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Suppression of the ERK–SRF axis facilitates somatic cell reprogramming

Huh S, Song HR, Jeong GR, Jang H, Seo NH, Lee JH, Yi JY, Lee B, Choi HW, Do JT, Kim JS, Lee SH, Jung JW, Lee T, Shim J, Han MK, Lee TH

The molecular mechanism underlying the initiation of somatic cell reprogramming into induced pluripotent stem cells (iPSCs) has not been well described. Thus, we generated single-cell-derived clones by using a combination...
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Neuronal Differentiation of a Human Induced Pluripotent Stem Cell Line (FS-1) Derived from Newborn Foreskin Fibroblasts

Kwon J, Lee N, Jeon I, Lee HJ, Do JT, Lee DR, Oh SH, Shin DA, Kim A, Song J

  • KMID: 1735408
  • Int J Stem Cells.
  • 2012 Nov;5(2):140-145.
Isolation of induced pluripotent stem cells (iPSCs) from fully differentiated somatic cells has revolutionized existing concepts of cell differentiation and stem cells. Importantly, iPSCs generated from somatic cells of patients...
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Fertilization and in vitro Development of Bovine Oocytes Following Round Spermatid Injection

Um JH, Do JT, Kim NH, Park HD, Lee HT, Chung KS

  • KMID: 2235730
  • Korean J Fertil Steril.
  • 1999 Aug;26(2):193-201.
SUMMARY: In this study we determined fertilization processes and developmental ability of porcine oocytes following injection of round spermatid in the presence of artificial activation. Electrical stimulation at 3 h...
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Activation of Porcine Oocytes Following Intracytoplasmic Injection of Various Sperm Components and foreign species spermatozoa

Jun SH, Shin JS, Do JT, Kwon JK, Kim NH, Lee HT, Chung KS

  • KMID: 1930531
  • Korean J Fertil Steril.
  • 1998 Dec;25(3):331-340.
SUMMARY: We determined the incidence of activation, male pronuclear formation and apposition of pronuclei in porcine oocytes following intracytoplasmic injection of various porcine sperm components and foreign species spermatozoa, such...
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Microtubule and Chromatic Organization in Bovine Oocytes following Intracytoplasmic Injection of Spermatozoon, Sperm Head and Tail

Do JT, Jun SH, Choi JT, Kang YS, Lee BY, Kim SB, Kim NH, Lee HT, Chung KS

  • KMID: 2235762
  • Korean J Fertil Steril.
  • 1997 Dec;24(3):301-309.
SUMMARY: The objective of this study was to determine the microtubule assembly and chromatin configuration during the first cell cycle in bovine oocytes following injection of spermatozoon, sperm head and...
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