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In Memoriam: Remembering Professor Hun-Ki Min (1928–2021)

Cho YM

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New Era for Renal-Protective Therapy in Type 2 Diabetes: Better Renal Outcomes in Patients with Type 2 Diabetes Taking Sodium-Glucose Cotransporter 2 Inhibitors versus Dipeptidyl Peptidase-4 Inhibitors

Jung CH

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Identification of Maturity-Onset Diabetes of the Young Caused by Glucokinase Mutations Detected Using Whole-Exome Sequencing

Cho EH, Min JW, Choi SS, Choi HS, Kim SW

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Unilateral Thyroid-Associated Orbitopathy as the Only Sign of Occult Celiac Disease: Effective Treatment with a Gluten-Free Diet

Stramazzo I, Centanni M, Virili C

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Clinical Characteristics, Management, and Potential Biomarkers of Endocrine Dysfunction Induced by Immune Checkpoint Inhibitors

Iwama S, Kobayashi T, Arima H

Immune-related adverse events (irAEs) affecting the endocrine glands are among the most frequent irAEs induced by immune checkpoint inhibitors (ICIs) and include hypopituitarism, primary adrenal insufficiency, thyrotoxicosis, hypothyroidism, hypoparathyroidism, and...
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Diagnosis for Pheochromocytoma and Paraganglioma: A Joint Position Statement of the Korean Pheochromocytoma and Paraganglioma Task Force

Ku EJ, Kim KJ, Kim JH, Kim MK, Ahn CH, Lee KA, Lee SH, Lee YB, Park KH, Choi YM, Hong N, Hong AR, Kang SW, Park BK, Seong MW, Kim M, Jung KC, Jung CK, Cho YS, Paeng JC, Kim JH, Ryu OH, Rhee Y, Kim CH, Lee EJ

Pheochromocytoma and paraganglioma (PPGLs) are rare catecholamine-secreting neuroendocrine tumors but can be life-threatening. Although most PPGLs are benign, approximately 10% have metastatic potential. Approximately 40% cases are reported as harboring...
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An Update on Contraception in Polycystic Ovary Syndrome

Oguz SH, Yildiz BO

Polycystic ovary syndrome (PCOS) is a common endocrine disorder in reproductive-aged women, characterized by hyperandrogenism, oligo/anovulation, and polycystic ovarian morphology. Combined oral contraceptives (COCs), along with lifestyle modifications, represent the...
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Cumulative Exposure to Metabolic Syndrome Components and the Risk of Dementia: A Nationwide Population-Based Study

Cho Y, Han K, Kim DH, Park YM, Yoon KH, Kim MK, Lee SH

Background: Metabolic disturbances are modifiable risk factors for dementia. Because the status of metabolic syndrome (MetS) and its components changes over time, we aimed to investigate the association of the...
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Gender-Dependent Reference Range of Serum Calcitonin Levels in Healthy Korean Adults

Song E, Jeon MJ, Yoo HJ, Bae SJ, Kim TY, Kim WB, Shong YK, Kim HK, Kim WG

Background: Serum calcitonin measurement contains various clinical and methodological aspects. Its reference level is wide and unclear despite sensitive calcitonin kits are available. This study aimed to identify the specific...
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Efficacy and Safety of the Novel Dipeptidyl Peptidase-4 Inhibitor Gemigliptin in the Management of Type 2 Diabetes: A Meta-Analysis

Dutta D, Agarwal A, Maisnam I, Singla R, Khandelwal D, Sharma M

Background: No meta-analysis has holistically analysed and summarised the efficacy and safety of gemigliptin in type 2 diabetes. The meta-analysis addresses this knowledge gap. Methods: Electronic databases were searched for randomised...
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Effect of CCL11 on In Vitro Myogenesis and Its Clinical Relevance for Sarcopenia in Older Adults

Kim DA, Park SJ, Lee JY, Kim JH, Lee S, Lee E, Jang IY, Jung HW, Park JH, Kim BJ

Background: The C-C motif chemokine ligand 11 (CCL11) has been receiving attention as a potential pro-aging factor. Accordingly, it may be involved in muscle metabolism and sarcopenia, a key component...
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Continuous Glucose Monitoring in the Hospital

Perez-Guzman MC, Shang T, Zhang JY, Jornsay D, Klonoff DC

Continuous glucose monitors (CGMs) have suddenly become part of routine care in many hospitals. The coronavirus disease 2019 (COVID-19) pandemic has necessitated the use of new technologies and new processes...
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Digital Therapeutics for Obesity and Eating-Related Problems

Kim M, Choi HJ

In recent years, digital technologies have rapidly advanced and are being applied to remedy medical problems. These technologies allow us to monitor and manage our physical and mental health in...
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Dopaminergic Control of the Feeding Circuit

Baik JH

There is increasing evidence demonstrating that reward-related motivational food intake is closely connected with the brain’s homeostatic system of energy balance and that this interaction might be important in the...
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Diagnostic Accuracy of Computed Tomography in Predicting Primary Aldosteronism Subtype According to Age

Lee SH, Kim JW, Yoon HK, Koh JM, Shin CS, Kim SW, Kim JH

Background: Guidelines by the Endocrine Society Guideline on bypassing adrenal vein sampling (AVS) in patients
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Food Preferences and Obesity

Spinelli S, Monteleone E

Obesity is a multifactorial disease with several potential causes that remain incompletely understood. Recent changes in the environment, which has become increasingly obesogenic, have been found to interact with individual...
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Operationalizing Treat-to-Target for Osteoporosis

Lewiecki EM

Treat-to-target (TTT) for osteoporosis is a concept for individualizing patient treatment decisions that focuses on achieving an acceptable level of fracture risk rather than response to treatment alone. While a...
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Role of PCSK9 Inhibitors in Patients with Familial Hypercholesterolemia

Tomlinson B, Patil NG, Fok M, Lam CWK

Patients with familial hypercholesterolemia (FH) are at high or very high risk for cardiovascular disease. Those with heterozygous FH (HeFH) often do not reach low-density lipoprotein cholesterol (LDL-C) targets with...
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Associations of GNAS Mutations with Surgical Outcomes in Patients with Growth Hormone-Secreting Pituitary Adenoma

Jung H, Kim K, Kim D, Moon JH, Kim EH, Kim SH, Ku CR, Lee EJ

Background: The guanine nucleotide-binding protein, alpha stimulating (GNAS) gene has been associated with growth hormone (GH)-secreting pituitary adenoma. We investigated the prevalence of GNAS mutations in Korean patients with acromegaly...
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Cardiorenal Protection in Diabetic Kidney Disease

Lee JF, Berzan E, Sridhar VS, Odutayo A, Cherney DZ

Over the last 5 years there have been many new developments in the management of diabetic kidney disease. Glucagon-like peptide-1 receptor agonists (GLP-1 RA) and sodium-glucose cotransporter-2 (SGLT2) inhibitors were...
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