- Associations of + 138 Ins/del A and + 5665 G/T polymorphisms of endothelin-1 gene with hypertension in Burmese people in Magway, Myanmar
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Oo WM, Thiha K, Khine MM
- KMID: 2531227
- Clin Hypertens.
- 2022;28(1):20.
- doi: 10.1186/s40885-022-00201-w
Background: Hypertension is one of the major public health problems worldwide, and is one of the recognized causes of premature deaths every year in the world. The purpose of this... -
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- NOX4/Src regulates ANP secretion through activating ERK1/2 and Akt/GATA4 signaling in beating rat hypoxic atria
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Wu Cz, Li X, Hong L, Han Zn, Liu Y, Wei Cx, Cui X
- KMID: 2512959
- Korean J Physiol Pharmacol.
- 2021 Mar;25(2):159-166.
- doi: 10.4196/kjpp.2021.25.2.159
Nicotinamide adenine dinucleotide phosphate oxidases (NOXs) are the major enzymatic source of reactive oxygen species (ROS). NOX2 and NOX4 are expressed in the heart but its role in hypoxia-induced atrial... -
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- Neuroendocrine Dysregulation in Irritable Bowel Syndrome Patients: A Pilot Study
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Stasi C, Bellini M, Gambaccini D, Duranti E, de Bortoli N, Fani B, Albano E, Russo S, Sudano I, Laffi G, Taddei S, Marchi S, Bruno RM
- KMID: 2387834
- J Neurogastroenterol Motil.
- 2017 Jul;23(3):428-434.
- doi: 10.5056/jnm16155
BACKGROUND/AIMS: Irritable bowel syndrome (IBS) is a multifactorial disorder, involving dysregulation of brain-gut axis. Our aim was to evaluate the neuroendocrine activity in IBS. METHODS: Thirty IBS and 30 healthy volunteers... -
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- cAMP induction by ouabain promotes endothelin-1 secretion via MAPK/ERK signaling in beating rabbit atria
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Peng LQ, Li P, Zhang QL, Hong L, Liu LP, Cui X, Cui BR
- KMID: 2150468
- Korean J Physiol Pharmacol.
- 2016 Jan;20(1):9-14.
- doi: 10.4196/kjpp.2016.20.1.9
Adenosine 3',5'-cyclic monophosphate (cAMP) participates in the regulation of numerous cellular functions, including the Na(+)-K(+)-ATPase (sodium pump). Ouabain, used in the treatment of several heart diseases, is known to increase... -
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- Effect of Triflusal on Primary Vascular Dysregulation Compared with Aspirin: A Double-Blind, Randomized, Crossover Trial
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Shin S, Kim KJ, Cho IJ, Hong GR, Jang Y, Chung N, Rah YM, Chang HJ
- KMID: 2163613
- Yonsei Med J.
- 2015 Sep;56(5):1227-1234.
- doi: 10.3349/ymj.2015.56.5.1227
PURPOSE: Primary vascular dysregulation (PVD) is a condition in which the response to cold temperature or external stimuli is abnormal. We investigated whether triflusal use results in amelioration of PVD... -
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- Role of Urinary Levels of Endothelin-1, Monocyte Chemotactic Peptide-1, and N-Acetyl Glucosaminidase in Predicting the Severity of Obstruction in Hydronephrotic Neonates
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Mohammadjafari H, Rafiei A, Mousavi SA, Alaee A, Yeganeh Y
- KMID: 2069791
- Korean J Urol.
- 2014 Oct;55(10):670-676.
- doi: 10.4111/kju.2014.55.10.670
PURPOSE: Antenatal hydronephrosis (AH) is found in 0.5%-1% of neonates. The aim of the study was to assess the urinary concentrations of 3 biomarkers, endothelin-1 (ET-1), monocyte chemotactic peptide-1 (MCP-1),... -
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- Urine endothelin-1 as a Biomarker for Urinary Tract Infections in Children
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Kee HM, Yi DY, Yun KW, Lim IS
- KMID: 2196567
- J Korean Soc Pediatr Nephrol.
- 2014 Apr;18(1):36-41.
PURPOSE: Urinary tract infections (UTIs) are the most common source of bacterial infections in infants and young children. Accurate diagnosis and treatment is important because of their association with renal... -
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- Expression Changes of Endothelin-1, Endothelin Receptor A and B in the Cochlea after Noise Exposure
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Hur GM, Lyu AR, Han WK, Choi JW, Rha KS, Park YH
- KMID: 2277755
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2013 May;56(5):278-285.
- doi: 10.3342/kjorl-hns.2013.56.5.278
BACKGROUND AND OBJECTIVES: There are several evidences of reduced cochlea blood flow after noise exposure in the cochlea. However, the pathophysiology of blood flow change is still obscure, and endothelins,... -
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- Is There Any Relationship between the Chronicity of Chronic Anal Fissure and Endothelin-1?
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Lim CH, Shin HK, Kang WH, Jeong SK, Yang HK
- KMID: 2198735
- J Korean Soc Coloproctol.
- 2011 Oct;27(5):237-240.
- doi: 10.3393/jksc.2011.27.5.237
PURPOSE: Many kinds of substances are produced on vascular endothelial activation. The aim of this study is to confirm an increase in Endothelin-1 (ET-1), the most potent vasoconstrictor, which is... -
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- Changes of Endothelin-1 in Rats Corpus Cavernosum Smooth Muscle of Partial Bladder Outlet Obstruction
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Kim KH, Seo YJ, Lee KS
- KMID: 2298623
- Korean J Androl.
- 2011 Apr;29(1):27-32.
