- Drug Repositioning: Exploring New Indications for Existing Drug-Disease Relationships
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Kim HS
- KMID: 2527137
- Endocrinol Metab.
- 2022 Feb;37(1):62-64.
- doi: 10.3803/EnM.2022.1403
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- Homeostatic Regulation of Glucose Metabolism by the Central Nervous System
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Choi JH, Kim MS
- KMID: 2527133
- Endocrinol Metab.
- 2022 Feb;37(1):9-25.
- doi: 10.3803/EnM.2021.1364
Evidence for involvement of the central nervous system (CNS) in the regulation of glucose metabolism dates back to the 19th century, although the majority of the research on glucose metabolism... -
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- The Influence of Obesity and Metabolic Health on Vascular Health
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Rhee EJ
- KMID: 2527132
- Endocrinol Metab.
- 2022 Feb;37(1):1-8.
- doi: 10.3803/EnM.2022.101
The prevalence of obesity is rapidly increasing worldwide. Obesity should not be understood only as the accumulation of fat in the body, but instead as a phenomenon that exerts different... -
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- Active Surveillance as an Effective Management Option for Low-Risk Papillary Thyroid Microcarcinoma
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Jeon MJ, Kim WG, Kim TY, Shong YK, Kim WB
- KMID: 2527149
- Endocrinol Metab.
- 2022 Feb;37(1):180-180.
- doi: 10.3803/EnM.2022.103
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- State-of-the-Art Overview of the Pharmacological Treatment of Non-Alcoholic Steatohepatitis
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Cho Y, Lee Yh
- KMID: 2527135
- Endocrinol Metab.
- 2022 Feb;37(1):38-52.
- doi: 10.3803/EnM.2022.102
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide, and non-alcoholic steatohepatitis (NASH), a subtype of NAFLD, can progress to cirrhosis, hepatocellular carcinoma, and... -
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- Development of Metabolic Synthetic Lethality and Its Implications for Thyroid Cancer
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Ju SH, Lee SE, Kang YE, Shong M
- KMID: 2527136
- Endocrinol Metab.
- 2022 Feb;37(1):53-61.
- doi: 10.3803/EnM.2022.1402
Cancer therapies targeting genetic alterations are a topic of great interest in the field of thyroid cancer, which frequently harbors mutations in the RAS, RAF, and RET genes. Unfortunately, U.S.... -
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- Recent Updates to Clinical Practice Guidelines for Diabetes Mellitus
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Yu J, Lee SH, Kim MK
- KMID: 2527134
- Endocrinol Metab.
- 2022 Feb;37(1):26-37.
- doi: 10.3803/EnM.2022.105
Guidelines for the management of patients with diabetes have become an important part of clinical practice that improve the quality of care and help establish evidence-based medicine in this field.... -
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- Dulaglutide Ameliorates Palmitic Acid-Induced Hepatic Steatosis by Activating FAM3A Signaling Pathway
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Lee J, Hong SW, Kim MJ, Moon SJ, Kwon H, Park SE, Rhee EJ, Lee WY
- KMID: 2527139
- Endocrinol Metab.
- 2022 Feb;37(1):74-83.
- doi: 10.3803/EnM.2021.1293
Background: Dulaglutide, a long-acting glucagon-like peptide-1 receptor agonist (GLP-1RA), has been shown to reduce body weight and liver fat content in patients with type 2 diabetes. Family with sequence similarity... -
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- Hip Fracture Risk According to Diabetic Kidney Disease Phenotype in a Korean Population
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Lee SE, Yoo J, Kim KA, Han K, Choi HS
- KMID: 2527145
- Endocrinol Metab.
- 2022 Feb;37(1):148-158.
- doi: 10.3803/EnM.2021.1315
Background: Diabetic kidney disease (DKD) is associated with an elevated risk of fractures. However, little is known about the association between proteinuric or non-proteinuric DKD and the risk of hip... -
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- Epidemiology and Long-Term Adverse Outcomes in Korean Patients with Congenital Adrenal Hyperplasia: A Nationwide Study
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Kim JH, Choi S, Lee YA, Lee J, Kim SG
- KMID: 2527144
- Endocrinol Metab.
- 2022 Feb;37(1):138-147.
- doi: 10.3803/EnM.2021.1328
Background: Previous studies on the epidemiology and complications of congenital adrenal hyperplasia (CAH) were conducted in Western countries and in children/adolescents. We aimed to explore the epidemiology of CAH, as... -
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- Risk and Risk Factors for Postpartum Type 2 Diabetes Mellitus in Women with Gestational Diabetes: A Korean Nationwide Cohort Study
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Choi MJ, Choi J, Chung CW
- KMID: 2527142
- Endocrinol Metab.
- 2022 Feb;37(1):112-123.
