- Dynorphin and enkephalin mRNAs in the rat forebrain by in situ hynridization histochmistry
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Lee MH, Suh YS
- KMID: 1686711
- Korean J Anat.
- 1992 Jun;25(2):179-187.
No abstract available. -
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- Effects of an Opiate Receptor Antagonist Naloxone on Endotoxic Shock and Tumorigenesis
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Ha TY, Ko YS, Moon SR
- KMID: 1547846
- Korean J Immunol.
- 1997 Mar;19(1):91-106.
Septic shock is one of the leading cause of death in hospitalized patients and mortality rates of up to 50 % have been reported. Despite all efforts, no regimen today... -
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- Opioid-induced hyperalgesia
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Lee H
- KMID: 2194833
- J Korean Med Assoc.
- 2014 Jan;57(1):41-46.
- doi: 10.5124/jkma.2014.57.1.41
Perioperative opioid-induced hyperalgesia (OIH) can be defined as the "increased perception of pain after opioid-based anesthesia and surgery" since hyperalgesia is defined as "increased pain from a stimulus that normally... -
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- Comprehensive Review on Kisspeptin and Its Role in Reproductive Disorders
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Clarke H, Dhillo WS, Jayasena C
- KMID: 2282002
- Endocrinol Metab.
- 2015 Jun;30(2):124-141.
- doi: 10.3803/EnM.2015.30.2.124
Kisspeptin has recently emerged as a key regulator of the mammalian reproductive axis. It is known that kisspeptin, acting centrally via the kisspeptin receptor, stimulates secretion of gonadotrophin releasing hormone... -
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- The effects of nalbuphine and fentanyl on experimental spinal cord injuries
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Lee WH
- KMID: 1752552
- Korean J Anesthesiol.
- 1994 May;27(5):428-448.
- doi: 10.4097/kjae.1994.27.5.428
Opiate receptor agonists (especially dynorphin - a kappa receptor agonist) have found to increase in the injuried segment of spinal cord. It is known to cause spinal cord damage when... -
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- The effects of kainate-induced Seizure on the Opioid Peptide Gene Expression in Rat Hippocampus
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Park KW, Park MK, Kim BJ, Ko SB, Kang YH, Lee DH
- KMID: 1957293
- J Korean Neurol Assoc.
- 1994 Dec;12(4):614-622.
In the rat hippocampal formation, the time-course and dose-response of the expression of enkephalin and dynorphin gene were examined after kainate (KA) treatment with in situ hybridization histochemistry. The KA... -
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- Changes of Neuropeptides in the Basal Ganglia of Hemiparkinsonian Rat Model
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Park KW, Lee DH, Park MK, Kim BJ, Ko SB, Suh YS
- KMID: 1957292
- J Korean Neurol Assoc.
- 1994 Dec;12(4):604-613.
We used in situ hybridization histochemistry with synthetic oligonucleotide probes to examined the effects of unilateral 6-hydroxydopamine lesions (which eliminated tyrosine hydroxylase mRNA containing cells in mesencephalon) on enkephalin, dynorphin,... -
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- Distribution of Neuropeptide mRNA-Containing Neurons and Changes of Their Gene Expression in the Rat Periaqueductal Gray in a Neuropathic Pain Model
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Huh SM, Kim JG, Bae MA, Kim DS, Park MJ, Jo HJ
- KMID: 1529457
- Korean J Anat.
- 1997 Jun;30(3):205-214.
The distribution of enkephalin, dynorphin, substance P and neurotensin in the periaqueductal gray[PAG] has been well established by immunohistochemical methods. However, there is little information about the regional distribution of... -
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- Regulation of DREAM Expression by Group I mGluR
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Lee J, Kim I, Oh SR, Ko SJ, Lim MK, Kim DG, Kim CH
- KMID: 2285413
- Korean J Physiol Pharmacol.
- 2011 Apr;15(2):95-100.
