic Peptide-1, and N-Acetyl Glucosaminidase in Predicting the Severity of Obstruction in Hydronephrotic Neonates
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Mohammadjafari H, Rafiei A, Mousavi SA, Alaee A, Yeganeh Y
- KMID: 2069791
- Korean J Urol.
- 2014 Oct;55(10):670-676.
- doi: 10.4111/kju.2014.55.10.670
PURPOSE: Antenatal hydronephrosis (AH) is found in 0.5%-1% of neonates. The aim of the study was to assess the urinary concentrations of 3 biomarkers, endothelin-1 (ET-1), monocyte chemotactic peptide-1 (MCP-1),... -
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- Histological and Biochemical Comparisons between Right Atrium and Left Atrium in Patients with Mitral Valvular Atrial Fibrillation
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Park JH, Lee JS, Ko YG, Lee SH, Lee BS, Kang SM, Chang BC, Pak HN
- KMID: 2223884
- Korean Circ J.
- 2014 Jul;44(4):233-242.
- doi: 10.4070/kcj.2014.44.4.233
BACKGROUND AND OBJECTIVES: It has been known that the dominant driver of atrial fibrillation (AF) exists in the left atrium (LA) and the incidence of systemic thromboembolism is higher than... -
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- Urine endothelin-1 as a Biomarker for Urinary Tract Infections in Children
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Kee HM, Yi DY, Yun KW, Lim IS
- KMID: 2196567
- J Korean Soc Pediatr Nephrol.
- 2014 Apr;18(1):36-41.
PURPOSE: Urinary tract infections (UTIs) are the most common source of bacterial infections in infants and young children. Accurate diagnosis and treatment is important because of their association with renal... -
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- Expression Changes of Endothelin-1, Endothelin Receptor A and B in the Cochlea after Noise Exposure
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Hur GM, Lyu AR, Han WK, Choi JW, Rha KS, Park YH
- KMID: 2277755
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2013 May;56(5):278-285.
- doi: 10.3342/kjorl-hns.2013.56.5.278
BACKGROUND AND OBJECTIVES: There are several evidences of reduced cochlea blood flow after noise exposure in the cochlea. However, the pathophysiology of blood flow change is still obscure, and endothelins,... -
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- An inhibitory effect of tumor necrosis factor-alpha antagonist to gene expression in monocrotaline-induced pulmonary hypertensive rats model
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Kwon JH, Kim KC, Cho MS, Kim HS, Sohn S, Hong YM
- KMID: 2284282
- Korean J Pediatr.
- 2013 Mar;56(3):116-124.
- doi: 10.3345/kjp.2013.56.3.116
PURPOSE: Tumor necrosis factor (TNF)-alpha is thought to contribute to pulmonary hypertension. We aimed to investigate the effect of infliximab (TNF-alpha antagonist) treatment on pathologic findings and gene expression in... -
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- Updates on the Treatment of Pulmonary Hypertension
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Lee SE, Chang HJ
- KMID: 1833842
- Korean J Med.
- 2013 Mar;84(3):346-356.
- doi: 10.3904/kjm.2013.84.3.346
Pulmonary arterial hypertension (PAH) is a rare and severe clinical condition characterized by luminal obliteration of small pulmonary arteries. It results in increased resistance to pulmonary blood flow, and ultimately,... -
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- Changes of Gene Expressions in Spontaneously Hypertensive Rat Model After Losartan Treatment
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Cha JH, Lee HR, Kim KC, Cho MS, Hong YM
- KMID: 2224976
- Korean Circ J.
- 2012 Nov;42(11):761-768.
- doi: 10.4070/kcj.2012.42.11.761
BACKGROUND AND OBJECTIVES: The renin angiotensin system seems to play an important role in the development of cardiac and vascular hypertrophy in hypertension. The changes in pathology, and gene expressions... -
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- Fluoxetine Protects against Big Endothelin-1 Induced Anti-Apoptosis by Rescuing Kv1.5 Channels in Human Pulmonary Arterial Smooth Muscle Cells
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Dai F, Mao Z, Xia J, Zhu S, Wu Z
- KMID: 1716887
- Yonsei Med J.
- 2012 Jul;53(4):842-848.
- doi: 10.3349/ymj.2012.53.4.842
PURPOSE: Pulmonary Kv channels are thought to play a crucial role in the regulation of cell proliferation and apoptosis. Previous studies have shown that fluoxetine upregulated the expression of Kv1.5... -
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- Is There Any Relationship between the Chronicity of Chronic Anal Fissure and Endothelin-1?
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Lim CH, Shin HK, Kang WH, Jeong SK, Yang HK
- KMID: 2198735
- J Korean Soc Coloproctol.
- 2011 Oct;27(5):237-240.
- doi: 10.3393/jksc.2011.27.5.237
PURPOSE: Many kinds of substances are produced on vascular endothelial activation. The aim of this study is to confirm an increase in Endothelin-1 (ET-1), the most potent vasoconstrictor, which is... -
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- Protective effect of 4,4'-diaminodiphenylsulfone against paraquat-induced mouse lung injury
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Cho SC, Rhim JH, Choi HR, Son YH, Lee SJ, Song KY, Park SC
- KMID: 1022129
- Exp Mol Med.
- 2011 Sep;43(9):525-537.
- doi: 10.3858/emm.2011.43.9.060
Although 4,4'-diaminodiphenylsulfone (DDS, dapsone) has been used to treat several dermatologic conditions, including Hansen disease, for the past several decades, its mode of action has remained a topic of debate.... -
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- Changes of Endothelin-1 in Rats Corpus Cavernosum Smooth Muscle of Partial Bladder Outlet Obstruction
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Kim KH, Seo YJ, Lee KS
- KMID: 2298623
- Korean J Androl.
- 2011 Apr;29(1):27-32.
- doi: 10.5534/kja.2011.29.1.27
PURPOSE: Lower urinary tract symptoms and erectile dysfunction (ED) are common disorders in men and increase with age. Recently, there has been evidence to suggest that patients with high benign... -
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