- Modulation of calcium current by cyclic GMP in the single ventricular myocytes of the rabbit
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Ahnn JH, Suh KP, Earm YE
- KMID: 1686432
- Korean J Thorac Cardiovasc Surg.
- 1992 Apr;25(4):364-382.
No abstract available. -
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- Erratum: Korean J Physiol Pharmacol 2006 Feb;10(1):19-24. Differential Functional Expression of Clotrimazole-sensitive Ca2+ -activated K+ Current in Bal-17 and WEHI-231 Murine B Lymphocytes
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Zheng H, Ko JH, Nam JH, Earm YE, Kim SJ
- KMID: 2071628
- Korean J Physiol Pharmacol.
- 2006 Apr;10(2):109-109.
No abstract available. -
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- A preliminary observation on watery content of small intestine in Metagonimus yokogawai infected dog
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Cho SY, Kim SI, Earm YE, Ho WK
- KMID: 1715174
- Korean J Parasitol.
- 1985 Jun;23(1):175-177.
- doi: 10.3347/kjp.1985.23.1.175
The intestinal contents of a dog infected with 49,732 M. yokogawai for 8 weeks were normal but in a 4-week-old infection the intestinal water content correlated roughly with the number... -
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- The effects of intracellular monocarboxylates on the ATP-sensitive potassium channels in rabbit ventricular myocytes
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Kim N, Han J, Kim YE, Ho WK, Earm YE
- KMID: 2071538
- Korean J Physiol Pharmacol.
- 1998 Oct;2(5):581-589.
A regulating mechanism of the ATP-sensitive potassium channels (KATP channels) is yet to fully explained. This study was carried out to investigate the effects of intracellular application of monocarboxylates (acetate, formate, lactate, and... -
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- Effect of propofol, an intravenous anesthetic agent, on KATP channels of pancreatic beta-cells in rats
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Park EJ, Song DK, Cheun JK, Bae JI, Ho WK, Earm YE
- KMID: 1580632
- Korean J Physiol Pharmacol.
- 2000 Feb;4(1):25-31.
ATP-sensitive potassium channels (KATP channels) play an important role in insulin secretion from pancreatic beta cells. We have investigated the effect of propofol on KATP channels in cultured single pancreatic beta cells of... -
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- A Survey of Students' Satisfaction on Medical Education
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Kim CY, Kim SM, Seo JD, Earm YE, Ahn YO, Kim S, Chai JY, Lee SH
- KMID: 2306983
- Korean J Med Educ.
- 1996 Dec;8(2):169-188.
Objectives: To evaluate undergraduate medical education in Korea, we aimed at the development of the students' satisfaction questionnaire. Also analysis of the factors affecting student satisfa ction was intended. Subjects:... -
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- Effects of cyclic-GMP on hyperpolarization-activated inward current (I|f) in sino-atrial node cells of rabbit
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Shin Y, Ho WK, Earm YE
- KMID: 2285191
- Korean J Physiol Pharmacol.
- 1997 Dec;1(6):731-739.
The aim of present study is to investigate the effects of cGMP on hyperpolarization activated inward current (If), pacemaker current of the heart, in rabbit sino-atrial node cells using the whole-cell patch clamp... -
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- Differential Functional Expression of Clotrimazole-sensitive Ca2+-activated K+ Current in Bal-17 and WEHI-231 Murine B Lymphocytes
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Zheng H, Ko JH, Nam JH, Earm YE, Kim SJ
- KMID: 1512937
- Korean J Physiol Pharmacol.
- 2006 Feb;10(1):19-24.
The intermediate conductance Ca2+-activated K+ channels (SK4, IKCa1) are present in lymphocytes, and their membrane expression is upregulated by various immunological stimuli. In this study, the activity of SK4 was... -
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- The role of K+ channels on spontaneous action potential in rat clonal pituitary GH3 cell line
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Rhim H, Baek HJ, Ho WK, Earm YE
- KMID: 1982593
- Korean J Physiol Pharmacol.
- 2000 Apr;4(2):81-90.
The types of K+ channel which determine the pattern of spontaneous action potential (SAP) were investigated using whole-cell variation of patch clamp techniques under current- and voltage-clamp recording conditions in rat clonal pituitary... -
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- Role of Stretch-Activated Channels in Stretch-Induced Changes of Electrical Activity in Rat Atrial Myocytes
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Youm JB, Jo SH, Leem CH, Ho WK, Earm YE
- KMID: 1517035
- Korean J Physiol Pharmacol.
- 2004 Feb;8(1):33-41.
We developed a cardiac cell model to explain the phenomenon of mechano-electric feedback (MEF), based on the experimental data with rat atrial myocytes. It incorporated the activity of ion channels,... -
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- Are Medical Educators Satisfied with Educational Environment and Their Practice in Medical Schools?
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Kim CY, Kim S, Seo JD, Earm YE, Ahn YO, Kim S, Chai JY, Lee SH
- KMID: 2306973
- Korean J Med Educ.
- 1997 May;9(1):37-53.