- doi: 10.4196/kjpp.2011.15.2.95
DREAM (downstream regulatory element antagonistic modulator) is a calcium-binding protein that regulates dynorphin expression, promotes potassium channel surface expression, and enhances presenilin processing in an expression level-dependent manner. However, no... -
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- Dual effect of dynorphin A on single-unit spike potentials in rat trigeminal nucleus
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Lee KM, Han HS, Jang JH, Ahn DK, Park JS
- KMID: 1606936
- Korean J Physiol Pharmacol.
- 2001 Jun;5(3):213-221.
The amygdala is known as a site for inducing analgesia, but its action on the trigeminal nucleus has not been known well. Little information is available on the effect of dynorphin on... -
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- The Gene Expression of Dynorphin, Enkephalin, c-Fos in the Neuropathic Rat
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Han NH, Lee WH, Hwang WJ, Yoon SH, Shin YS, Son SC, Kim HJ, Choi SJ, Lim K, Hwang BD
- KMID: 2239060
- Korean J Anesthesiol.
- 1996 Sep;31(3):293-303.
- doi: 10.4097/kjae.1996.31.3.293
BACKGROUND: We studied the time course of gene expression of dynorphin, enkephalin, c-fos, and the changes of allodynia, and the effect of chemical sympathectomy on the gene expression and allodynia... -
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- The Effect of Unilateral Dopaminergic Deafferentation on Kainic acid Induced Seizures in the Rat
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Park KW, Lee DH
- KMID: 2066049
- J Korean Neurol Assoc.
- 1996 Mar;14(1):114-125.
There has been quite a number of research regarding the role of dopamine in epilepsy and it has been still very controversial, In this study, the effect of dopaminergic deafferentation... -
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- Relationship of Longitudinal Extent of Hippocampal Sclerosis to Clinical Characteristics, Hippocampal Neuronal Cell Loss and Dynorphin-Immunoreactivity Patterns in Intractable Temporal Lobe Epilepsy with Hippocampal Sclerosis
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Kim JS, Kim JS, Kim SY, Seo JS
- KMID: 1539058
- J Korean Epilepsy Soc.
- 1999 Jun;3(1):16-21.
PURPOSE: In mesial temporal lobe epilepsy (TLE). Hippocampl sclerosis (HS) is a pathologic substrate and characterized by significant neuronal loss and band-like synaptic reorganization in dentate inner molecular layer (DGIML)... -
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- Dynorphin A (1-17) was Selective tomicro-Opioid Receptor in Agonist-Stimulated [35S] GTPgammaS Binding in Cortical and Thalamic Membranes of Monkey
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Lee H, Lee SA, Kang SY, Kim DY, Kim CH
- KMID: 2032239
- Korean J Anesthesiol.
- 2005 Apr;48(4):412-416.
- doi: 10.4097/kjae.2005.48.4.412
BACKGROUND: Dynorphin A (1-17) is conceived as an endogenous opioid peptide with a high degree of selectivity forkappa- opioid receptor even though it has been reported to sometimes act like... -
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- Opioids and the Gastrointestinal Tract: A Case of Narcotic Bowel Syndrome and Literature Review
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Farmer AD, Ferdinand , Aziz Q
- KMID: 2325978
- J Neurogastroenterol Motil.
- 2013 Jan;19(1):94-98.
The worldwide use of opiates is increasing yet there is little evidence that in long-term, non-cancer patients, they have an efficacious effect on functional outcomes and quality of life measures.... -
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- Changes of Smoking Urge and Endogenous Opioids, Prolactin, ACTH, Cortisol Levels in Nicotine Dependents with Naltrexone Pretreatment
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Sohn IK, Lee YS, Na C
- KMID: 1636033
- J Korean Neuropsychiatr Assoc.
- 2003 Jul;42(4):476-484.
OBJECTIVES: There is a controversy on the mechanism of nicotine dependence. Some suggest that the negative reinforcement such as withdrawal symptoms plays an important role, but others suggest that the... -
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