- doi: 10.5534/kja.2011.29.1.27
PURPOSE: Lower urinary tract symptoms and erectile dysfunction (ED) are common disorders in men and increase with age. Recently, there has been evidence to suggest that patients with high benign... -
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- The Role of Endothelin-1 in Obstructive Sleep Apnea Syndrome and Pulmonary Hypertension
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Choi Y
- KMID: 2317493
- Sleep Med Psychophysiol.
- 2010 Dec;17(2):69-74.
Obstructive sleep apnea syndrome is associated with significant cardiovascular morbidity and increased mortality. However, it was controversial whether obstructive sleep apnea syndrome could cause pulmonary hypertension. The controversy was resolved... -
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- Plasma C-Reactive Protein and Endothelin-1 Level in Patients with Chronic Obstructive Pulmonary Disease and Pulmonary Hypertension
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Kwon YS, Chi SY, Shin HJ, Kim EY, Yoon BK, Ban HJ, Oh IJ, Kim KS, Kim YC, Lim SC
- KMID: 2157854
- J Korean Med Sci.
- 2010 Oct;25(10):1487-1491.
- doi: 10.3346/jkms.2010.25.10.1487
Pulmonary hypertension is a frequent complication of chronic obstructive pulmonary disease (COPD) and associated with a worse survival and increased risk of hospitalization for exacerbation of COPD. However, little information... -
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- A Case of Sustained Severe Pulmonary Hypertension after Sugrical Repair of Atrial Septal Defect in a Patient with HIV Infection
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Kim WS, Park SH, Choi HJ, Han JJ
- KMID: 1457279
- J Korean Soc Hypertens.
- 2010 Sep;16(3):35-40.
We report a case of severe pulmonary hypertension in a patient with human immunodeficiency virus(HIV) infection. A 29-year-old woman with asymptomatic HIV infection was diagnosed as atrial septal defect(ASD) and... -
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- Effect of Stimulation Intensity and Location of Cerebral Infarction on Motor Evoked Potentials in the Rat
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Chae SH, Kwon HC, Hyun JK, Kim TU, Lee YI, Lee SJ
- KMID: 2326069
- J Korean Acad Rehabil Med.
- 2010 Aug;34(4):381-386.
OBJECTIVE: To investigate the change of motor evoked potential (MEP) in the cerebral infarction, and observe the effect of stimulation intensity and location of cerebral infarction, using rat model of... -
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- Ezrin and Endothelin-1 Expression in Dermatofibroma and Dermatofibrosarcoma Protuberans
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Youn SH, Choi WJ, Cho EB, Park HR, Park EJ, Kwon IH, Kim KH, Kim KJ
- KMID: 2301847
- Korean J Dermatol.
- 2010 Aug;48(8):678-683.
BACKGROUND: Distinction of dermatofibroma (DF) from dermatofibrosarcoma protuberans (DFSP) is occasionally difficult. Histologically, DF shows fibrohistiocyte growth, and DFSP shows myofibroblast proliferation. This difference is usually targeted by several immunohistochemical... -
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- Analysis of Systemic Factors through Blood Examination in Normal-Tension Glaucoma Patients
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Lee NY, Ahn MD
- KMID: 2213146
- J Korean Ophthalmol Soc.
- 2010 Feb;51(2):241-247.
- doi: 10.3341/jkos.2010.51.2.241
PURPOSE: In this study, we evaluated systemic hemodynamic factors of normal tension glaucoma. METHODS: Forty patients with normal tension glaucoma and thirty healthy people were investigated with regard to hemoglobin, hematocrit,... -
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- Expression of Endothelin-1 by Stimulation with CXCL8 in Mouse Peritoneal Macrophages
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Bae JJ, Kim JH, Kim H, Kim HS
- KMID: 1474163
- J Bacteriol Virol.
- 2009 Sep;39(3):205-216.
- doi: 10.4167/jbv.2009.39.3.205
Endothelin-1 (ET-1) has been characterized as a potent vasoconstrictor secreted by the endothelium, and play a major role in the regulation of vascular tone. It has been also known to... -
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- Changes in Evoked Potentials in Focal Cerebral Cortical Ischemia in the Rat
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Lee SJ, Park WB, Chae S, Lee YI, Kim TU
- KMID: 2325319
- J Korean Acad Rehabil Med.
- 2009 Apr;33(2):147-153.
OBJECTIVE: To investigate the changes of motor and somatosensory evoked potentials found in focal cerebral cortical ischemia induced by endothelin-1 (ET-1), one of the common models of cerebral infarct in... -
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- No association between endothelin-1 gene polymorphisms and preeclampsia in Korean population
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Kim SY, Park SY, Lim JH, Yang JH, Kim MY, Park HY, Lee KS, Ryu HM
- KMID: 2184445
- J Genet Med.
- 2008 Jun;5(1):34-40.
PURPOSE: Preeclampsia is a major cause of maternal and perinatal mortality and morbidity and is considered to be a multifactorial disorder involving a genetic predisposition and environmental factors. Endothelin-1 (ET-1)... -
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- Effects of Rosiglitazone on Heat Shock Protein and the Endothelin System in Deoxycorticosterone Acetate-Salt Hypertensive Rats
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Bae EH, Kim IJ, Park JW, Ma SK, Choi KC, Lee JU, Kim SW
- KMID: 2052299
- Electrolyte Blood Press.
- 2008 Jun;6(1):1-8.
- doi: 10.5049/EBP.2008.6.1.1
The deoxycorticosterone acetate (DOCA)-salt rat is known as a model of volume dependent hypertension and characterized by increased cardiac endothelin-1 (ET-1) content. Recently, it has been reported that rosiglitazone (RGT),... -
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