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Brief Review of Articles in 'Endocrinology and Metabolism' in 2013

Lee WY

No abstract available.
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Cost-of-Illness Trend of Thyroid Gland Disease in Korea

Chung JH

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Response: The Biochemical Prognostic Factors of Subclinical Hypothyroidism (Endocrinol Metab 2014;29:154-62, Myung Won Lee et al.)

Lee MW, Lee EJ

No abstract available.
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Letter: The Biochemical Prognostic Factors of Subclinical Hypothyroidism (Endocrinol Metab 2014;29:154-62, Myung Won Lee et al.)

Ahn HY, Chung YJ

No abstract available.
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Effects of Increased Iodine Intake on Thyroid Disorders

Sun X, Shan Z, Teng W

Iodine is a micronutrient essential for the production of thyroid hormones. Iodine deficiency is the most common cause of preventable mental impairment worldwide. Universal salt iodization (USI) has been introduced...
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Molecular Pathogenesis and Targeted Therapies in Well-Differentiated Thyroid Carcinoma

Kim JG

Four proto-oncogenes commonly associated with well-differentiated thyroid carcinoma, rearranged during transfection (RET)/papillary thyroid cancer, BRAF, RAS, and PAX8/peroxisome proliferator activated receptor-gamma, may carry diagnostic and prognostic significance. These oncogenes can...
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Adult Multisystem Langerhans Cell Histiocytosis Presenting with Central Diabetes Insipidus Successfully Treated with Chemotherapy

Choi JE, Lee HR, Ohn JH, Moon MK, Park J, Lee SJ, Choi MG, Yoo HJ, Kim JH, Hong EG

We report the rare case of an adult who was diagnosed with recurrent multisystem Langerhans cell histiocytosis (LCH) involving the pituitary stalk and lung who present with central diabetes insipidus...
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Testosterone Deficiency Associated with Poor Glycemic Control in Korean Male Diabetics

Kim JS, Kim BS, Jeon JY, Choi YJ, Chung YS

BACKGROUND: Recent studies have shown that men with diabetes have lower testosterone levels than healthy men. However, studies on the correlation between testosterone and diabetes are rare in Korea. We...
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Accelerated Disease Progression after Discontinuation of Sorafenib in a Patient with Metastatic Papillary Thyroid Cancer

Yun KJ, Kim W, Kim EH, Kim MH, Lim DJ, Kang MI, Cha BY

Distant metastases from papillary thyroid carcinoma (PTC) are rare and are associated with a poor prognosis. Here, we describe a patient with metastatic PTC who was treated with a tyrosine...
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A Novel Long-Acting Glucagon-Like Peptide-1 Agonist with Improved Efficacy in Insulin Secretion and beta-Cell Growth

Kim HY, Hwang JI, Moon MJ, Seong JY

BACKGROUND: Glucagon-like peptide-1 (GLP-1) is an incretin hormone produced by cleavage of proglucagon in intestinal L-cells. In the pancreas, GLP-1 stimulates post-prandial insulin secretion, promotes insulin biosynthesis, and improves insulin...
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Insufficient Experience in Thyroid Fine-Needle Aspiration Leads to Misdiagnosis of Thyroid Cancer

Son JI, Rhee SY, Woo JT, Park WS, Byun JK, Kim YJ, Byun JM, Chin SO, Chon S, Oh S, Kim SW, Kim YS

BACKGROUND: Fine-needle aspiration (FNA) of the thyroid is a widely accepted confirmatory test for thyroid cancer with high sensitivity and specificity. FNA is a simple procedure that is learned by...
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Radioiodine Therapy in Differentiated Thyroid Cancer: The First Targeted Therapy in Oncology

Chung JK, Cheon GJ

Iodide uptake across the membranes of thyroid follicular cells and cancer cells occurs through an active transport process mediated by the sodium-iodide symporter (NIS). The rat and human NIS-coding genes...
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Can Robotic Thyroidectomy Be Performed Safely in Thyroid Carcinoma Patients?

Chai YJ, Lee KE, Youn YK

Since the adoption of the Da Vinci robotic system for remote access thyroid surgery, robotic thyroidectomy (RT) has become a popular surgical option for patients who want to avoid neck...
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Effect of Resveratrol, a SIRT1 Activator, on the Interactions of the CLOCK/BMAL1 Complex

Park I, Lee Y, Kim HD, Kim K

BACKGROUND: In mammals, the CLOCK/BMAL1 heterodimer is a key transcription factor complex that drives the cyclic expression of clock-controlled genes involved in various physiological functions and behavioral consequences. Recently, a...
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Early Prediction of Long-Term Response to Cabergoline in Patients with Macroprolactinomas

Lee Y, Ku CR, Kim EH, Hong JW, Lee EJ, Kim SH

BACKGROUND: Cabergoline is typically effective for treating prolactinomas; however, some patients display cabergoline resistance, and the early characteristics of these patients remain unclear. We analyzed early indicators predicting long-term response...
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Age Is the Strongest Effector for the Relationship between Estimated Glomerular Filtration Rate and Coronary Artery Calcification in Apparently Healthy Korean Adults

Chae HB, Lee SY, Kim NH, Han KJ, Lee TH, Jang CM, Yoo KM, Park HJ, Lee MK, Jeon WS, Park SE, Moon HS, Park CY, Lee WY, Oh KW, Park SW, Rhee EJ

BACKGROUND: Chronic kidney disease (CKD) is considered one of the most common risk factors for cardiovascular disease. Coronary artery calcification (CAC) is a potential mechanism that explains the association between...
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Protective Effects of Inducible HO-1 on Oxygen Toxicity in Rat Brain Endothelial Microvessel Cells

Yoo SJ, Nakra NK, Ronnett GV, Moon C

BACKGROUND: Reperfusion in ischemia is believed to generate cytotoxic oxidative stress, which mediates reperfusion injury. These stress conditions can initiate lipid peroxidation and damage to proteins, as well as promote...
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Cost-of-Illness Trends Associated with Thyroid Disease in Korea

Hyun KR, Kang S, Lee S

BACKGROUND: The purpose of this study is to analyze the scale of and trends associated with the cost-of-illness of thyroid disease in Korea at 2-year intervals during the last 10...
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Current Status and Future Perspectives in Differentiated Thyroid Cancer

Kim TY, Kim WG, Kim WB, Shong YK

Thyroid cancer is increasing all over the world. The exact cause of this increase is still debated and there are conflicting reports. Sophisticated molecular studies suggest that environmental chemicals may...
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Polarized and Stage-Dependent Distribution of Immunoreactivity for Novel PDZ-Binding Protein Preso1 in Adult Neurogenic Regions

Lee ES, Kim WR, Kim Y, Lee HW, Kim H, Sun W

BACKGROUND: Adult neural stem cells have the potential for self-renewal and differentiation into multiple cell lineages via symmetric or asymmetric cell division. Preso1 is a recently identified protein involved in...
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