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A Meaningful Journey to Predict Fractures with Deep Learning

Ha J

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Efficient Dissociation Protocol for Generation of Single Cell Suspension from Human Thyroid Tissue for Single Cell RNA Sequencing

Yi S, Kim HJ, Koo BS, Lee SE, Choi J, Kang YE

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Long-Term Outcomes of Congenital Adrenal Hyperplasia

Nordenström A, Lajic S, Falhammar H

A plethora of negative long-term outcomes have been associated with congenital adrenal hyperplasia (CAH). The causes are multiple and involve supra-physiological gluco- and mineralocorticoid replacement, excess adrenal androgens both intrauterine...
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Association between the Blautia/Bacteroides Ratio and Altered Body Mass Index after Bariatric Surgery

Kim Y, Son D, Kim BK, Kim KH, Seo KW, Jung K, Park SJ, Lim S, Kim JH

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Lipoprotein Lipase: Is It a Magic Target for the Treatment of Hypertriglyceridemia

Moon JH, Kim K, Choi SH

High levels of triglycerides (TG) and triglyceride-rich lipoproteins (TGRLs) confer a residual risk of cardiovascular disease after optimal low-density lipoprotein cholesterol (LDL-C)–lowering therapy. Consensus has been made that LDL-C is...
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Quality of Life of Survivors of Thyroid Cancer Is Not Inferior to That in Subjects without Cancer: Long-Term after Over 5 Years

Lee J, Lee YJ, Lim DJ, Lee JM, Chang SA, Kim MH

Background: Patients with thyroid cancer undergo less extensive surgery and additional therapies compared to those with other cancers. We aimed to compare the quality of life (QoL) between patients with...
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A Key Metabolic Regulator of Bone and Cartilage Health

Pérez-Hernández E, Pastrana-Carballo JJ, Gómez-Chávez F, Gupta RC, Pérez-Hernández N

Taurine, a cysteine-derived zwitterionic sulfonic acid, is a common ingredient in energy drinks and is naturally found in fish and other seafood. In humans, taurine is produced mainly in the...
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Characteristics of Glycemic Control and Long-Term Complications in Patients with Young-Onset Type 2 Diabetes

Baek Hs, Park JY, Yu J, Lee J, Yang Y, Ha J, Lee SH, Cho JH, Lim DJ, Kim HS

Background: The prevalence of young-onset diabetes (YOD) has been increasing worldwide. As the incidence of YOD increases, it is necessary to determine the characteristics of YOD and the factors that...
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Advances in Pituitary Surgery

Byun YH, Kang H, Kim YH

Pituitary surgery has advanced considerably in recent years with the exploration and development of various endoscopic approaches and techniques. Different endoscopic skull base approaches are being applied to access sellar...
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Clinical and Technical Aspects in Free Cortisol Measurement

Choi MH

Accurate measurement of cortisol is critical in adrenal insufficiency as it reduces the risk associated with misdiagnosis and supports the optimization of stress dose. Comprehensive assays have been developed to...
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Frequency of TERT Promoter Mutations in Real-World Analysis of 2,092 Thyroid Carcinoma Patients

Yang H, Park H, Ryu HJ, Heo J, Kim JS, Oh YL, Choe JH, Kim JH, Kim JS, Jang HW, Kim TH, Kim SW, Chung JH

Background: Telomerase reverse transcriptase (TERT) promoter mutations are associated with increased recurrence and mortality in patients with thyroid carcinoma. Previous studies on TERT promoter mutations were retrospectively conducted on a...
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The Effects of Irisin on the Interaction between Hepatic Stellate Cell and Macrophage in Liver Fibrosis

Do DV, Park SY, Nguyen GT, Choi DH, Cho EH

Background: Hepatic stellate cells (HSCs) are the central players interacting with multiple cell types in liver fibrosis. The crosstalk between HSCs and macrophages has recently become clearer. Irisin, an exercise-responsive...
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Protective Effect of Delta-Like 1 Homolog Against Muscular Atrophy in a Mouse Model

Lee JY, Lee M, Lee DH, Lee Yh, Lee BW, Kang ES, Cha BS

Background: Muscle atrophy is caused by an imbalance between muscle growth and wasting. Delta-like 1 homolog (DLK1), a protein that modulates adipogenesis and muscle development, is a crucial regulator of...
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High Cardiorespiratory Fitness Protects against Molecular Impairments of Metabolism, Heart, and Brain with Higher Efficacy in Obesity-Induced Premature Aging

Pantiya P, Thonusin C, Sumneang N, Ongnok B, Chunchai T, Kerdphoo S, Jaiwongkam T, Arunsak B, Siri-Angkul N, Sriwichaiin S, Chattipakorn N, Chattipakorn SC

Background: High cardiorespiratory fitness (CRF) protects against age-related diseases. However, the mechanisms mediating the protective effect of high intrinsic CRF against metabolic, cardiac, and brain impairments in non-obese versus obese...
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Development of a Spine X-Ray-Based Fracture Prediction Model Using a Deep Learning Algorithm

Kong SH, Lee JW, Bae BU, Sung JK, Jung KH, Kim JH, Shin CS

Background: Since image-based fracture prediction models using deep learning are lacking, we aimed to develop an X-ray-based fracture prediction model using deep learning with longitudinal data. Methods: This study included 1,595...
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