- doi: 10.3803/EnM.2021.1276
Background: There are differences in risk and risk factor findings of postpartum type 2 diabetes mellitus (T2DM) after gestational diabetes depending on study design and subjects of previous studies. This... -
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- Drug Repositioning Using Temporal Trajectories of Accompanying Comorbidities in Diabetes Mellitus
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Park N, Jeon JY, Jeong E, Kim S, Yoon D
- KMID: 2527138
- Endocrinol Metab.
- 2022 Feb;37(1):65-73.
- doi: 10.3803/EnM.2021.1275
Background: Most studies of systematic drug repositioning have used drug-oriented data such as chemical structures, gene expression patterns, and adverse effect profiles. As it is often difficult to prove repositioning... -
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- Human Leukocyte Antigens and Biomarkers in Type 1 Diabetes Mellitus Induced by Immune-Checkpoint Inhibitors
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Inaba H, Kaido Y, Ito S, Hirobata T, Inoue G, Sugita T, Yamamoto Y, Jinnin M, Kimura H, Kobayashi T, Iwama S, Arima H, Matsuoka T
- KMID: 2527140
- Endocrinol Metab.
- 2022 Feb;37(1):84-95.
- doi: 10.3803/EnM.2021.1282
Background: Type 1 diabetes mellitus induced by immune-checkpoint inhibitors (ICI-T1DM) is a rare critical entity. However, the etiology of ICI-T1DM remains unclear. Methods: In order to elucidate risk factors for ICI-T1DM,... -
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- Growth in Children with HLA-Conferred Susceptibility to Type 1 Diabetes
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Saare L, Peet A, Tillmann V
- KMID: 2527148
- Endocrinol Metab.
- 2022 Feb;37(1):175-179.
- doi: 10.3803/EnM.2021.1262
The incidence of type 1 diabetes (T1D) is increasing throughout the world. This trend may be explained by the accelerator hypothesis. Our study investigated growth, its biochemical markers, and their... -
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- Protocol for a Korean Multicenter Prospective Cohort Study of Active Surveillance or Surgery (KoMPASS) in Papillary Thyroid Microcarcinoma
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Jeon MJ, Kang YE, Moon JH, Lim DJ, Lee CY, Lee YS, Kim SW, Kim MH, Kim BH, Kang HC, Shong M, Cho SW, Kim WB
- KMID: 2527150
- Endocrinol Metab.
- 2022 Feb;37(1):181-182.
- doi: 10.3803/EnM.2022.104
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- Cardiovascular Outcomes with Finerenone According to Glycemic Status at Baseline and Prior Treatment with Newer Antidiabetics among Patients with Type 2 Diabetes Mellitus
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Patoulias D, Papadopoulos C, Karagiannis A, Vassilikos V, Doumas M
- KMID: 2527147
- Endocrinol Metab.
- 2022 Feb;37(1):170-174.
- doi: 10.3803/EnM.2021.1296
Type 2 diabetes mellitus (T2DM) and cardiovascular disease are closely interconnected. We sought to determine the cardioprotective action of finerenone according to prior treatment with newer antidiabetics and glycemic status.... -
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- Diagnostic Performance of Thyroid Core Needle Biopsy Using the Revised Reporting System: Comparison with Fine Needle Aspiration Cytology
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Kim K, Bae JS, Kim JS, Jung SL, Jung CK
- KMID: 2527146
- Endocrinol Metab.
- 2022 Feb;37(1):159-169.
- doi: 10.3803/EnM.2021.1299
Background: We aim to validate the diagnostic performance of thyroid core needle biopsy (CNB) for diagnosing malignancy in clinical settings to align with the changes made in recently updated thyroid... -
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- Adrenal Morphology as an Indicator of Long-Term Disease Control in Adults with Classic 21-Hydroxylase Deficiency
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Kim TM, Kim JH, Jang HN, Choi MH, Cho JY, Kim SY
- KMID: 2527143
- Endocrinol Metab.
- 2022 Feb;37(1):124-137.
- doi: 10.3803/EnM.2021.1278
Background: Monitoring adults with classical 21-hydroxylase deficiency (21OHD) is challenging due to variation in clinical and laboratory settings. Moreover, guidelines for adrenal imaging in 21OHD are not yet available. We... -
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- EW-7197 Attenuates the Progression of Diabetic Nephropathy in db/db Mice through Suppression of Fibrogenesis and Inflammation
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Ha KB, Sangartit W, Jeong AR, Lee ES, Kim HM, Shim S, Kukongviriyapan U, Kim DK, Lee EY, Chung CH
- KMID: 2527141
- Endocrinol Metab.
- 2022 Feb;37(1):96-111.
- doi: 10.3803/EnM.2021.1305
Background: Diabetic nephropathy (DN) is characterized by albuminuria and accumulation of extracellular matrix (ECM) in kidney. Transforming growth factor-β (TGF-β) plays a central role in promoting ECM accumulation. We aimed... -
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