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SARS-CoV-2 Delta Variant Breakthrough Infection and Onward Secondary Transmission in Household

Yi S, Kim JM, Choe YJ, Hong S, Choi S, Ahn SB, Kim M, Park YJ

Background: Despite the extraordinary speed of mass vaccination efforts, an outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delta variant in a vaccinee with coronavirus disease 2019 (COVID-19) mRNA...
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A cost-effectiveness study of universal screening for hepatitis C virus infection in South Korea: A societal perspective

Kim HL, Kim KA, Choi GH, Jang ES, Ki M, Choi HY, Jeong SH

Background/Aims: This study aimed to evaluate the cost-effectiveness of hepatitis C virus (HCV) screening compared to no screening in the Korean population from societal and healthcare system perspectives. Methods: A published...
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The Concept of Economic Evaluation and Its Application in Thyroid Cancer Research

Kim K, Kim M, Lim W, Kim BH, Park SK

Economic evaluation is a type of comparative analysis between interventions in terms of both their resource use and health outcomes. Due to the good prognosis of thyroid cancer (TC), the...
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Cost-Effectiveness Analysis of Immunotherapy in Patient with Allergic Rhinitis

Park JY, Kim YS, Kim JK, Cho JH

Background and Objectives All treatments must be effective and affordable. Although it is clear that immunotherapy is effective in patients with allergic rhinitis, no cost-effectiveness analysis has been conducted in...
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Cost-Effectiveness Analysis of Positive Airway Pressure in Patient with Obstructive Sleep Apnea

Kim H, Kim JK, Cho JH

Background and Objectives: Positive airway pressure (PAP) is effective at reducing the number of complications in patients with obstructive sleep apnea (OSA). To the best of our knowledge, no cost-effectiveness...
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Safety and Effectiveness of Cytomegalovirus Specific Antigen Induced Interferon-Gamma ELISPOT/ELISA: A Systematic Review

Choi W, Hahn J, Lee W, Shin C

Background: This study evaluated the safety and effectiveness of the cytomegalovirus (CMV) Specific Antigen Induced Interferon-Gamma ELISPOT (enzyme-linked immunosorbent spot)/ELISA (enzyme-linked immunosorbent assay) procedure in predicting the risk of CMV...
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Real-world Effectiveness and Safety of Direct-acting Antiviral Agents in Patients with Chronic Hepatitis C Genotype 2 Infection: Korean Multicenter Study

Kang YW, Baek YH, Lee SW, Park SJ, Yoon JS, Yoon KT, Hong Y, Heo NY, Seo KI, Lee SS, Cho HC, Shin JW

Background: The advancement of treatment with direct-acting antiviral (DAA) agents has improved the cure rate of hepatitis C virus (HCV) infection close to 100%. The aim of our study was...
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Policy Suggestions to Improve Patient Access to New Drugs in Korea

Choi Y, Lee H

Objective: This study aimed to overview and assess the effectiveness of the policies and regulations that have governed new drug access in Korea, and to propose policies to enhance patient...
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Influenza Vaccine Effectiveness in Children at the Emergency Department during the 2018-2019 Season: the First Season School-aged Children Were Included in the Korean Influenza National Immunization Program

Yoon Y, Choi Js, Park M, Cho H, Park M, Huh HJ, Kim YJ, Son MH

Background: For the 2018–2019 season, the national influenza immunization program expanded to cover children aged from 6 months to 12 years in Korea. This study aimed to analyze vaccine effectiveness...
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Surgical revascularization for Moyamoya disease in the United States: A cost-effectiveness analysis

Wali AR, Santiago-Dieppa DR, Srinivas S, Brandel MG, Steinberg JA, Rennert RC, Mandeville R, Murphy JD, Olson S, Pannell JS, Khalessi AA