OBJECTIVES: To evaluate undergraduate medical education in Korea, we investigated educators' satisfaction. Also analysis of the factors affecting educator satisfaction was intended. SUBJECTS: Of the entire educators(4,683 persons) of all medical... -
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- Effects of Na-Ca Exchange Mechanism on the Action Potential and Membrane Currents in the Single Cells of the Guinea-Pig and the Rabbit Heart
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Kim JH, Lim HK, Lee BH, Lee CK, Earm YE
- KMID: 1670375
- Korean Circ J.
- 1989 Mar;19(1):63-76.
- doi: 10.4070/kcj.1989.19.1.63
In single atrial and ventricular cells isolated from the guinea-pig and the rabbit heart, action potentials and membrane currents were recorded by using the whole cell voltage clamp technique. In... -
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- Effect of metabolic inhibition on inward rectifier K current in single rabbit ventricular myocytes
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Chung YJ, Ho WK, Earm YE
- KMID: 2285192
- Korean J Physiol Pharmacol.
- 1997 Dec;1(6):741-748.
In the present study, we have investigated the effect of metabolic inhibition on the inward rectifer K current (IK1). Using whole cell patch clamp technique we applied voltage ramp from +80 mV... -
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- 4-Aminopyridine Inhibits the Large-conductance Ca2+ -activated K+ Channel (BKCa) Currents in Rabbit Pulmonary Arterial Smooth Muscle Cells
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Bae YM, Kim A, Kim B, Cho SI, Kim J, Earm YE
- KMID: 1607350
- Korean J Physiol Pharmacol.
- 2003 Feb;7(1):25-28.
Ion channel inhibitors are widely used for pharmacological discrimination between the different channel types as well as for determination of their functional role. In the present study, we tested the... -
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- Modulation of L-type Ca2+ channel currents by various protein kinase activators and inhibitors in rat clonal pituitary GH3 cell line
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Bae YM, Baek HJ, Cho HN, Earm YE, Ho WK
- KMID: 2285234
- Korean J Physiol Pharmacol.
- 2001 Apr;5(2):139-146.
L-type Ca2+ channels play an important role in regulating cytosolic Ca2+ and thereby regulating hormone secretions in neuroendocrine cells. Since hormone secretions are also regulated by various kinds of protein kinases, we investigated... -
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- Reduced dihydroxyacetone sensitivity and normal sensitivity to glyceraldehyde and oxidizing agent of ATP-sensitive K+ channels of pancreatic beta cells in NIDDM rats
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Song DK, Park WK, Bae JH, Park MK, Kim SJ, Ho WK, Earm YE
- KMID: 1081048
- J Korean Med Sci.
- 1997 Aug;12(4):286-292.
- doi: 10.3346/jkms.1997.12.4.286
The inhibition of ATP-sensitive K+(KATP) channels in pancreatic beta cells is a key step of insulin secretion induced by glucose. Glucose-induced insulin secretion from the beta cells is selectively... -
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- Acidic pH-activated Cl- Current and Intracellular Ca2+ Response in Human Keratinocytes
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Park SJ, Choi WW, Kwon OS, Chung JH, Eun HC, Earm YE, Kim SJ
- KMID: 1838356
- Korean J Physiol Pharmacol.
- 2008 Aug;12(4):177-183.
- doi: 10.4196/kjpp.2008.12.4.177
The layers of keratinocytes form an acid mantle on the surface of the skin. Herein, we investigated the effects of acidic pH on the membrane current and [Ca2+](c) of human... -
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- Modeling of Arrhythmogenic Automaticity Induced by Stretch in Rat Atrial Myocytes
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Youm JB, Leem CH, Zhang YH, Kim N, Han J, Earm YE
- KMID: 1486109
- Korean J Physiol Pharmacol.
- 2008 Oct;12(5):267-274.
- doi: 10.4196/kjpp.2008.12.5.267
Since first discovered in chick skeletal muscles, stretch-activated channels (SACs) have been proposed as a probable mechano-transducer of the mechanical stimulus at the cellular level. Channel properties have been studied... -
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- Higher Expression of TRPM7 Channels in Murine Mature B Lymphocytes than Immature Cells
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Kim JK, Ko JH, Nam JH, Woo JE, Min KM, Earm YE, Kim SJ
- KMID: 2285312
- Korean J Physiol Pharmacol.
- 2005 Apr;9(2):69-75.
TRPM7, a cation channel protein permeable to various metal ions such as Mg2+, is ubiquitously expressed in variety of cells including lymphocytes. The activity of TRPM7 is tightly regulated by... -
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- Increase of L-type calcium current by cGMP-dependent protein kinase regulates in rabbit ventricular myocytes
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Han J, Kim N, Kim E, Ho W, Earm YE, Kim H
- KMID: 2071832
- Korean J Physiol Pharmacol.
- 1998 Dec;2(6):733-742.
BACKGROUND: We have previously reported that not only cGMP but also 8-Br-cGMP or 8-pCPT-cGMP, specific and potent stimulators of cGMP-dependent protein kinase (cGMP-PK), increased basal L-type calcium current (ICa) in rabbit ventricular myocytes.... -
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