Objective: Moyamoya disease (MMD) is a vasculopathy of the internal carotid arteries with ischemic and hemorrhagic sequelae. Surgical revascularization confers upfront peri-procedural risk and costs in exchange for long-term protective...
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Cariprazine Add-on in Inadequate Clozapine Response: A Report on Two Cases

Berardis DD, Rapini G, Olivieri L, Giardini A, Lauretis ID, Serroni N, Orsolini L, Fornaro M, Iasevoli F, Trotta S, Cottura P, Vellante F, Alessandrini M, Giannantonio MD

Cariprazine is a novel antipsychotic drug that exerts partial agonism of dopamine D2 /D3 receptors with preferential binding to the D 3 receptor, antagonism of 5HT2B receptors, and partial agonism...
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Rapid Symptom Improvement in Major Depressive Disorder Using Accelerated Repetitive Transcranial Magnetic Stimulation

Kim SJ, Son SJ, Jang M, Kim BH, Hong SJ, Seo L, Choi SW, Seok JH, Noh JS

Objective: Repetitive transcranial magnetic stimulation (rTMS) has contributed to increase in the remission rate for patients with major depressive disorder (MDD). However, current rTMS treatment is practically inconvenient because it...
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Current Status and Future Directions of Hepatocellular Carcinoma Surveillance Test Based on Cost-effective Analysis

An J

Detection of hepatocellular carcinoma (HCC) at an early stage enables patients to receive curative treatment with survival gains. Current international liver society guidelines recommend the enrollment of patients at high...
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The Role of Needle-Based Confocal Laser Endomicroscopy in the Evaluation of Pancreatic Cystic Lesions: A Systematic Review

Chin YK, Wu CCH, Tan DMY

The prevalence of pancreatic cystic lesions (PCLs) has increased recently due to the increased use of cross-sectional abdominal imaging and the ageing global population. Current diagnostic techniques are inadequate to...
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Effectiveness of Stimulant Medications on Disruptive Behavior and Mood Problems in Young Children

Parsley I, Zhang Z, Hausmann M, Lerdahl A, Vaughan B, Edwards R, Hwang S

Objective: There are very few studies on the effectiveness of stimulant medications for the treatment of disruptive mood and behavior problems in young children (less than 7 years) with Disruptive...
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Efficacy and Cost-effectiveness of Surgical Biopsy for Histologic Diagnosis of Indeterminate Nodules Suspected for Early Stage Lung Cancer: Comparison with Percutaneous Needle Biopsy

Na KJ, Park IK, Park S, Kang CH, Kim YT

Background: Indeterminate pulmonary nodules (IPN) suspected for early stage lung cancer mandate accurate diagnosis. Both percutaneous needle biopsy (PCNB) and surgical biopsy (SB) are valuable options. The present study aimed...
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Structural Relationship between Nurses' Occupational Motivation and Effectiveness based on the Job Crafting Model

Hyun MS

Purpose: This study was to investigate the structural relationship between nurses' motivation and effectiveness in their occupations using the Job Crafting model. This study was identified that the nurses' occupational...
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Systematic evidence of health economic evaluation of drugs for postmenopausal osteoporosis: A quality appraisal

Azharuddin M, Adil M, Khan RA, Ghosh P, Kapur P, Sharma M

This paper systematically and critically reviewed all published economic evaluations of drugs for the treatment postmenopausal osteoporosis. A systematic search was conducted using relevant databases for economic evaluations to include...
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Treatment of Children and Adolescents with Epilepsy with Atomoxetine

Park KJ, Ahn H, Yum MS, Ko TS, Kim HW

Objective The objective of this study was to assess the effectiveness and safety of atomoxetine in Korean children and adolescents with epilepsy. Methods We retrospectively reviewed the electronic medical records of...
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Review of the Existing Relative Biological Effectiveness Models for Carbon Ion Beam Therapy

Kim Y, Kim J, Cho S

Hadron therapy, such as carbon and helium ions, is increasingly coming to the fore for the treatment of cancers. Such hadron therapy has several advantages over conventional radiotherapy using photons...
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